| Immune checkpoint inhibitors: basics and challenges B Li, HL Chan, P Chen Current medicinal chemistry 26 (17), 3009-3025, 2019 | 440 | 2019 |
| Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system X Wang, H Fan, Z Ying, B Li, H Wang, G Wang Neuroscience letters 469 (1), 112-116, 2010 | 250 | 2010 |
| Parkin mono-ubiquitinates Bcl-2 and regulates autophagy D Chen, F Gao, B Li, H Wang, Y Xu, C Zhu, G Wang Journal of Biological Chemistry 285 (49), 38214-38223, 2010 | 188 | 2010 |
| The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers J Long, B Li, J Rodriguez-Blanco, C Pastori, CH Volmar, C Wahlestedt, ... Journal of Biological Chemistry 289 (51), 35494-35502, 2014 | 125 | 2014 |
| Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases B Li, Q Hu, H Wang, N Man, H Ren, L Wen, N Nukina, E Fei, G Wang Cell Death & Differentiation 17 (11), 1773-1784, 2010 | 109 | 2010 |
| Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma Z Wang, TG Da Silva, K Jin, X Han, P Ranganathan, X Zhu, ... Cancer research 74 (21), 6364-6374, 2014 | 103 | 2014 |
| DJ-1, a cancer and Parkinson’s disease associated protein, regulates autophagy through JNK pathway in cancer cells H Ren, K Fu, C Mu, B Li, D Wang, G Wang Cancer letters 297 (1), 101-108, 2010 | 100 | 2010 |
| Pyrvinium attenuates Hedgehog signaling downstream of smoothened B Li, DL Fei, CA Flaveny, N Dahmane, V Baubet, Z Wang, F Bai, XH Pei, ... Cancer research 74 (17), 4811-4821, 2014 | 88 | 2014 |
| APC inhibits ligand-independent Wnt signaling by the clathrin endocytic pathway K Saito-Diaz, H Benchabane, A Tiwari, A Tian, B Li, JJ Thompson, ... Developmental cell 44 (5), 566-581. e8, 2018 | 84 | 2018 |
| Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis B Li, CA Flaveny, C Giambelli, DL Fei, L Han, BI Hang, F Bai, XH Pei, ... PloS one 9 (7), e101969, 2014 | 73 | 2014 |
| Opioids impair intestinal epithelial repair in HIV-infected humanized mice J Meng, S Banerjee, L Zhang, G Sindberg, S Moidunny, B Li, DJ Robbins, ... Frontiers in immunology 10, 2999, 2020 | 57 | 2020 |
| Gambogenic acid kills lung cancer cells through aberrant autophagy W Mei, C Dong, C Hui, L Bin, Y Fenggen, S Jingjing, P Cheng, S Meiling, ... PLoS One 9 (1), e83604, 2014 | 57 | 2014 |
| The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins P Wang, B Li, L Zhou, E Fei, G Wang Neuroscience 190, 43-55, 2011 | 55 | 2011 |
| Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors B Li, D Orton, LR Neitzel, L Astudillo, C Shen, J Long, X Chen, ... Science signaling 10 (485), eaak9916, 2017 | 41 | 2017 |
| Sonic Hedgehog/Gli1 signaling pathway regulates cell migration and invasion via induction of epithelial-to-mesenchymal transition in gastric cancer B Ke, XN Wang, N Liu, B Li, XJ Wang, RP Zhang, H Liang Journal of Cancer 11 (13), 3932, 2020 | 36 | 2020 |
| Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence B Li, Q Hu, R Xu, H Ren, E Fei, D Chen, G Wang BMC cell biology 13, 1-10, 2012 | 34 | 2012 |
| The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling C Shen, A Nayak, LR Neitzel, AA Adams, M Silver-Isenstadt, LM Sawyer, ... Nature communications 12 (1), 5263, 2021 | 31 | 2021 |
| Acetylation of mastermind-like 1 by p300 drives the recruitment of NACK to initiate notch-dependent transcription K Jin, W Zhou, X Han, Z Wang, B Li, S Jeffries, W Tao, DJ Robbins, ... Cancer Research 77 (16), 4228-4237, 2017 | 30 | 2017 |
| The protease Omi cleaves the mitogen-activated protein kinase kinase MEK1 to inhibit microglial activation Q Hu, B Li, R Xu, D Chen, C Mu, E Fei, G Wang Science signaling 5 (238), ra61-ra61, 2012 | 29 | 2012 |
| A CK1α activator penetrates the brain and shows efficacy against drug-resistant metastatic medulloblastoma J Rodriguez-Blanco, B Li, J Long, C Shen, F Yang, D Orton, S Collins, ... Clinical cancer research 25 (4), 1379-1388, 2019 | 28 | 2019 |