Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor DMW Zaiss, J Van Loosdregt, A Gorlani, CPJ Bekker, A Gröne, M Sibilia, ... Immunity 38 (2), 275-284, 2013 | 426 | 2013 |
Efficient identification of novel Hla-A* 0201–Presented Cytotoxic T Lymphocyte epitopes in the widely expressed tumor antigen prame by Proteasome-Mediated digestion analysis JH Kessler, NJ Beekman, SA Bres-Vloemans, P Verdijk, PA van Veelen, ... The Journal of experimental medicine 193 (1), 73-88, 2001 | 376 | 2001 |
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity J van Loosdregt, V Fleskens, J Fu, AB Brenkman, CPJ Bekker, ... Immunity 39 (2), 259-271, 2013 | 346 | 2013 |
The role of the proteasome in the generation of MHC class I ligands and immune responses E Sijts, PM Kloetzel Cellular and Molecular Life Sciences 68, 1491-1502, 2011 | 343 | 2011 |
Canonical Wnt signaling negatively modulates regulatory T cell function J Van Loosdregt, V Fleskens, MM Tiemessen, M Mokry, R van Boxtel, ... Immunity 39 (2), 298-310, 2013 | 240 | 2013 |
A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation F Ossendorp, M Eggers, A Neisig, T Ruppert, M Groettrup, A Sijts, ... Immunity 5 (2), 115-124, 1996 | 226 | 1996 |
Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes AJAM Sijts, T Ruppert, B Rehermann, M Schmidt, U Koszinowski, ... The Journal of experimental medicine 191 (3), 503-514, 2000 | 207 | 2000 |
Major differences in transporter associated with antigen presentation (TAP)-dependent translocation of MHC class I-presentable peptides and the effect of flanking sequences. A Neisig, J Roelse, AJ Sijts, F Ossendorp, MC Feltkamp, WM Kast, ... Journal of immunology (Baltimore, Md.: 1950) 154 (3), 1273-1279, 1995 | 199 | 1995 |
Hepatitis C virus mutation affects proteasomal epitope processing U Seifert, H Liermann, V Racanelli, A Halenius, M Wiese, H Wedemeyer, ... The Journal of clinical investigation 114 (2), 250-259, 2004 | 196 | 2004 |
MHC class I antigen processing of an adenovirus CTL epitope is linked to the levels of immunoproteasomes in infected cells AJAM Sijts, S Standera, REM Toes, T Ruppert, NJCM Beekman, ... The Journal of Immunology 164 (9), 4500-4506, 2000 | 171 | 2000 |
Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28 T van Hall, A Sijts, M Camps, R Offringa, C Melief, PM Kloetzel, ... The Journal of experimental medicine 192 (4), 483-494, 2000 | 167 | 2000 |
The role of the proteasome activator PA28 in MHC class I antigen processing A Sijts, Y Sun, K Janek, S Kral, A Paschen, D Schadendorf, PM Kloetzel Molecular immunology 39 (3-4), 165-169, 2002 | 163 | 2002 |
Expression of the proteasome activator PA28 rescues the presentation of a cytotoxic T lymphocyte epitope on melanoma cells Y Sun, AJAM Sijts, M Song, K Janek, AK Nussbaum, S Kral, M Schirle, ... Cancer research 62 (10), 2875-2882, 2002 | 142 | 2002 |
Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells. MS Villanueva, AJ Sijts, EG Pamer Journal of immunology (Baltimore, Md.: 1950) 155 (11), 5227-5233, 1995 | 141 | 1995 |
The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes DMW Zaiss, S Standera, H Holzhütter, PM Kloetzel, AJAM Sijts FEBS letters 457 (3), 333-338, 1999 | 138 | 1999 |
PI31 is a modulator of proteasome formation and antigen processing DMW Zaiss, S Standera, PM Kloetzel, AJAM Sijts Proceedings of the National Academy of Sciences 99 (22), 14344-14349, 2002 | 136 | 2002 |
MHC class I antigen processing of Listeria monocytogenes proteins: implications for dominant and subdominant CTL responses EG Pamer, AJAM Sijts, MS Villanueva, DH Busch, S Vijh Immunological reviews 158 (1), 129-136, 1997 | 135 | 1997 |
Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies. AJ Sijts, A Neisig, J Neefjes, EG Pamer Journal of immunology (Baltimore, Md.: 1950) 156 (2), 685-692, 1996 | 132 | 1996 |
Abrogation of CTL epitope processing by single amino acid substitution flanking the C-terminal proteasome cleavage site NJ Beekman, PA van Veelen, T van Hall, A Neisig, A Sijts, M Camps, ... The Journal of Immunology 164 (4), 1898-1905, 2000 | 118 | 2000 |
Enhanced intracellular dissociation of major histocompatibility complex class I–associated peptides: a mechanism for optimizing the spectrum of cell surface–presented cytotoxic … AJAM Sijts, EG Pamer The Journal of experimental medicine 185 (8), 1403-1412, 1997 | 110 | 1997 |