| mRNA vaccines for infectious diseases: principles, delivery and clinical translation N Chaudhary, D Weissman, KA Whitehead Nature reviews Drug discovery 20 (11), 817-838, 2021 | 1093 | 2021 |
| The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs ST LoPresti, ML Arral, N Chaudhary, KA Whitehead Journal of Controlled Release 345, 819-831, 2022 | 170 | 2022 |
| A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo KA Hajj, JR Melamed, N Chaudhary, NG Lamson, RL Ball, SS Yerneni, ... Nano letters 20 (7), 5167-5175, 2020 | 121 | 2020 |
| Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer JR Melamed, SS Yerneni, ML Arral, ST LoPresti, N Chaudhary, ... Science Advances 9 (4), eade1444, 2023 | 103 | 2023 |
| Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery JR Melamed, KA Hajj, N Chaudhary, D Strelkova, ML Arral, N Pardi, ... Journal of Controlled Release 341, 206-214, 2022 | 72 | 2022 |
| The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology JP Gleeson, KC Fein, N Chaudhary, R Doerfler, AN Newby, ... International journal of pharmaceutics 593, 120120, 2021 | 33 | 2021 |
| Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations JP Gleeson, N Chaudhary, KC Fein, R Doerfler, P Hredzak-Showalter, ... Science Advances 8 (26), eabm6865, 2022 | 31 | 2022 |
| Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes N Chaudhary, AN Newby, ML Arral, SS Yerneni, ST LoPresti, R Doerfler, ... Proceedings of the National Academy of Sciences 121 (11), e2307810121, 2024 | 27* | 2024 |
| The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism DMS Petersen, N Chaudhary, ML Arral, RM Weiss, KA Whitehead European Journal of Pharmaceutics and Biopharmaceutics 192, 126-135, 2023 | 27 | 2023 |
| The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery NG Lamson, KC Fein, JP Gleeson, AN Newby, S Xian, K Cochran, ... Proceedings of the National Academy of Sciences 119 (33), e2207829119, 2022 | 22* | 2022 |
| Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d N Chaudhary, LN Kasiewicz, AN Newby, ML Arral, SS Yerneni, ... Nature Biomedical Engineering 8 (11), 1483-1498, 2024 | 8 | 2024 |
| Non‐Viral RNA Delivery During Pregnancy: Opportunities and Challenges N Chaudhary, AN Newby, KA Whitehead Small 20 (41), 2306134, 2024 | 3 | 2024 |
| Factor XII silencing using siRNA prevents thrombus formation in a rat model of extracorporeal life support N Umei, S Shin, A Lai, J Miller, K Roberts, D Strelkova, N Chaudhary, ... ASAIO Journal 69 (6), 527-532, 2023 | 3 | 2023 |
| Branched‐Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice DMS Petersen, RM Weiss, KA Hajj, SS Yerneni, N Chaudhary, AN Newby, ... Advanced Healthcare Materials 13 (22), 2400225, 2024 | 2 | 2024 |
| Characterization and comparison of human and mouse milk cells R Doerfler, S Yerneni, A Newby, N Chaudhary, A Shu, K Fein, ... Plos one 19 (1), e0297821, 2024 | 2 | 2024 |
| Maternal milk cell components are uptaken by infant liver macrophages via extracellular vesicle mediated transport R Doerfler, S Yerneni, S LoPresti, N Chaudhary, A Newby, JR Melamed, ... The FASEB Journal 39 (2), e70340, 2025 | | 2025 |
| Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines EL Meany, JH Klich, CK Jons, T Mao, N Chaudhary, A Utz, J Baillet, ... bioRxiv, 2024.07. 05.602305, 2024 | | 2024 |
Kathryn A. WhiteheadProfessor of Chemical Engineering, Carnegie Mellon UniversityVerified email at cmu.edu