| CD19+ CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients PA Blair, LY Noreña, F Flores-Borja, DJ Rawlings, DA Isenberg, ... immunity 32 (1), 129-140, 2010 | 1833 | 2010 |
| Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy MR Ehrenstein, JG Evans, A Singh, S Moore, G Warnes, DA Isenberg, ... The Journal of experimental medicine 200 (3), 277-285, 2004 | 1708 | 2004 |
| CD19+ CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation F Flores-Borja, A Bosma, D Ng, V Reddy, MR Ehrenstein, DA Isenberg, ... Science translational medicine 5 (173), 173ra23-173ra23, 2013 | 798 | 2013 |
| An open study of B lymphocyte depletion in systemic lupus erythematosus MJ Leandro, JC Edwards, G Cambridge, MR Ehrenstein, DA Isenberg Arthritis & Rheumatism 46 (10), 2673-2677, 2002 | 777 | 2002 |
| The importance of natural IgM: scavenger, protector and regulator MR Ehrenstein, CA Notley Nature Reviews Immunology 10 (11), 778-786, 2010 | 766 | 2010 |
| Novel suppressive function of transitional 2 B cells in experimental arthritis JG Evans, KA Chavez-Rueda, A Eddaoudi, A Meyer-Bahlburg, ... The Journal of Immunology 178 (12), 7868-7878, 2007 | 704 | 2007 |
| Reconstitution of peripheral blood B cells after depletion with rituximab in patients with rheumatoid arthritis MJ Leandro, G Cambridge, MR Ehrenstein, JCW Edwards Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 647 | 2006 |
| Anti–TNF-α therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-β S Nadkarni, C Mauri, MR Ehrenstein The Journal of experimental medicine 204 (1), 33-39, 2007 | 614 | 2007 |
| Serologic changes following B lymphocyte depletion therapy for rheumatoid arthritis G Cambridge, MJ Leandro, JCW Edwards, MR Ehrenstein, M Salden, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 603 | 2003 |
| Mice lacking endogenous IL-10–producing regulatory B cells develop exacerbated disease and present with an increased frequency of Th1/Th17 but a decrease in regulatory T cells NA Carter, R Vasconcellos, EC Rosser, C Tulone, A Muñoz-Suano, ... The Journal of Immunology 186 (10), 5569-5579, 2011 | 571 | 2011 |
| The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice JS Brown, T Hussell, SM Gilliland, DW Holden, JC Paton, MR Ehrenstein, ... Proceedings of the National Academy of Sciences 99 (26), 16969-16974, 2002 | 509 | 2002 |
| B-cell depletion in the treatment of patients with systemic lupus erythematosus: a longitudinal analysis of 24 patients MJ Leandro, G Cambridge, JC Edwards, MR Ehrenstein, DA Isenberg Rheumatology 44 (12), 1542-1545, 2005 | 469 | 2005 |
| Human FoxP3+ regulatory T cells in systemic autoimmune diseases M Miyara, G Gorochov, M Ehrenstein, L Musset, S Sakaguchi, Z Amoura Autoimmunity reviews 10 (12), 744-755, 2011 | 424 | 2011 |
| Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting C Rada, MR Ehrenstein, MS Neuberger, C Milstein Immunity 9 (1), 135-141, 1998 | 420 | 1998 |
| The ‘short’history of regulatory B cells C Mauri, MR Ehrenstein Trends in immunology 29 (1), 34-40, 2008 | 408 | 2008 |
| Fifty years of anti-ds DNA antibodies: are we approaching journey's end? DA Isenberg, JJ Manson, MR Ehrenstein, A Rahman Oxford University Press 46 (7), 1052-1056, 2007 | 380 | 2007 |
| International consensus outcome measures for patients with idiopathic inflammatory myopathies. Development and initial validation of myositis activity and damage indices in … DA Isenberg, E Allen, V Farewell, MR Ehrenstein, MG Hanna, ... Rheumatology 43 (1), 49-54, 2004 | 380 | 2004 |
| Selective targeting of B cells with agonistic anti-CD40 is an efficacious strategy for the generation of induced regulatory T2-like B cells and for the suppression of lupus in … PA Blair, KA Chavez-Rueda, JG Evans, MJ Shlomchik, A Eddaoudi, ... The Journal of Immunology 182 (6), 3492-3502, 2009 | 377 | 2009 |
| Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis F Flores-Borja, EC Jury, C Mauri, MR Ehrenstein Proceedings of the National Academy of Sciences 105 (49), 19396-19401, 2008 | 367 | 2008 |
| A retrospective seven‐year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at university college london hospital: the first fifty patients TYT Lu, KP Ng, G Cambridge, MJ Leandro, JCW Edwards, M Ehrenstein, ... Arthritis Care & Research: Official Journal of the American College of …, 2009 | 330 | 2009 |