| Multiple functional neurosteroid binding sites on GABAA receptors ZW Chen, JR Bracamontes, MM Budelier, AL Germann, DJ Shin, ... PLoS Biology 17 (3), e3000157, 2019 | 104 | 2019 |
| Mechanism for selectivity-inactivation coupling in KcsA potassium channels WWL Cheng, JG McCoy, AN Thompson, CG Nichols, CM Nimigean Proceedings of the National Academy of Sciences 108 (13), 5272-5277, 2011 | 102 | 2011 |
| Direct and specific activation of human inward rectifier K+ channels by membrane phosphatidylinositol 4, 5-bisphosphate N D'Avanzo, WWL Cheng, DA Doyle, CG Nichols Journal of biological chemistry 285 (48), 37129-37132, 2010 | 86 | 2010 |
| A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression P Nagele, BJ Palanca, B Gott, F Brown, L Barnes, T Nguyen, W Xiong, ... Science translational medicine 13 (597), eabe1376, 2021 | 80 | 2021 |
| Dual-mode phospholipid regulation of human inward rectifying potassium channels WWL Cheng, N D'Avanzo, DA Doyle, CG Nichols Biophysical journal 100 (3), 620-628, 2011 | 80 | 2011 |
| Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1 MM Budelier, WWL Cheng, L Bergdoll, ZW Chen, JW Janetka, ... Journal of Biological Chemistry 292 (22), 9294-9304, 2017 | 78 | 2017 |
| KirBac1. 1: it's an inward rectifying potassium channel WWL Cheng, D Enkvetchakul, CG Nichols Biophysical Journal 96 (3), 467a, 2009 | 64 | 2009 |
| The role of the cytoplasmic pore in inward rectification of Kir2. 1 channels HT Kurata, WW Cheng, C Arrabit, PA Slesinger, CG Nichols The Journal of general physiology 130 (2), 145-155, 2007 | 55 | 2007 |
| Site-specific effects of neurosteroids on GABAA receptor activation and desensitization Y Sugasawa, WWL Cheng, JR Bracamontes, ZW Chen, L Wang, ... Elife 9, e55331, 2020 | 51 | 2020 |
| Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel A Tong, JT Petroff, FF Hsu, PAM Schmidpeter, CM Nimigean, L Sharp, ... Elife 8, e50766, 2019 | 41 | 2019 |
| Energetics and location of phosphoinositide binding in human Kir2. 1 channels N D'Avanzo, SJ Lee, WWL Cheng, CG Nichols Journal of Biological Chemistry 288 (23), 16726-16737, 2013 | 41 | 2013 |
| Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC WWL Cheng, ZW Chen, JR Bracamontes, MM Budelier, K Krishnan, ... Journal of Biological Chemistry 293 (8), 3013-3027, 2018 | 37 | 2018 |
| Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling WWL Cheng, MM Budelier, Y Sugasawa, L Bergdoll, M Queralt-Martín, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 33 | 2019 |
| Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel MM Budelier, WWL Cheng, ZW Chen, JR Bracamontes, Y Sugasawa, ... Biochimica Et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 33 | 2019 |
| Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains JJ Paynter, I Andres-Enguix, PW Fowler, S Tottey, W Cheng, ... Journal of biological chemistry 285 (52), 40754-40761, 2010 | 30 | 2010 |
| Numerical fluorescence correlation spectroscopy for the analysis of molecular dynamics under nonstandard conditions MJ Culbertson, JTB Williams, WWL Cheng, DA Stults, ER Wiebracht, ... Analytical chemistry 79 (11), 4031-4039, 2007 | 30 | 2007 |
| Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel V Dalal, MJ Arcario, JT Petroff, BK Tan, NM Dietzen, MJ Rau, ... Nature communications 15 (1), 25, 2024 | 29 | 2024 |
| Expression and purification of recombinant human inward rectifier K+ (KCNJ) channels in Saccharomyces cerevisiae N D’Avanzo, WWL Cheng, X Xia, L Dong, P Savitsky, CG Nichols, ... Protein expression and purification 71 (1), 115-121, 2010 | 29 | 2010 |
| Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1 PAM Schmidpeter, JT Petroff, L Khajoueinejad, A Wague, C Frankfater, ... Nature communications 14 (1), 1077, 2023 | 28 | 2023 |
| Click chemistry reagent for identification of sites of covalent ligand incorporation in integral membrane proteins MM Budelier, WWL Cheng, L Bergdoll, ZW Chen, J Abramson, K Krishnan, ... Analytical chemistry 89 (4), 2636-2644, 2017 | 27 | 2017 |
Colin G NicholsWashington UniversityVerified email at wustl.edu
