Articles with public access mandates - Zhiqing LiuLearn more
Not available anywhere: 7
Discovery of novel 2, 4-diarylaminopyrimidine analogues (DAAPalogues) showing potent inhibitory activities against both wild-type and mutant ALK kinases
Z Song, Y Yang, Z Liu, X Peng, J Guo, X Yang, K Wu, J Ai, J Ding, M Geng, ...
Journal of medicinal chemistry 58 (1), 197-211, 2015
Mandates: National Natural Science Foundation of China
Small-molecule inhibitors targeting the canonical WNT signaling pathway for the treatment of cancer
Z Liu, P Wang, EA Wold, Q Song, C Zhao, C Wang, J Zhou
Journal of medicinal chemistry 64 (8), 4257-4288, 2021
Mandates: US National Institutes of Health, National Natural Science Foundation of China
Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors
Z Liu, X Yue, Z Song, X Peng, J Guo, Y Ji, Z Cheng, J Ding, J Ai, M Geng, ...
European journal of medicinal chemistry 86, 438-448, 2014
Mandates: National Natural Science Foundation of China
Discovery of quinazolin-4 (3h)-one derivatives as novel ache inhibitors with anti-inflammatory activities
L Lv, M Maimaitiming, Y Huang, J Yang, S Chen, Y Sun, X Zhang, X Li, ...
European Journal of Medicinal Chemistry 254, 115346, 2023
Mandates: National Natural Science Foundation of China
Structure-based design and characterization of the highly potent and selective covalent inhibitors targeting the lysine methyltransferases G9a/GLP
Z Feng, C Yang, Y Zhang, H Li, W Fang, J Wang, Y Nie, CY Wang, Z Liu, ...
Journal of Medicinal Chemistry 66 (12), 8086-8102, 2023
Mandates: National Natural Science Foundation of China
Scaffold repurposing of fendiline: Identification of potent KRAS plasma membrane localization inhibitors
P Wang, D van der Hoeven, N Ye, H Chen, Z Liu, X Ma, D Montufar-Solis, ...
European journal of medicinal chemistry 217, 113381, 2021
Mandates: US National Institutes of Health, National Natural Science Foundation of …
Structural optimization of Imidazo [1, 2-a] pyridine derivatives for the treatment of gastric cancer via STAT3 signaling pathway
H Li, S Ouyang, Y Zhang, K Peng, W Fang, Z Liu, CY Wang, X Zhang, ...
European Journal of Medicinal Chemistry 244, 114858, 2022
Mandates: National Natural Science Foundation of China
Available somewhere: 28
Drug discovery targeting bromodomain-containing protein 4
Z Liu, P Wang, H Chen, EA Wold, B Tian, AR Brasier, J Zhou
Journal of medicinal chemistry 60 (11), 4533-4558, 2017
Mandates: US Department of Defense, US National Institutes of Health
Direct activation of Bax protein for cancer therapy
Z Liu, Y Ding, N Ye, C Wild, H Chen, J Zhou
Medicinal research reviews 36 (2), 313-341, 2016
Mandates: US National Institutes of Health
Discovery and development of natural product oridonin-inspired anticancer agents
Y Ding, C Ding, N Ye, Z Liu, EA Wold, H Chen, C Wild, Q Shen, J Zhou
European journal of medicinal chemistry 122, 102-117, 2016
Mandates: US National Institutes of Health
Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV
Q Niu, Z Liu, E Alamer, X Fan, H Chen, J Endsley, BB Gelman, B Tian, ...
The Journal of clinical investigation 129 (8), 3361-3373, 2019
Mandates: US Department of Defense, US National Institutes of Health
Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation
Z Liu, B Tian, H Chen, P Wang, AR Brasier, J Zhou
European journal of medicinal chemistry 151, 450-461, 2018
Mandates: US National Institutes of Health
Discovery of orally bioavailable chromone derivatives as potent and selective BRD4 inhibitors: scaffold hopping, optimization, and pharmacological evaluation
Z Liu, H Chen, P Wang, Y Li, EA Wold, PG Leonard, S Joseph, AR Brasier, ...
Journal of medicinal chemistry 63 (10), 5242-5256, 2020
Mandates: US National Institutes of Health
BH4 domain of Bcl-2 as a novel target for cancer therapy
Z Liu, C Wild, Y Ding, N Ye, H Chen, EA Wold, J Zhou
Drug discovery today 21 (6), 989-996, 2016
Mandates: US National Institutes of Health
Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling
B Tian, K Hosoki, Z Liu, J Yang, Y Zhao, H Sun, J Zhou, E Rytting, ...
Journal of Allergy and Clinical Immunology 143 (4), 1380-1394. e9, 2019
Mandates: US National Science Foundation, US National Institutes of Health
Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets
P Wang, Z Liu, H Chen, N Ye, X Cheng, J Zhou
Bioorganic & medicinal chemistry letters 27 (8), 1633-1639, 2017
Mandates: US National Institutes of Health
Efficacy of novel highly specific bromodomain-containing protein 4 inhibitors in innate inflammation–driven airway remodeling
B Tian, Z Liu, J Litvinov, R Maroto, M Jamaluddin, E Rytting, I Patrikeev, ...
American journal of respiratory cell and molecular biology 60 (1), 68-83, 2019
Mandates: US National Science Foundation, US National Institutes of Health
Structure–Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N′-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange …
N Ye, Y Zhu, H Chen, Z Liu, FC Mei, C Wild, H Chen, X Cheng, J Zhou
Journal of medicinal chemistry 58 (15), 6033-6047, 2015
Mandates: US National Institutes of Health
Selective antagonists of the bronchiolar epithelial NF-κB-bromodomain-containing protein 4 pathway in viral-induced airway inflammation
B Tian, Z Liu, J Yang, H Sun, Y Zhao, M Wakamiya, H Chen, E Rytting, ...
Cell reports 23 (4), 1138-1151, 2018
Mandates: US National Science Foundation, US National Institutes of Health
Regio-and stereospecific synthesis of oridonin D-ring aziridinated analogues for the treatment of triple-negative breast cancer via mediated irreversible covalent warheads
Y Ding, D Li, C Ding, P Wang, Z Liu, EA Wold, N Ye, H Chen, MA White, ...
Journal of medicinal chemistry 61 (7), 2737-2752, 2018
Mandates: US Department of Defense, US National Institutes of Health
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