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Kyle Upton
Kyle Upton
NHMRC Research Fellow, School of Chemisty and Molecular Biosciences - University of Queensland
Verified email at mater.uq.edu.au
Title
Cited by
Cited by
Year
Somatic retrotransposition alters the genetic landscape of the human brain
JK Baillie, MW Barnett, KR Upton, DJ Gerhardt, TA Richmond, F De Sapio, ...
Nature 479 (7374), 534-537, 2011
8382011
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma
R Shukla, KR Upton, M Muñoz-Lopez, DJ Gerhardt, ME Fisher, T Nguyen, ...
Cell 153 (1), 101-111, 2013
4392013
Ubiquitous L1 mosaicism in hippocampal neurons
KR Upton, DJ Gerhardt, JS Jesuadian, SR Richardson, ...
Cell 161 (2), 228-239, 2015
3762015
Extensive somatic L1 retrotransposition in colorectal tumors
S Solyom, AD Ewing, EP Rahrmann, T Doucet, HH Nelson, MB Burns, ...
Genome research 22 (12), 2328-2338, 2012
3102012
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
S Klawitter, NV Fuchs, KR Upton, M Munoz-Lopez, R Shukla, J Wang, ...
Nature communications 7 (1), 10286, 2016
1512016
Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus
C Pridans, A Raper, GM Davis, J Alves, KA Sauter, L Lefevre, T Regan, ...
The Journal of Immunology 201 (9), 2683-2699, 2018
1252018
The efficient generation of induced pluripotent stem (iPS) cells from adult mouse adipose tissue-derived and neural stem cells
PA Tat, H Sumer, KL Jones, K Upton, PJ Verma
Cell transplantation 19 (5), 525-536, 2010
1052010
L1 retrotransposon heterogeneity in ovarian tumor cell evolution
THM Nguyen, PE Carreira, FJ Sanchez-Luque, SN Schauer, AC Fagg, ...
Cell reports 23 (13), 3730-3740, 2018
602018
Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme
PE Carreira, AD Ewing, G Li, SN Schauer, KR Upton, AC Fagg, S Morell, ...
Mobile DNA 7, 1-14, 2016
402016
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines
JC Jiang, KR Upton
Mobile DNA 10, 1-14, 2019
332019
High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier
KD Hulme, L Yan, RJ Marshall, CJ Bloxham, KR Upton, SZ Hasnain, ...
Elife 9, e56907, 2020
312020
Reprogramming of somatic cells after fusion with induced pluripotent stem cells and nuclear transfer embryonic stem cells
H Sumer, KL Jones, J Liu, C Heffernan, PA Tat, KR Upton, PJ Verma
Stem cells and development 19 (2), 239-246, 2010
292010
Late passage human fibroblasts induced to pluripotency are capable of directed neuronal differentiation
J Liu, H Sumer, J Leung, K Upton, M Dottori, A Pébay, PJ Verma
Cell transplantation 20 (2), 193-204, 2011
262011
Is somatic retrotransposition a parasitic or symbiotic phenomenon?
KR Upton, JK Baillie, GJ Faulkner
Mobile genetic elements 1 (4), 279-328, 2011
242011
Widespread exaptation of L1 transposons for transcription factor binding in breast cancer
JC Jiang, JA Rothnagel, KR Upton
International Journal of Molecular Sciences 22 (11), 5625, 2021
122021
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model
JC Jiang, JA Rothnagel, KR Upton
Scientific Reports 11 (1), 8083, 2021
82021
A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants
KD Hulme, AC Karawita, C Pegg, MJM Bunte, H Bielefeldt-Ohmann, ...
Elife 10, e61803, 2021
52021
Blood from ‘junk’: the LTR chimeric transcript Pu.2 promotes erythropoiesis
KR Upton, GJ Faulkner
Mobile DNA 5, 1-4, 2014
52014
Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
S Klawitter, NV Fuchs, KR Upton, M Muñoz-Lopez, R Shukla, J Wang, ...
Nature Communications 9, 2018
32018
L1PA2 transposons contribute abundant regulatory sequences in MCF7 breast cancer cell line
JC Jiang, J Rothnagel, K Upton
bioRxiv, 2020.09. 01.276808, 2020
12020
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