| Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ... Nature genetics 49 (3), 416-425, 2017 | 312 | 2017 |
| Genetic risk factors for the development of allergic disease identified by genome‐wide association MA Portelli, E Hodge, I Sayers Clinical & Experimental Allergy 45 (1), 21-31, 2015 | 266 | 2015 |
| Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study N Shrine, MA Portelli, C John, MS Artigas, N Bennett, R Hall, J Lewis, ... The Lancet Respiratory Medicine 7 (1), 20-34, 2019 | 234 | 2019 |
| Genetic basis for personalized medicine in asthma M Portelli, I Sayers Expert review of respiratory medicine 6 (2), 223-236, 2012 | 86 | 2012 |
| Phenotypic and functional translation of IL33 genetics in asthma ME Ketelaar, MA Portelli, FN Dijk, N Shrine, A Faiz, CJ Vermeulen, CJ Xu, ... Journal of Allergy and Clinical Immunology 147 (1), 144-157, 2021 | 48 | 2021 |
| Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels MA Portelli, M Siedlinski, CE Stewart, DS Postma, MA Nieuwenhuis, ... The FASEB Journal 28 (2), 923, 2014 | 40 | 2014 |
| Whole Exome Re-Sequencing Implicates CCDC38 and Cilia Structure and Function in Resistance to Smoking Related Airflow Obstruction LV Wain, I Sayers, M Soler Artigas, MA Portelli, E Zeggini, M Obeidat, ... PLoS genetics 10 (5), e1004314, 2014 | 39 | 2014 |
| Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium MA Portelli, FN Dijk, ME Ketelaar, N Shrine, J Hankinson, S Bhaker, ... JCI insight 5 (8), 2020 | 37 | 2020 |
| Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients MA Portelli, C Moseley, CE Stewart, DS Postma, P Howarth, JA Warner, ... Allergy 72 (3), 473-482, 2017 | 20 | 2017 |
| Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma D Ierodiakonou, MA Portelli, DS Postma, GH Koppelman, J Gerritsen, ... European Respiratory Journal 47 (5), 1568-1571, 2016 | 12 | 2016 |
| Cigarette smoke and the induction of urokinase plasminogen activator receptor in vivo: selective contribution of isoforms to bronchial epithelial phenotype MA Portelli, CE Stewart, IP Hall, CE Brightling, I Sayers American journal of respiratory cell and molecular biology 53 (2), 174-183, 2015 | 9 | 2015 |
| Understanding Society Scientific G LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ... | 8 | 2017 |
| Mepolizumab-induced Changes in Nasal Methylome and Transcriptome to Predict Response in Asthma K Rakkar, YL Pang, P Rajasekar, MA Portelli, RJ Hall, RL Clifford, D Shaw, ... American Journal of Respiratory and Critical Care Medicine 209 (10), 1268-1272, 2024 | 6 | 2024 |
| Human bronchial epithelial cells from patients with asthma have an altered gene expression profile S Bhaker, MA Portelli, K Rakkar, D Shaw, S Johnson, C Brightling, ... ERJ Open Research 8 (1), 2022 | 4 | 2022 |
| Translational analysis of moderate to severe asthma GWAS signals into candidate causal genes and their functional, tissue-dependent and disease-related associations MA Portelli, K Rakkar, S Hu, Y Guo, IM Adcock, I Sayers Frontiers in Allergy 2, 738741, 2021 | 4 | 2021 |
| Genome-wide association studies in asthma MA Portelli, I Sayers eLS, 2017 | 4 | 2017 |
| Gene expression and DNA methylation changes induced by Mepolizumab in the nasal epithelium in severe asthma K Rakkar, YL Pang, P Rajasekar, MA Portelli, R Hall, RL Clifford, D Shaw, ... European Respiratory Journal 60 (suppl 66), 2022 | 3 | 2022 |
| Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity J O'Loughlin, RJ Hall, S Bhaker, MA Portelli, A Henry, V Pang, DO Bates, ... ERJ Open Research 7 (1), 2021 | 3 | 2021 |
| Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity MA Portelli, S Bhaker, V Pang, DO Bates, SR Johnson, AP Mazar, D Shaw, ... Clinical and Translational Allergy 13 (10), e12293, 2023 | 2 | 2023 |
| A genome wide association study of moderate-severe asthma in subjects from the United Kingdom N Shrine, M Soler-Artigas, M Portelli, N Bennett, I Ntalla, A Henry, ... European Respiratory Journal 50 (suppl 61), 2017 | 2 | 2017 |
Professor Ian SayersUniversity of NottinghamVerified email at nottingham.ac.uk