Somatic retrotransposition alters the genetic landscape of the human brain JK Baillie, MW Barnett, KR Upton, DJ Gerhardt, TA Richmond, F De Sapio, ... Nature 479 (7374), 534-537, 2011 | 838 | 2011 |
Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma R Shukla, KR Upton, M Muñoz-Lopez, DJ Gerhardt, ME Fisher, T Nguyen, ... Cell 153 (1), 101-111, 2013 | 439 | 2013 |
Ubiquitous L1 mosaicism in hippocampal neurons KR Upton, DJ Gerhardt, JS Jesuadian, SR Richardson, ... Cell 161 (2), 228-239, 2015 | 376 | 2015 |
Extensive somatic L1 retrotransposition in colorectal tumors S Solyom, AD Ewing, EP Rahrmann, T Doucet, HH Nelson, MB Burns, ... Genome research 22 (12), 2328-2338, 2012 | 310 | 2012 |
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells S Klawitter, NV Fuchs, KR Upton, M Munoz-Lopez, R Shukla, J Wang, ... Nature communications 7 (1), 10286, 2016 | 151 | 2016 |
Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus C Pridans, A Raper, GM Davis, J Alves, KA Sauter, L Lefevre, T Regan, ... The Journal of Immunology 201 (9), 2683-2699, 2018 | 125 | 2018 |
The efficient generation of induced pluripotent stem (iPS) cells from adult mouse adipose tissue-derived and neural stem cells PA Tat, H Sumer, KL Jones, K Upton, PJ Verma Cell transplantation 19 (5), 525-536, 2010 | 105 | 2010 |
L1 retrotransposon heterogeneity in ovarian tumor cell evolution THM Nguyen, PE Carreira, FJ Sanchez-Luque, SN Schauer, AC Fagg, ... Cell reports 23 (13), 3730-3740, 2018 | 60 | 2018 |
Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme PE Carreira, AD Ewing, G Li, SN Schauer, KR Upton, AC Fagg, S Morell, ... Mobile DNA 7, 1-14, 2016 | 40 | 2016 |
Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines JC Jiang, KR Upton Mobile DNA 10, 1-14, 2019 | 33 | 2019 |
High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier KD Hulme, L Yan, RJ Marshall, CJ Bloxham, KR Upton, SZ Hasnain, ... Elife 9, e56907, 2020 | 31 | 2020 |
Reprogramming of somatic cells after fusion with induced pluripotent stem cells and nuclear transfer embryonic stem cells H Sumer, KL Jones, J Liu, C Heffernan, PA Tat, KR Upton, PJ Verma Stem cells and development 19 (2), 239-246, 2010 | 29 | 2010 |
Late passage human fibroblasts induced to pluripotency are capable of directed neuronal differentiation J Liu, H Sumer, J Leung, K Upton, M Dottori, A Pébay, PJ Verma Cell transplantation 20 (2), 193-204, 2011 | 26 | 2011 |
Is somatic retrotransposition a parasitic or symbiotic phenomenon? KR Upton, JK Baillie, GJ Faulkner Mobile genetic elements 1 (4), 279-328, 2011 | 24 | 2011 |
Widespread exaptation of L1 transposons for transcription factor binding in breast cancer JC Jiang, JA Rothnagel, KR Upton International Journal of Molecular Sciences 22 (11), 5625, 2021 | 12 | 2021 |
Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model JC Jiang, JA Rothnagel, KR Upton Scientific Reports 11 (1), 8083, 2021 | 8 | 2021 |
A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants KD Hulme, AC Karawita, C Pegg, MJM Bunte, H Bielefeldt-Ohmann, ... Elife 10, e61803, 2021 | 5 | 2021 |
Blood from ‘junk’: the LTR chimeric transcript Pu.2 promotes erythropoiesis KR Upton, GJ Faulkner Mobile DNA 5, 1-4, 2014 | 5 | 2014 |
Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells S Klawitter, NV Fuchs, KR Upton, M Muñoz-Lopez, R Shukla, J Wang, ... Nature Communications 9, 2018 | 3 | 2018 |
L1PA2 transposons contribute abundant regulatory sequences in MCF7 breast cancer cell line JC Jiang, J Rothnagel, K Upton bioRxiv, 2020.09. 01.276808, 2020 | 1 | 2020 |