| A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair M Babu, N Beloglazova, R Flick, C Graham, T Skarina, B Nocek, ... Molecular microbiology 79 (2), 484-502, 2011 | 357 | 2011 |
| Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction N Beloglazova, R Flick, A Tchigvintsev, G Brown, A Popovic, B Nocek, ... Journal of Biological Chemistry 288 (12), 8101-8110, 2013 | 268 | 2013 |
| Biochemical and structural insights into enzymatic depolymerization of polylactic acid and other polyesters by microbial carboxylesterases M Hajighasemi, BP Nocek, A Tchigvintsev, G Brown, R Flick, X Xu, H Cui, ... Biomacromolecules 17 (6), 2027-2039, 2016 | 162 | 2016 |
| Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria B Nocek, S Kochinyan, M Proudfoot, G Brown, E Evdokimova, J Osipiuk, ... Proceedings of the National Academy of Sciences 105 (46), 17730-17735, 2008 | 161 | 2008 |
| Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila ML Urbanus, AT Quaile, PJ Stogios, M Morar, C Rao, R Di Leo, ... Molecular systems biology 12 (12), 893, 2016 | 139 | 2016 |
| Determinants and prediction of esterase substrate promiscuity patterns M Martínez-Martínez, C Coscolín, G Santiago, J Chow, PJ Stogios, ... ACS chemical biology 13 (1), 225-234, 2017 | 136 | 2017 |
| Large-scale evaluation of protein reductive methylation for improving protein crystallization Y Kim, P Quartey, H Li, L Volkart, C Hatzos, C Chang, B Nocek, M Cuff, ... Nature methods 5 (10), 853-854, 2008 | 118 | 2008 |
| Functional diversity of haloacid dehalogenase superfamily phosphatases from Saccharomyces cerevisiae: biochemical, structural, and evolutionary insights E Kuznetsova, B Nocek, G Brown, KS Makarova, R Flick, YI Wolf, ... Journal of Biological Chemistry 290 (30), 18678-18698, 2015 | 107 | 2015 |
| Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families A Popovic, T Hai, A Tchigvintsev, M Hajighasemi, B Nocek, ... Scientific reports 7 (1), 44103, 2017 | 98 | 2017 |
| Exploring bacterial carboxylate reductases for the reduction of bifunctional carboxylic acids AN Khusnutdinova, R Flick, A Popovic, G Brown, A Tchigvintsev, B Nocek, ... Biotechnology journal 12 (11), 1600751, 2017 | 90 | 2017 |
| Screening and characterization of novel polyesterases from environmental metagenomes with high hydrolytic activity against synthetic polyesters M Hajighasemi, A Tchigvintsev, B Nocek, R Flick, A Popovic, T Hai, ... Environmental Science & Technology 52 (21), 12388-12401, 2018 | 87 | 2018 |
| Structural basis for catalysis by the mono-and dimetalated forms of the dapE-encoded N-succinyl-L, L-diaminopimelic acid desuccinylase BP Nocek, DM Gillner, Y Fan, RC Holz, A Joachimiak Journal of molecular biology 397 (3), 617-626, 2010 | 78 | 2010 |
| Differential stabilities and sequence-dependent base pair opening dynamics of Watson–Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine MW Szulik, PS Pallan, B Nocek, M Voehler, S Banerjee, S Brooks, ... Biochemistry 54 (5), 1294-1305, 2015 | 76 | 2015 |
| Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus S Lemak, N Beloglazova, B Nocek, T Skarina, R Flick, G Brown, ... Journal of the American Chemical Society 135 (46), 17476-17487, 2013 | 74 | 2013 |
| Structural insights into substrate selectivity and activity of bacterial polyphosphate kinases BP Nocek, AN Khusnutdinova, M Ruszkowski, R Flick, M Burda, ... ACS Catalysis 8 (11), 10746-10760, 2018 | 73 | 2018 |
| Structural and evolutionary relationships of “AT-less” type I polyketide synthase ketosynthases JR Lohman, M Ma, J Osipiuk, B Nocek, Y Kim, C Chang, M Cuff, J Mack, ... Proceedings of the National Academy of Sciences 112 (41), 12693-12698, 2015 | 68 | 2015 |
| Crystal structures of δ1-pyrroline-5-carboxylate reductase from human pathogens Neisseria meningitides and Streptococcus pyogenes B Nocek, C Chang, H Li, L Lezondra, D Holzle, F Collart, A Joachimiak Journal of molecular biology 354 (1), 91-106, 2005 | 67 | 2005 |
| Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases S Vassiliou, E Weglarz-Tomczak, Ł Berlicki, M Pawełczak, B Nocek, ... Journal of medicinal chemistry 57 (19), 8140-8151, 2014 | 62 | 2014 |
| Molecular characterization of LubX: functional divergence of the U-Box fold by Legionella pneumophila AT Quaile, ML Urbanus, PJ Stogios, B Nocek, T Skarina, AW Ensminger, ... Structure 23 (8), 1459-1469, 2015 | 60 | 2015 |
| A family of metal-dependent phosphatases implicated in metabolite damage-control L Huang, A Khusnutdinova, B Nocek, G Brown, X Xu, H Cui, P Petit, ... Nature Chemical Biology 12 (8), 621-627, 2016 | 59 | 2016 |
