Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer H Zhang, T Liu, Z Zhang, SH Payne, B Zhang, JE McDermott, JY Zhou, ... Cell 166 (3), 755-765, 2016 | 989 | 2016 |
Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends … DM Merino, LM McShane, D Fabrizio, V Funari, SJ Chen, JR White, ... Journal for Immunotherapy of Cancer 8 (1), 2020 | 440 | 2020 |
TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository Y Zhao, MC Li, MM Konaté, L Chen, B Das, C Karlovich, PM Williams, ... Journal of Translational Medicine 19 (1), 1-15, 2021 | 337 | 2021 |
Proteomic Analysis of Chinese Hamster Ovary (CHO) Cells D Baycin Hizal, DL Tabb, R Chaerkady, L Chen, NE Lewis, H Nagarajan, ... Journal of Proteome Research, 2012 | 202 | 2012 |
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts XY Woo, J Giordano, A Srivastava, ZM Zhao, MW Lloyd, R de Bruijn, ... Nature Genetics 53 (1), 86-99, 2021 | 169 | 2021 |
Gene expression signatures of primary and metastatic uterine leiomyosarcoma B Davidson, VM Abeler, M Førsund, A Holth, Y Yang, Y Kobayashi, ... Human pathology 45 (4), 691-700, 2014 | 146 | 2014 |
ERRγ mediates tamoxifen resistance in novel models of invasive lobular breast cancer RB Riggins, JPJ Lan, U Klimach, A Zwart, LR Cavalli, BR Haddad, L Chen, ... Cancer research 68 (21), 8908-8917, 2008 | 138 | 2008 |
Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project DM Vega, LM Yee, LM McShane, PM Williams, L Chen, T Vilimas, ... Annals of Oncology 32 (12), 1626-1636, 2021 | 127 | 2021 |
Metabolic flux increases glycoprotein sialylation: implications for cell adhesion and cancer metastasis RT Almaraz, Y Tian, R Bhattarcharya, E Tan, SH Chen, MR Dallas, ... Molecular & Cellular Proteomics 11 (7), M112. 017558, 2012 | 123 | 2012 |
Identifying cancer biomarkers by network-constrained support vector machines L Chen, J Xuan, RB Riggins, R Clarke, Y Wang BMC systems biology 5 (1), 161, 2011 | 112 | 2011 |
Clinical Evolution of Epithelial–Mesenchymal Transition in Human Carcinomas T Navas, RJ Kinders, SM Lawrence, KV Ferry-Galow, S Borgel, ... Cancer Research 80 (2), 304-318, 2020 | 94 | 2020 |
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment H Sun, S Cao, RJ Mashl, CK Mo, S Zaccaria, MC Wendl, SR Davies, ... Nature Communications 12 (1), 1-20, 2021 | 92 | 2021 |
Serum fucosylated prostate-specific antigen (PSA) improves the differentiation of aggressive from non-aggressive prostate cancers QK Li, L Chen, MH Ao, JH Chiu, Z Zhang, H Zhang, DW Chan Theranostics 5 (3), 267, 2015 | 82 | 2015 |
Distinct DNA methylation profiles in ovarian serous neoplasms and their implications in ovarian carcinogenesis IM Shih, L Chen, CC Wang, J Gu, B Davidson, L Cope, RJ Kurman, ... American journal of obstetrics and gynecology 203 (6), 584. e1-584. e22, 2010 | 74 | 2010 |
Defining NOTCH3 target genes in ovarian cancer X Chen, MM Thiaville, L Chen, A Stoeck, J Xuan, M Gao, IM Shih, ... Cancer research 72 (9), 2294-2303, 2012 | 69 | 2012 |
Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways X Wu, MS Zahari, B Ma, R Liu, S Renuse, NA Sahasrabuddhe, L Chen, ... Oncotarget 6 (30), 29143, 2015 | 62 | 2015 |
Systematic establishment of robustness and standards in patient-derived xenograft experiments and analysis YA Evrard, A Srivastava, J Randjelovic, JH Doroshow, DA Dean, ... Cancer research 80 (11), 2286-2297, 2020 | 57 | 2020 |
Safety, anti-tumor activity, and biomarker analysis in a phase 1 trial of the once-daily Wee1 inhibitor adavosertib (AZD1775) in patients with advanced solid tumors N Takebe, AR Naqash, GOS Coyne, S Kummar, KT Do, A Bruns, ... Clinical Cancer Research, 2021 | 50 | 2021 |
Identification of PBX1 Target Genes in Cancer Cells by Global Mapping of PBX1 Binding Sites MM Thiaville, A Stoeck, L Chen, RC Wu, L Magnani, J Oidtman, IM Shih, ... PloS one 7 (5), e36054, 2012 | 50 | 2012 |
Identifying protein interaction subnetworks by a bagging Markov random field-based method L Chen, J Xuan, RB Riggins, Y Wang, R Clarke Nucleic Acids Research, 2012 | 49 | 2012 |