| Seipin facilitates triglyceride flow to lipid droplet and counteracts droplet ripening via endoplasmic reticulum contact VT Salo, S Li, H Vihinen, M Hölttä-Vuori, A Szkalisity, P Horvath, ... Developmental cell 50 (4), 478-493. e9, 2019 | 205 | 2019 |
| Caveolins and cellular cholesterol balance E Ikonen, RG Parton Traffic 1 (3), 212-217, 2000 | 193 | 2000 |
| The beta‐amyloid domain is essential for axonal sorting of amyloid precursor protein. PJ Tienari, B De Strooper, E Ikonen, M Simons, A Weidemann, C Czech, ... The EMBO journal 15 (19), 5218-5229, 1996 | 191 | 1996 |
| An efficient auxin-inducible degron system with low basal degradation in human cells S Li, X Prasanna, VT Salo, I Vattulainen, E Ikonen Nature methods 16 (9), 866-869, 2019 | 179 | 2019 |
| Association of tamoxifen resistance and lipid reprogramming in breast cancer S Hultsch, M Kankainen, L Paavolainen, RM Kovanen, E Ikonen, ... BMC cancer 18, 1-14, 2018 | 179 | 2018 |
| Significance of sterol structural specificity: desmosterol cannot replace cholesterol in lipid rafts S Vainio, M Jansen, M Koivusalo, T Rog, M Karttunen, I Vattulainen, ... Journal of Biological Chemistry 281 (1), 348-355, 2006 | 173 | 2006 |
| Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages E Rigamonti, L Helin, S Lestavel, AL Mutka, M Lepore, C Fontaine, ... Circulation research 97 (7), 682-689, 2005 | 169 | 2005 |
| Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export S Heybrock, K Kanerva, Y Meng, C Ing, A Liang, ZJ Xiong, X Weng, ... Nature communications 10 (1), 3521, 2019 | 163 | 2019 |
| Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease V Võikar, H Rauvala, E Ikonen Behavioural brain research 132 (1), 1-10, 2002 | 163 | 2002 |
| Convenient and quantitative determination of the frequency of a mutant allele using solid-phase minisequencing: application to aspartylglucosaminuria in Finland AC Syvänen, E Ikonen, T Manninen, M Bengtström, H Söderlund, P Aula, ... Genomics 12 (3), 590-595, 1992 | 163 | 1992 |
| Intracellular routing of human amyloid protein precursor: axonal delivery followed by transport to the dendrites M Simons, E Ikonen, PJ Tienari, A Cid‐Arregui, U Mönning, K Beyreuther, ... Journal of neuroscience research 41 (1), 121-128, 1995 | 161 | 1995 |
| Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane S Lusa, TS Blom, EL Eskelinen, E Kuismanen, JE Månsson, K Simons, ... Journal of cell science 114 (10), 1893-1900, 2001 | 156 | 2001 |
| Desmosterol and DHCR24: unexpected new directions for a terminal step in cholesterol synthesis EJ Zerenturk, LJ Sharpe, E Ikonen, AJ Brown Progress in lipid research 52 (4), 666-680, 2013 | 151 | 2013 |
| Modulation of cellular cholesterol transport and homeostasis by Rab11 M Hölttä-Vuori, K Tanhuanpää, W Mobius, P Somerharju, E Ikonen Molecular Biology of the Cell 13 (9), 3107-3122, 2002 | 150 | 2002 |
| Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids PK Luukkonen, A Nick, M Hölttä-Vuori, C Thiele, E Isokuortti, ... JCI insight 4 (16), 2019 | 148 | 2019 |
| Aspartylglucosaminuria: cDNA encoding human aspartylglucosaminidase and the missense mutation causing the disease. E Ikonen, M Baumann, K Grön, AC Syvänen, N Enomaa, R Halila, P Aula, ... The EMBO Journal 10 (1), 51-58, 1991 | 140 | 1991 |
| PNPLA3 mediates hepatocyte triacylglycerol remodeling [S] H Ruhanen, J Perttilä, M Hölttä-Vuori, Y Zhou, H Yki-Järvinen, E Ikonen, ... Journal of lipid research 55 (4), 739-746, 2014 | 139 | 2014 |
| Lipid droplet nucleation AR Thiam, E Ikonen Trends in Cell Biology 31 (2), 108-118, 2021 | 128 | 2021 |
| Cellular pathology of Niemann–Pick type C disease E Ikonen, M Hölttä-Vuori Seminars in cell & developmental biology 15 (4), 445-454, 2004 | 128 | 2004 |
| Role of cholesterol in developing T‐tubules: analogous mechanisms for T‐tubule and caveolae biogenesis AJ Carozzi, E Ikonen, MR Lindsay, RG Parton Traffic 1 (4), 326-341, 2000 | 128 | 2000 |