Geroscience: linking aging to chronic disease BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ... Cell 159 (4), 709-713, 2014 | 2375 | 2014 |
Extension of life-span with superoxide dismutase/catalase mimetics S Melov, J Ravenscroft, S Malik, MS Gill, DW Walker, PE Clayton, ... Science 289 (5484), 1567-1569, 2000 | 1217 | 2000 |
From discoveries in ageing research to therapeutics for healthy ageing J Campisi, P Kapahi, GJ Lithgow, S Melov, JC Newman, E Verdin Nature 571 (7764), 183-192, 2019 | 1141 | 2019 |
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. GJ Lithgow, TM White, S Melov, TE Johnson Proceedings of the National Academy of Sciences 92 (16), 7540-7544, 1995 | 1070 | 1995 |
Long live FOXO: unraveling the role of FOXO proteins in aging and longevity R Martins, GJ Lithgow, W Link Aging cell 15 (2), 196-207, 2016 | 737 | 2016 |
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans KZ Pan, JE Palter, AN Rogers, A Olsen, D Chen, GJ Lithgow, P Kapahi Aging cell 6 (1), 111-119, 2007 | 589 | 2007 |
MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8 D Bhaumik, GK Scott, S Schokrpur, CK Patil, AV Orjalo, F Rodier, ... Aging 1 (4), 402, 2009 | 585 | 2009 |
Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan S Alavez, MC Vantipalli, DJS Zucker, IM Klang, GJ Lithgow Nature 472 (7342), 226-229, 2011 | 426 | 2011 |
Lifespan extension in C. elegans by a molecular chaperone dependent upon insulin‐like signals GA Walker, GJ Lithgow Aging cell 2 (2), 131-139, 2003 | 406 | 2003 |
Longevity and heavy metal resistance in daf‐2 and age‐1 long‐lived mutants of Caenorhabditis elegans D Barsyte, DA Lovejoy, GJ Lithgow The FASEB Journal 15 (3), 627-634, 2001 | 364 | 2001 |
Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice AA Shahmirzadi, D Edgar, CY Liao, YM Hsu, M Lucanic, AA Shahmirzadi, ... Cell metabolism 32 (3), 447-456. e6, 2020 | 314 | 2020 |
Thermotolerance of a long-lived mutant of Caenorhabditis elegans GJ Lithgow, TM White, DA Hinerfeld, TE Johnson Journal of gerontology 49 (6), B270-B276, 1994 | 280 | 1994 |
Stress biology and aging mechanisms: toward understanding the deep connection between adaptation to stress and longevity ES Epel, GJ Lithgow Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2014 | 269 | 2014 |
Stress resistance as a determinate of C. elegans lifespan GJ Lithgow, GA Walker Mechanisms of ageing and development 123 (7), 765-771, 2002 | 268 | 2002 |
Evolution of lifespan in C. elegans DW Walker, G McColl, NL Jenkins, J Harris, GJ Lithgow Nature 405 (6784), 296-297, 2000 | 250 | 2000 |
Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans G McColl, DW Killilea, AE Hubbard, MC Vantipalli, S Melov, GJ Lithgow Journal of Biological Chemistry 283 (1), 350-357, 2008 | 242 | 2008 |
Taurine deficiency as a driver of aging P Singh, K Gollapalli, S Mangiola, D Schranner, MA Yusuf, M Chamoli, ... Science 380 (6649), eabn9257, 2023 | 228 | 2023 |
Mortality rates in a genetically heterogeneous population of Caenorhabditis elegans A Brooks, GJ Lithgow, TE Johnson Science 263 (5147), 668-671, 1994 | 227 | 1994 |
Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods D GuhaThakurta, L Palomar, GD Stormo, P Tedesco, TE Johnson, ... Genome research 12 (5), 701-712, 2002 | 207 | 2002 |
Fitness cost of extended lifespan in Caenorhabditis elegans NL Jenkins, G McColl, GJ Lithgow Proceedings of the Royal Society of London. Series B: Biological Sciences …, 2004 | 201 | 2004 |