The P2X7 receptor in inflammatory diseases: angel or demon? LEB Savio, P de Andrade Mello, CGA Da Silva, R Coutinho-Silva Frontiers in pharmacology 9, 52, 2018 | 433 | 2018 |
CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury LEB Savio, P de Andrade Mello, VR Figliuolo, TF de Avelar Almeida, ... Journal of hepatology 67 (4), 716-726, 2017 | 160 | 2017 |
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice FL Fontes-Dantas, GG Fernandes, EG Gutman, EV De Lima, LS Antonio, ... Cell reports 42 (3), 2023 | 114 | 2023 |
Multifaceted effects of extracellular adenosine triphosphate and adenosine in the tumor–host interaction and therapeutic perspectives P de Andrade Mello, R Coutinho-Silva, LEB Savio Frontiers in immunology 8, 1526, 2017 | 105 | 2017 |
Secondary metabolism in micropropagated Hypericum perforatum L. grown in non-aerated liquid medium LEB Savio, LV Astarita, ER Santarém Plant cell, tissue and organ culture (pctoc) 108, 465-472, 2012 | 100 | 2012 |
The role of P2X7 receptor in infectious inflammatory diseases and the influence of ectonucleotidases A Morandini, L Savio, R Coutinho-Silva Biomedical journal 37 (4), 169, 2014 | 98 | 2014 |
Mild hyperhomocysteinemia increases brain acetylcholinesterase and proinflammatory cytokine levels in different tissues EBS Scherer, SO Loureiro, FC Vuaden, AA da Cunha, F Schmitz, ... Molecular neurobiology 50, 589-596, 2014 | 72 | 2014 |
Purinergic signaling in the modulation of redox biology LEB Savio, R Leite-Aguiar, VS Alves, R Coutinho-Silva, ATS Wyse Redox Biology 47, 102137, 2021 | 66 | 2021 |
P2X7 receptor signaling contributes to sepsis-associated brain dysfunction LEB Savio, MGJ Andrade, P de Andrade Mello, PT Santana, ... Molecular Neurobiology 54, 6459-6470, 2017 | 61 | 2017 |
P2X7 receptor promotes intestinal inflammation in chemically induced colitis and triggers death of mucosal regulatory T cells VR Figliuolo, LEB Savio, H Safya, H Nanini, C Bernardazzi, A Abalo, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (6 …, 2017 | 60 | 2017 |
The role of NOD-like receptors in innate immunity CLC Almeida-da-Silva, LEB Savio, R Coutinho-Silva, DM Ojcius Frontiers in Immunology 14, 1122586, 2023 | 58 | 2023 |
Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death P de Andrade Mello, S Bian, LEB Savio, H Zhang, J Zhang, W Junger, ... Oncotarget 8 (40), 67254, 2017 | 55 | 2017 |
Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish LEB Savio, FC Vuaden, AL Piato, CD Bonan, ATS Wyse Progress in Neuro-Psychopharmacology and Biological Psychiatry 36 (2), 258-263, 2012 | 50 | 2012 |
Purinergic signaling in infectious diseases of the central nervous system VS Alves, R Leite-Aguiar, JP da Silva, R Coutinho-Silva, LEB Savio Brain, Behavior, and Immunity 89, 480-490, 2020 | 41 | 2020 |
The role of the P2X7 receptor in murine cutaneous leishmaniasis: aspects of inflammation and parasite control VR Figliuolo, SP Chaves, LEB Savio, MLP Thorstenberg, ... Purinergic Signalling 13, 143-152, 2017 | 38 | 2017 |
Inflammatory early events associated to the role of P2X7 receptor in acute murine toxoplasmosis G Corrêa, C de Almeida Lindenberg, AC de Abreu Moreira-Souza, ... Immunobiology 222 (4), 676-683, 2017 | 37 | 2017 |
Long-term methionine exposure induces memory impairment on inhibitory avoidance task and alters acetylcholinesterase activity and expression in zebrafish (Danio rerio) FC Vuaden, LEB Savio, AL Piato, TC Pereira, MR Vianna, MR Bogo, ... Neurochemical research 37, 1545-1553, 2012 | 31 | 2012 |
Immunomodulatory effects of P2X7 receptor in intracellular parasite infections LEB Savio, R Coutinho-Silva Current Opinion in Pharmacology 47, 53-58, 2019 | 30 | 2019 |
The effect of exercise on the oxidative stress induced by experimental lung injury MJ da Cunha, AA da Cunha, GK Ferreira, ME Baladão, LEB Savio, ... Life sciences 92 (3), 218-227, 2013 | 29 | 2013 |
Innate immune memory mediates increased susceptibility to Alzheimer’s disease-like pathology in sepsis surviving mice VL De Sousa, SB Araújo, LM Antonio, M Silva-Queiroz, LC Colodeti, ... Brain, Behavior, and Immunity 95, 287-298, 2021 | 28 | 2021 |