Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms A Aartsma-Rus, L Van Vliet, M Hirschi, AAM Janson, H Heemskerk, ... Molecular Therapy 17 (3), 548-553, 2009 | 241 | 2009 |
Discovery of a novel mode of protein kinase inhibition characterized by the mechanism of inhibition of human mesenchymal-epithelial transition factor (c-Met) protein … S Eathiraj, R Palma, E Volckova, M Hirschi, DS France, MA Ashwell, ... Journal of Biological Chemistry 286 (23), 20666-20676, 2011 | 168 | 2011 |
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3 M Hirschi, MA Herzik Jr, J Wie, Y Suo, WF Borschel, D Ren, GC Lander, ... Nature 550 (7676), 411, 2017 | 138 | 2017 |
Conformational ensemble of the human TRPV3 ion channel L Zubcevic, MA Herzik, M Wu, WF Borschel, M Hirschi, AS Song, ... Nature communications 9 (1), 4773, 2018 | 118 | 2018 |
A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited Kinases discovery of atp-independent inhibitors of fibroblast growth factor receptor S Eathiraj, R Palma, M Hirschi, E Volckova, E Nakuci, J Castro, CR Chen, ... Journal of Biological Chemistry 286 (23), 20677-20687, 2011 | 77 | 2011 |
Visualizing multistep elevator-like transitions of a nucleoside transporter M Hirschi, ZL Johnson, SY Lee Nature 545 (7652), 66, 2017 | 60 | 2017 |
Structural and Functional Studies of Nucleoside Transporters M Hirschi Duke University, 2017 | 1 | 2017 |
Discovery of a Novel Mode of Protein Kinase Inhibition Characterized by the Mesenchymal-epithelial Transition Factor (c-Met) Protein Autophosphorylation by ARQ 197 S Eathiraj, R Palma, E Volckova, M Hirschi, D France, M Ashwell, T Chan Journal of Biological Chemistry 286 (BNL--97410-2012-JA), 2011 | | 2011 |