Antidepressant drugs act by directly binding to TRKB neurotrophin receptors PC Casarotto, M Girych, SM Fred, V Kovaleva, R Moliner, G Enkavi, ... Cell 184 (5), 1299-1313. e19, 2021 | 525 | 2021 |
Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2 SM Fred, L Laukkanen, CA Brunello, L Vesa, H Göös, I Cardon, R Moliner, ... Journal of Biological Chemistry 294 (48), 18150-18161, 2019 | 47 | 2019 |
Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties J Triebelhorn, I Cardon, K Kuffner, S Bader, T Jahner, K Meindl, ... Molecular Psychiatry 29 (5), 1217-1227, 2024 | 21 | 2024 |
Antidepressants bind to cholesterol-interaction motif of TRKB neurotrophin receptor PC Casarotto, M Girych, SM Fred, R Moliner, G Enkavi, C Biojone, ... BioRxiv 757989, 2020 | 10 | 2020 |
Mitochondrial and Cellular Function in Fibroblasts, Induced Neurons, and Astrocytes Derived from Case Study Patients: Insights into Major Depression as a Mitochondria … I Cardon, S Grobecker, S Kücükoktay, S Bader, T Jahner, C Nothdurfter, ... International Journal of Molecular Sciences 25 (2), 963, 2024 | 8 | 2024 |
Serotonin effects on human iPSC-derived neural cell functions: from mitochondria to depression I Cardon, S Grobecker, F Jenne, T Jahner, R Rupprecht, VM Milenkovic, ... Molecular Psychiatry, 1-12, 2024 | 7 | 2024 |
Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2 SM Fred, L Laukkanen, L Vesa, H Goos, I Cardon, R Moliner, T Maritzen, ... BioRxiv, 591909, 2019 | 2 | 2019 |
A comprehensive functional investigation of the human translocator protein 18 kDa (TSPO) in a novel human neuronal cell knockout model: from molecule to depression C Wetzel, S Bader, T Jahner, A Dörfelt, D Melchner, I Cardon, ... | 1 | 2024 |
Antidepressants act by binding to the transmembrane domain of TRKB receptor PC Casarotto, M Girych, SM Fred, R Moliner, G Enkavi, C Biojone, ... bioRxiv, 757989, 2019 | 1 | 2019 |
A Comprehensive Functional Investigation of the Human Translocator Protein 18 kDa (TSPO) in a Novel Human Neuronal Cell Knockout Model S Bader, T Jahner, A Dörfelt, D Melchner, I Cardon, HI Siegmund, ... International Journal of Molecular Sciences 25 (23), 12882, 2024 | | 2024 |
Bridging depression and mitochondria: functional insights from cellular models in case study patients I Cardon | | 2024 |
Serotonin Effects on Human iPSC-Derived Neural Cell Functions: from Mitochondria to Depression C Wetzel, I Cardon, S Grobecker, F Jenne, T Jahner, R Rupprecht, ... | | 2024 |
Mitochondrial and cellular function in fibroblasts, induced neurons, and astrocytes derived from case study patients: insights into major depression as a mitochondria … C Wetzel, I Cardon, S Grobecker, S Kücükoktay, S Bader, T Jahner, ... | | 2023 |
Mitochondrial and cellular function in fibroblasts and reprogrammed neural cells: insights into major depression as a mitochondria-associated disease C Wetzel, I Cardon, S Grobecker, S Kücükoktay, S Bader, T Jahner, ... | | 2023 |