Novel mechanisms of apoptosis induced by histone deacetylase inhibitors MJ Peart, KM Tainton, AA Ruefli, AE Dear, KA Sedelies, LA O’Reilly, ... Cancer research 63 (15), 4460-4471, 2003 | 328 | 2003 |
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma RK Lindemann, A Newbold, KF Whitecross, LA Cluse, AJ Frew, L Ellis, ... Proceedings of the National Academy of Sciences 104 (19), 8071-8076, 2007 | 250 | 2007 |
A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules H Liu, AE Dear, LB Knudsen, RW Simpson Journal of Endocrinology 201 (1), 59, 2009 | 241 | 2009 |
A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model T Gaspari, HB Liu, I Welungoda, Y Hu, RE Widdop, LB Knudsen, ... Diabetes and Vascular Disease Research 8 (2), 117-124, 2011 | 238 | 2011 |
Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte–matrix interactions J Golledge, M Karan, CS Moran, J Muller, P Clancy, AE Dear, PE Norman European heart journal 29 (5), 665-672, 2008 | 232 | 2008 |
Association of statin prescription with small abdominal aortic aneurysm progression CD Ferguson, P Clancy, B Bourke, PJ Walker, A Dear, T Buckenham, ... American heart journal 159 (2), 307-313, 2010 | 231 | 2010 |
The GLP-1 receptor agonist liraglutide inhibits progression of vascular disease via effects on atherogenesis, plaque stability and endothelial function in an ApoE−/− mouse model T Gaspari, I Welungoda, RE Widdop, RW Simpson, AE Dear Diabetes and Vascular Disease Research 10 (4), 353-360, 2013 | 176 | 2013 |
Association between osteopontin and human abdominal aortic aneurysm J Golledge, J Muller, N Shephard, P Clancy, L Smallwood, C Moran, ... Arteriosclerosis, thrombosis, and vascular biology 27 (3), 655-660, 2007 | 170 | 2007 |
Dapagliflozin attenuates human vascular endothelial cell activation and induces vasorelaxation: A potential mechanism for inhibition of atherogenesis T Gaspari, I Spizzo, HB Liu, Y Hu, RW Simpson, RE Widdop, AE Dear Diabetes and Vascular Disease Research 15 (1), 64-73, 2018 | 129 | 2018 |
Association between metformin prescription and growth rates of abdominal aortic aneurysms J Golledge, J Moxon, J Pinchbeck, G Anderson, S Rowbotham, J Jenkins, ... Journal of British Surgery 104 (11), 1486-1493, 2017 | 129 | 2017 |
The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation SM Krishna, A Dear, JM Craig, PE Norman, J Golledge Atherosclerosis 228 (2), 295-305, 2013 | 113 | 2013 |
Dual epigenetic targeting with panobinostat and azacitidine in acute myeloid leukemia and high-risk myelodysplastic syndrome P Tan, A Wei, S Mithraprabhu, N Cummings, HB Liu, M Perugini, K Reed, ... Blood cancer journal 4 (1), e170-e170, 2014 | 104 | 2014 |
The urokinase‐type‐plasminogen‐activator receptor (CD87) is a pleiotropic molecule AE Dear, RL Medcalf European journal of biochemistry 252 (2), 185-193, 1998 | 102 | 1998 |
Glucagon-like peptide-1 attenuates tumour necrosis factor-alpha-mediated induction of plasminogen [corrected] activator inhibitor-1 expression. H Liu, Y Hu, RW Simpson, AE Dear The Journal of endocrinology 196 (1), 57-65, 2008 | 99 | 2008 |
Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells F Wightman, HK Lu, AE Solomon, S Saleh, AN Harman, AL Cunningham, ... Aids 27 (18), 2853-2862, 2013 | 87 | 2013 |
Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin A Newbold, RK Lindemann, LA Cluse, KF Whitecross, AE Dear, ... Molecular cancer therapeutics 7 (5), 1066-1079, 2008 | 83 | 2008 |
Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm SM Krishna, AE Dear, PE Norman, J Golledge Atherosclerosis 212 (1), 16-29, 2010 | 79 | 2010 |
Thiazolidinediones inhibit TNFα induction of PAI-1 independent of PPARγ activation HB Liu, YS Hu, RL Medcalf, RW Simpson, AE Dear Biochemical and Biophysical Research Communications 334 (1), 30-37, 2005 | 77 | 2005 |
Epigenetic modulators and the new immunotherapies AE Dear New England Journal of Medicine 374 (7), 684-686, 2016 | 69 | 2016 |
A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice A Vinh, TA Gaspari, HB Liu, LF Dousha, RE Widdop, AE Dear Journal of vascular research 45 (2), 143-152, 2008 | 63 | 2008 |