| Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer APDA Bom, LP Rangel, DCF Costa, GAP de Oliveira, D Sanches, ... Journal of Biological Chemistry 287 (33), 28152-28162, 2012 | 323 | 2012 |
| DNA converts cellular prion protein into the β-sheet conformation and inhibits prion peptide aggregation Y Cordeiro, F Machado, L Juliano, MA Juliano, RR Brentani, D Foguel, ... Journal of Biological Chemistry 276 (52), 49400-49409, 2001 | 258 | 2001 |
| Fibrillar aggregates of the tumor suppressor p53 core domain D Ishimaru, LR Andrade, LSP Teixeira, PA Quesado, LM Maiolino, ... Biochemistry 42 (30), 9022-9027, 2003 | 218 | 2003 |
| Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins JL Silva, TCRG Vieira, MPB Gomes, APA Bom, LMTR Lima, MS Freitas, ... Accounts of chemical research 43 (2), 271-279, 2010 | 136 | 2010 |
| Intriguing nucleic-acid-binding features of mammalian prion protein JL Silva, LMTR Lima, D Foguel, Y Cordeiro Trends in biochemical sciences 33 (3), 132-140, 2008 | 122 | 2008 |
| Hydration and packing effects on prion folding and β-sheet conversion: High pressure spectroscopy and pressure perturbation calorimetry studies Y Cordeiro, J Kraineva, R Ravindra, LMTR Lima, MPB Gomes, D Foguel, ... Journal of Biological Chemistry 279 (31), 32354-32359, 2004 | 114 | 2004 |
| Structural insights into the interaction between prion protein and nucleic acid LMTR Lima, Y Cordeiro, LW Tinoco, AF Marques, CLP Oliveira, ... Biochemistry 45 (30), 9180-9187, 2006 | 90 | 2006 |
| Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells MPB Gomes, TA Millen, PS Ferreira, NLC e Silva, TCRG Vieira, ... Journal of Biological Chemistry 283 (28), 19616-19625, 2008 | 88 | 2008 |
| Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor JL Silva, LP Rangel, DCF Costa, Y Cordeiro, CV De Moura Gallo Bioscience reports 33 (4), e00054, 2013 | 82 | 2013 |
| Stability and structural changes of horseradish peroxidase: Microwave versus conventional heating treatment LC Lopes, MTM Barreto, KM Goncalves, HM Alvarez, MF Heredia, ... Enzyme and Microbial Technology 69, 10-18, 2015 | 77 | 2015 |
| Pressure-induced formation of inactive triple-shelled rotavirus particles is associated with changes in the spike protein VP4 L Pontes, Y Cordeiro, V Giongo, M Villas-Boas, A Barreto, JR Araújo, ... Journal of Molecular Biology 307 (5), 1171-1179, 2001 | 76 | 2001 |
| Modulation of prion protein oligomerization, aggregation, and β-sheet conversion by 4, 4′-dianilino-1, 1′-binaphthyl-5, 5′-sulfonate (bis-ANS) Y Cordeiro, LMTR Lima, MPB Gomes, D Foguel, JL Silva Journal of Biological Chemistry 279 (7), 5346-5352, 2004 | 75 | 2004 |
| Green tea epigallocatechin-3-gallate (EGCG) targeting protein misfolding in drug discovery for neurodegenerative diseases PB Gonçalves, ACR Sodero, Y Cordeiro Biomolecules 11 (5), 767, 2021 | 73 | 2021 |
| The amino-terminal PrP domain is crucial to modulate prion misfolding and aggregation Y Cordeiro, J Kraineva, MPB Gomes, MH Lopes, VR Martins, LMTR Lima, ... Biophysical journal 89 (4), 2667-2676, 2005 | 73 | 2005 |
| The “Jekyll and Hyde” actions of nucleic acids on the prion-like aggregation of proteins JL Silva, Y Cordeiro Journal of Biological Chemistry 291 (30), 15482-15490, 2016 | 72 | 2016 |
| The p53 core domain is a molten globule at low pH: functional implications of a partially unfolded structure APDA Bom, MS Freitas, FS Moreira, D Ferraz, D Sanches, AMO Gomes, ... Journal of Biological Chemistry 285 (4), 2857-2866, 2010 | 72 | 2010 |
| Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands EC Petronilho, MM Pedrote, MA Marques, YM Passos, MF Mota, ... Chemical science 12 (21), 7334-7349, 2021 | 71 | 2021 |
| Heparin binding confers prion stability and impairs its aggregation TCRG Vieira, Y Cordeiro, B Caughey, JL Silva The FASEB Journal 28 (6), 2667, 2014 | 71 | 2014 |
| Cognate DNA stabilizes the tumor suppressor p53 and prevents misfolding and aggregation D Ishimaru, APD Ano Bom, LMTR Lima, PA Quesado, MFC Oyama, ... Biochemistry 48 (26), 6126-6135, 2009 | 71 | 2009 |
| Liquid-liquid phase transitions and amyloid aggregation in proteins related to cancer and neurodegenerative diseases GAP de Oliveira, Y Cordeiro, JL Silva, TCRG Vieira Advances in protein chemistry and structural biology 118, 289-331, 2019 | 65 | 2019 |
Jerson L. SilvaProfessor of Biochemistry, Universidade Federal do Rio de JaneiroVerified email at bioqmed.ufrj.br
