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Marscha Hirschi
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Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms
A Aartsma-Rus, L Van Vliet, M Hirschi, AAM Janson, H Heemskerk, ...
Molecular Therapy 17 (3), 548-553, 2009
2412009
Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein …
S Eathiraj, R Palma, E Volckova, M Hirschi, DS France, MA Ashwell, ...
Journal of Biological Chemistry 286 (23), 20666-20676, 2011
1682011
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3
M Hirschi, MA Herzik Jr, J Wie, Y Suo, WF Borschel, D Ren, GC Lander, ...
Nature 550 (7676), 411, 2017
1382017
Conformational ensemble of the human TRPV3 ion channel
L Zubcevic, MA Herzik, M Wu, WF Borschel, M Hirschi, AS Song, ...
Nature communications 9 (1), 4773, 2018
1182018
A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited Kinases discovery of atp-independent inhibitors of fibroblast growth factor receptor
S Eathiraj, R Palma, M Hirschi, E Volckova, E Nakuci, J Castro, CR Chen, ...
Journal of Biological Chemistry 286 (23), 20677-20687, 2011
772011
Visualizing multistep elevator-like transitions of a nucleoside transporter
M Hirschi, ZL Johnson, SY Lee
Nature 545 (7652), 66, 2017
602017
Structural and Functional Studies of Nucleoside Transporters
M Hirschi
Duke University, 2017
12017
Discovery of a Novel Mode of Protein Kinase Inhibition Characterized by the Mesenchymal-epithelial Transition Factor (c-Met) Protein Autophosphorylation by ARQ 197
S Eathiraj, R Palma, E Volckova, M Hirschi, D France, M Ashwell, T Chan
Journal of Biological Chemistry 286 (BNL--97410-2012-JA), 2011
2011
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