A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion CL Hansen, E Skordalakes, JM Berger, SR Quake Proceedings of the National Academy of Sciences 99 (26), 16531-16536, 2002 | 881 | 2002 |
Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA NM Belliveau, J Huft, PJC Lin, S Chen, AKK Leung, TJ Leaver, AW Wild, ... Molecular Therapy-Nucleic Acids 1, 2012 | 823 | 2012 |
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat FK Balagaddé, L You, CL Hansen, FH Arnold, SR Quake Science 309 (5731), 137-140, 2005 | 815 | 2005 |
Nucleic acid amplification utilizing microfluidic devices MM Enzelberger, J Liu, SR Quake US Patent 6,960,437, 2005 | 769 | 2005 |
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ... Nature 518 (7539), 422-426, 2015 | 677 | 2015 |
High-throughput microfluidic single-cell RT-qPCR AK White, M VanInsberghe, OI Petriv, M Hamidi, D Sikorski, MA Marra, ... Proceedings of the National Academy of Sciences 108 (34), 13999-14004, 2011 | 585 | 2011 |
The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates BE Jones, PL Brown-Augsburger, KS Corbett, K Westendorf, J Davies, ... Science translational medicine 13 (593), eabf1906, 2021 | 453 | 2021 |
Bottom-up design and synthesis of limit size lipid nanoparticle systems with aqueous and triglyceride cores using millisecond microfluidic mixing IV Zhigaltsev, N Belliveau, I Hafez, AKK Leung, J Huft, C Hansen, ... Langmuir 28 (7), 3633-3640, 2012 | 437 | 2012 |
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ... Cell reports 39 (7), 2022 | 418 | 2022 |
Small but perfectly formed? Successes, challenges, and opportunities for microfluidics in the chemical and biological sciences DT Chiu, AJ Demello, D Di Carlo, PS Doyle, C Hansen, RM Maceiczyk, ... Chem 2 (2), 201-223, 2017 | 413 | 2017 |
Microfluidics in structural biology: smaller, faster… better C Hansen, SR Quake Current opinion in structural biology 13 (5), 538-544, 2003 | 404 | 2003 |
Megapixel digital PCR KA Heyries, C Tropini, M VanInsberghe, C Doolin, OI Petriv, A Singhal, ... Nature methods 8 (8), 649-651, 2011 | 388 | 2011 |
High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays V Lecault, M VanInsberghe, S Sekulovic, DJHF Knapp, S Wohrer, ... Nature methods 8 (7), 581-586, 2011 | 384 | 2011 |
Solving the “world-to-chip” interface problem with a microfluidic matrix J Liu, C Hansen, SR Quake Analytical chemistry 75 (18), 4718-4723, 2003 | 384 | 2003 |
Microfabricated elastomeric valve and pump systems MA Unger, HP Chou, TA Thorsen, A Scherer, SR Quake, MM Enzelberger, ... US Patent 6,899,137, 2005 | 365 | 2005 |
Lipid nanoparticles containing siRNA synthesized by microfluidic mixing exhibit an electron-dense nanostructured core AKK Leung, IM Hafez, S Baoukina, NM Belliveau, IV Zhigaltsev, ... The Journal of Physical Chemistry C 116 (34), 18440-18450, 2012 | 363 | 2012 |
Nucleic acid amplification using microfluidic devices MM Enzelberger, CL Hansen, J Liu, SR Quake, C Ma US Patent 7,833,708, 2010 | 341 | 2010 |
Microfabricated elastomeric valve and pump systems MA Unger, HP Chou, TA Thorsen, A Scherer, SR Quake, J Liu, ML Adams, ... US Patent 6,929,030, 2005 | 329* | 2005 |
High throughput screening of crystallization of materials CL Hansen, SR Quake, JM Berger US Patent 7,195,670, 2007 | 306 | 2007 |
A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities K Leung, H Zahn, T Leaver, KM Konwar, NW Hanson, AP Pagé, CC Lo, ... Proceedings of the National Academy of Sciences 109 (20), 7665-7670, 2012 | 297 | 2012 |