| Cell-programmed nutrient partitioning in the tumour microenvironment BI Reinfeld, MZ Madden, MM Wolf, A Chytil, JE Bader, AR Patterson, ... Nature 593 (7858), 282-288, 2021 | 769 | 2021 |
| Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ... Cell 175 (7), 1780-1795. e19, 2018 | 606 | 2018 |
| SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination W Daddacha, AE Koyen, AJ Bastien, PSE Head, VR Dhere, GN Nabeta, ... Cell reports 20 (8), 1921-1935, 2017 | 189 | 2017 |
| MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function A Sugiura, G Andrejeva, K Voss, DR Heintzman, X Xu, MZ Madden, X Ye, ... Immunity 55 (1), 65-81. e9, 2022 | 126 | 2022 |
| Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response LS Levine, KJ Hiam-Galvez, DM Marquez, I Tenvooren, MZ Madden, ... Immunity 54 (4), 829-844. e5, 2021 | 110 | 2021 |
| The complex integration of T-cell metabolism and immunotherapy MZ Madden, JC Rathmell Cancer Discovery 11 (7), 1636-1643, 2021 | 103 | 2021 |
| ATRIP deacetylation by SIRT2 drives ATR checkpoint activation by promoting binding to RPA-ssDNA H Zhang, PSE Head, W Daddacha, SH Park, X Li, Y Pan, MZ Madden, ... Cell reports 14 (6), 1435-1447, 2016 | 74 | 2016 |
| CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer LE Colbert, AV Petrova, SB Fisher, BG Pantazides, MZ Madden, ... Cancer research 74 (10), 2677-2687, 2014 | 73 | 2014 |
| A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response SC Smith, AV Petrova, MZ Madden, H Wang, Y Pan, MD Warren, ... Nucleic acids research 42 (18), 11517-11527, 2014 | 51 | 2014 |
| STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy L Wang-Bishop, BR Kimmel, VM Ngwa, MZ Madden, JJ Baljon, ... Science immunology 8 (83), eadd1153, 2023 | 46 | 2023 |
| EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair AE Koyen, MZ Madden, D Park, EV Minten, P Kapoor-Vazirani, E Werner, ... Oncogene 39 (25), 4798-4813, 2020 | 42 | 2020 |
| Macrophages promote aortic valve cell calcification and alter STAT3 splicing MA Raddatz, T Huffstater, MR Bersi, BI Reinfeld, MZ Madden, SE Booton, ... Arteriosclerosis, thrombosis, and vascular biology 40 (6), e153-e165, 2020 | 40 | 2020 |
| Obesity induces PD-1 on macrophages to suppress anti-tumour immunity JE Bader, MM Wolf, GL Lupica-Tondo, MZ Madden, BI Reinfeld, EN Arner, ... Nature, 1-8, 2024 | 33 | 2024 |
| Leptin augments antitumor immunity in obesity by repolarizing tumor-associated macrophages SO Dudzinski, JE Bader, KE Beckermann, KL Young, R Hongo, ... The Journal of Immunology 207 (12), 3122-3130, 2021 | 30 | 2021 |
| Targeting in vivo metabolic vulnerabilities of Th2 and Th17 cells reduces airway inflammation DCC Healey, JY Cephus, SM Barone, NU Chowdhury, DO Dahunsi, ... The Journal of Immunology 206 (6), 1127-1139, 2021 | 24 | 2021 |
| Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer EB Glass, AA Hoover, KK Bullock, MZ Madden, BI Reinfeld, W Harris, ... BMC cancer 22 (1), 497, 2022 | 23 | 2022 |
| Differential effects of glutamine inhibition strategies on antitumor CD8 T cells MZ Madden, X Ye, C Chi, EL Fisher, MM Wolf, GA Needle, JE Bader, ... The Journal of Immunology 211 (4), 563-575, 2023 | 13 | 2023 |
| VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis MM Wolf, MZ Madden, EN Arner, JE Bader, X Ye, L Vlach, ML Tigue, ... Journal of Clinical Investigation 134 (8), e173934, 2024 | 5 | 2024 |
| Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic–Epigenetic Cross-Talk DL Greenwood, HE Ramsey, PTT Nguyen, AR Patterson, K Voss, ... ImmunoHorizons 6 (12), 837-850, 2022 | 4 | 2022 |
| Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation NU Chowdhury, JY Cephus, EH Pilier, MM Wolf, MZ Madden, SN Kuehnle, ... The Journal of Clinical Investigation 134 (23), 2024 | 1 | 2024 |
Jeffrey C RathmellCornelius Vanderbilt Professor of Immunobiology, Vanderbilt Center for ImmunobiologyVerified email at vanderbilt.edu