| Biophysics, Pathophysiology and Pharmacology of Ion Channel Gating Pores A Moreau, P Gosselin-Badaroudine, M Chahine Pharmacology of Ion Channels and Channelopathies 5, 53, 2014 | 91 | 2014 |
| Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy A Moreau, P Gosselin-Badaroudine, L Delemotte, ML Klein, M Chahine Journal of General Physiology 145 (2), 93-106, 2015 | 89 | 2015 |
| Gating pore currents and the resting state of Nav1. 4 voltage sensor domains P Gosselin-Badaroudine, L Delemotte, A Moreau, ML Klein, M Chahine Proceedings of the National Academy of Sciences 109 (47), 19250-19255, 2012 | 88 | 2012 |
| Post-translational modifications and diastolic calcium leak associated to the novel RyR2-D3638A mutation lead to CPVT in patient-specific hiPSC-derived cardiomyocytes I Acimovic, MM Refaat, A Moreau, A Salykin, S Reiken, Y Sleiman, ... Journal of clinical medicine 7 (11), 423, 2018 | 52 | 2018 |
| Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents A Moreau, P Gosselin-Badaroudine, M Boutjdir, M Chahine Frontiers in pharmacology 6, 301, 2015 | 51 | 2015 |
| A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy A Moreau, P Gosselin-Badaroudine, A Mercier, B Burger, DI Keller, ... Scientific reports 8 (1), 13804, 2018 | 41 | 2018 |
| Nav1. 5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link? P Gosselin-Badaroudine, A Moreau, M Chahine Channels 8 (1), 90-94, 2014 | 40 | 2014 |
| Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations A Moreau, DI Keller, H Huang, V Fressart, C Schmied, Q Timour, ... Frontiers in Pharmacology 3, 62, 2012 | 39 | 2012 |
| Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides P Gosselin-Badaroudine, A Moreau, L Delemotte, T Cens, C Collet, ... Scientific Reports 5 (1), 12475, 2015 | 31 | 2015 |
| Biophysical, molecular, and pharmacological characterization of voltage-dependent sodium channels from induced pluripotent stem cell-derived cardiomyocytes A Moreau, A Mercier, O Thériault, M Boutjdir, B Burger, DI Keller, ... Canadian Journal of Cardiology 33 (2), 269-278, 2017 | 29 | 2017 |
| Molecular biology and biophysical properties of ion channel gating pores A Moreau, P Gosselin-Badaroudine, M Chahine Quarterly reviews of biophysics 47 (4), 364-388, 2014 | 29 | 2014 |
| Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation A Moreau, AD Krahn, P Gosselin-Badaroudine, GJ Klein, G Christé, ... Frontiers in pharmacology 4, 126, 2013 | 27 | 2013 |
| Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes Y Sleiman, M Souidi, R Kumar, E Yang, F Jaffré, T Zhou, A Bernardin, ... EBioMedicine 60, 2020 | 23 | 2020 |
| A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Nav1.5 Gating Pores A Moreau, M Chahine Frontiers in cardiovascular medicine 5, 139, 2018 | 23 | 2018 |
| Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4 P Gosselin-Badaroudine, A Moreau, L Simard, T Cens, M Rousset, ... Journal of General Physiology 148 (2), 133-145, 2016 | 23 | 2016 |
| Deciphering DSC2 arrhythmogenic cardiomyopathy electrical instability: From ion channels to ECG and tailored drug therapy A Moreau, JB Reisqs, H Delanoe‐Ayari, M Pierre, A Janin, A Deliniere, ... Clinical and translational medicine 11 (3), e319, 2021 | 21 | 2021 |
| Cardiac voltage-gated sodium channel mutations associated with left atrial dysfunction and stroke in children A Moreau, A Janin, G Millat, P Chevalier Ep Europace 20 (10), 1692-1698, 2018 | 20 | 2018 |
| Gating pore currents in sodium channels JR Groome, A Moreau, L Delemotte Voltage-gated Sodium Channels: Structure, Function and Channelopathies, 371-399, 2018 | 17 | 2018 |
| The PPARγ pathway determines electrophysiological remodelling and arrhythmia risks in DSC2 arrhythmogenic cardiomyopathy JB Reisqs, A Moreau, A Charrabi, Y Sleiman, AC Meli, G Millat, V Briand, ... Clinical and Translational Medicine 12 (3), 2022 | 15 | 2022 |
| Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy A Moreau, P Gosselin-Badaroudine, M Chahine Channels 9 (3), 139-144, 2015 | 14 | 2015 |
Mohamed ChahineFull professor, laval UniversityVerified email at phc.ulaval.ca
