| Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018 | 1383 | 2018 |
| A benchmark for comparison of cell tracking algorithms M Maška, V Ulman, D Svoboda, P Matula, P Matula, C Ederra, A Urbiola, ... Bioinformatics 30 (11), 1609-1617, 2014 | 506 | 2014 |
| Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ... The Lancet 396 (10246), e6-e7, 2020 | 253 | 2020 |
| DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer N Kanu, MA Cerone, G Goh, LP Zalmas, J Bartkova, M Dietzen, ... Genome biology 17, 1-15, 2016 | 184 | 2016 |
| Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution S Venkatesan, R Rosenthal, N Kanu, N McGranahan, J Bartek, ... Annals of Oncology 29 (3), 563-572, 2018 | 168 | 2018 |
| Tumor evolutionary principles: how intratumor heterogeneity influences cancer treatment and outcome S Venkatesan, C Swanton American Society of Clinical Oncology Educational Book 36, e141-e149, 2016 | 121 | 2016 |
| Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution S Venkatesan, M Angelova, C Puttick, H Zhai, DR Caswell, WT Lu, ... Cancer discovery 11 (10), 2456-2473, 2021 | 106 | 2021 |
| Treatment-induced mutagenesis and selective pressures sculpt cancer evolution S Venkatesan, C Swanton, BS Taylor, JF Costello Cold Spring Harbor perspectives in medicine 7 (8), a026617, 2017 | 91 | 2017 |
| DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells LMEB Pont, K Naipal, JJ Kloezeman, S Venkatesan, M van den Bent, ... Cancer letters 356 (2), 525-535, 2015 | 52 | 2015 |
| The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells LMEB Pont, JKH Spoor, S Venkatesan, S Swagemakers, JJ Kloezeman, ... Genes & Cancer 5 (11-12), 445, 2014 | 46 | 2014 |
| Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma S Venkatesan, MLM Lamfers, CMF Dirven, S Leenstra CNS oncology 5 (2), 77-90, 2016 | 38 | 2016 |
| The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance DR Caswell, P Gui, MK Mayekar, EK Law, O Pich, C Bailey, J Boumelha, ... Nature Genetics 56 (1), 60-73, 2024 | 37 | 2024 |
| Constraints in cancer evolution S Venkatesan, NJ Birkbak, C Swanton Biochemical Society Transactions 45 (1), 1-13, 2017 | 30 | 2017 |
| Targeted cancer therapy induces APOBEC fueling the evolution of drug resistance M Mayekar, D Caswell, N Vokes, EK Law, W Wu, W Hill, E Gronroos, ... Cancer Research 82 (12_Supplement), 2197-2197, 2022 | 19 | 2022 |
| The basal interstitial nucleus (BIN) of the cerebellum provides diffuse ascending inhibitory input to the floccular granule cell layer D Jaarsma, FGC Blot, B Wu, S Venkatesan, J Voogd, D Meijer, ... Journal of Comparative Neurology 526 (14), 2231-2256, 2018 | 18 | 2018 |
| Overview of the patent expiry of (non-) tyrosine kinase inhibitors approved for clinical use in the EU and the US S Venkatesan, M Lamfers, S Leenstra, AG Vulto GaBI Journal 6 (2), 89-96, 2017 | 13 | 2017 |
| Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling S Hobor, M Al Bakir, CT Hiley, M Skrzypski, AM Frankell, B Bakker, ... Nature Communications 15 (1), 4871, 2024 | 11 | 2024 |
| Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse M Chen, S Mainardi, C Lieftink, A Velds, I de Rink, C Yang, HJ Kuiken, ... Cell Reports Medicine 5 (3), 2024 | 11 | 2024 |
| Evolutionary dynamics in pre-invasive neoplasia C Abbosh, S Venkatesan, SM Janes, RC Fitzgerald, C Swanton Current opinion in systems biology 2, 1-8, 2017 | 11 | 2017 |
| TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition … S Venkatesan, M Hoogstraat, E Caljouw, T Pierson, JKH Spoor, ... Oncotarget 7 (36), 58435, 2016 | 10 | 2016 |