Adolescent Δ9-tetrahydrocannabinol exposure and astrocyte-specific genetic vulnerability converge on nuclear factor-κB–cyclooxygenase-2 signaling to impair memory in adulthood Y Jouroukhin, X Zhu, AV Shevelkin, Y Hasegawa, B Abazyan, A Saito, ... Biological psychiatry 85 (11), 891-903, 2019 | 51 | 2019 |
Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice TC Tzeng, Y Hasegawa, R Iguchi, A Cheung, DR Caffrey, EJ Thatcher, ... Proceedings of the National Academy of Sciences 115 (36), 9002-9007, 2018 | 48 | 2018 |
Dectin-1 signaling on colonic γδ T cells promotes psychosocial stress responses X Zhu, S Sakamoto, C Ishii, MD Smith, K Ito, M Obayashi, L Unger, ... Nature immunology 24 (4), 625-636, 2023 | 46 | 2023 |
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress X Zhu, MT Nedelcovych, AG Thomas, Y Hasegawa, A Moreno-Megui, ... Neuropsychopharmacology 44 (4), 683-694, 2019 | 45 | 2019 |
In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene CJ Peter, A Saito, Y Hasegawa, Y Tanaka, M Nagpal, G Perez, E Alway, ... Nature communications 10 (1), 4112, 2019 | 44 | 2019 |
Inflamed brain: targeting immune changes and inflammation for treatment of depression S Sakamoto, X Zhu, Y Hasegawa, S Karma, M Obayashi, E Alway, ... Psychiatry and clinical neurosciences 75 (10), 304-311, 2021 | 35 | 2021 |
Activity-induced regulation of synaptic strength through the chromatin reader L3mbtl1 W Mao, AC Salzberg, M Uchigashima, Y Hasegawa, H Hock, ... Cell reports 23 (11), 3209-3222, 2018 | 35 | 2018 |
Olfactory impairment in psychiatric disorders: Does nasal inflammation impact disease psychophysiology? Y Hasegawa, M Ma, A Sawa, AP Lane, A Kamiya Translational psychiatry 12 (1), 314, 2022 | 31 | 2022 |
Astrocyte DISC1 contributes to cognitive function in a brain region-dependent manner AV Shevelkin, CE Terrillion, Y Hasegawa, OA Mychko, Y Jouroukhin, ... Human molecular genetics 29 (17), 2936-2950, 2020 | 20 | 2020 |
NV-5138 as a fast-acting antidepressant via direct activation of mTORC1 signaling Y Hasegawa, X Zhu, A Kamiya The Journal of clinical investigation 129 (6), 2207-2209, 2019 | 19 | 2019 |
Causal impact of local inflammation in the nasal cavity on higher brain function and cognition Y Hasegawa, H Namkung, A Smith, S Sakamoto, X Zhu, K Ishizuka, ... Neuroscience research 172, 110-115, 2021 | 16 | 2021 |
Luciferase shRNA presents off-target effects on voltage-gated ion channels in mouse hippocampal pyramidal neurons Y Hasegawa, W Mao, S Saha, G Gunner, J Kolpakova, GE Martin, K Futai eneuro 4 (5), 2017 | 13 | 2017 |
Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11. 2 duplication Y Hasegawa, J Kim, G Ursini, Y Jouroukhin, X Zhu, Y Miyahara, F Xiong, ... Nature communications 14 (1), 6559, 2023 | 6 | 2023 |
Kano X Zhu, S Sakamoto, C Ishii, MD Smith, K Ito, M Obayashi, L Unger, ... S. ichi, Fukuda, S., Sanada, K., Calabresi, PA, & Kamiya, A, 2023 | 6 | 2023 |
Immune-related molecular changes in the olfactory epithelium, structural alteration in the olfactory bulb, and psychosis. K Yang, Y Hasegawa, J Hua, M Dower, S Etyemez, N Prasad, L Duvall, ... Biorxiv: the Preprint Server for Biology, 2022 | 5* | 2022 |
Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice BJ Bell, KR Hollinger, P Deme, S Sakamoto, Y Hasegawa, D Volsky, ... Brain, Behavior, & Immunity-Health 23, 100478, 2022 | 5 | 2022 |
Cannabis effects on the adolescent brain K Murlanova, Y Hasegawa, A Kamiya, MV Pletnikov Cannabis and the developing brain, 283-330, 2022 | 4 | 2022 |
Correction: JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat … X Zhu, MT Nedelcovych, AG Thomas, Y Hasegawa, A Moreno-Megui, ... Neuropsychopharmacology 44 (6), 1178-1178, 2019 | 2 | 2019 |
Adolescent Δ9-THC exposure and astrocyte-specific genetic vulnerability converge on NF-κB-COX-2 signaling to impair memory in adulthood Y Jouroukhin, X Zhu, AV Shevelkin, Y Hasegawa, B Abazyan, A Saito, ... Biological psychiatry 85 (11), 891, 2018 | 2 | 2018 |
Synergistic Impact of Microglia-Mediated Adverse Effect of Adolescent THC Exposure and 16p11. 2 Duplication on Prefrontal Cortex Maturation and Social Memory Y Hasegawa, J Kim, G Ursini, Y Jouroukhin, X Zhu, Y Miyahara, F Xiong, ... NEUROPSYCHOPHARMACOLOGY 48, 365-365, 2023 | | 2023 |