| Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses JB Mitchem, DJ Brennan, BL Knolhoff, BA Belt, Y Zhu, DE Sanford, ... Cancer research 73 (3), 1128-1141, 2013 | 1053 | 2013 |
| Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis DE Sanford, BA Belt, RZ Panni, A Mayer, AD Deshpande, D Carpenter, ... Clinical cancer research 19 (13), 3404-3415, 2013 | 661 | 2013 |
| Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth MR Porembka, JB Mitchem, BA Belt, CS Hsieh, HM Lee, J Herndon, ... Cancer Immunology, Immunotherapy 61, 1373-1385, 2012 | 318 | 2012 |
| Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer RZ Panni, DE Sanford, BA Belt, JB Mitchem, LA Worley, BD Goetz, ... Cancer Immunology, Immunotherapy 63, 513-528, 2014 | 223 | 2014 |
| Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure JB Mitchem, N Hamilton, F Gao, WG Hawkins, DC Linehan, SM Strasberg Journal of the American College of Surgeons 214 (1), 46-52, 2012 | 177 | 2012 |
| Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer JL Gnerlich, JB Mitchem, JS Weir, NV Sankpal, H Kashiwagi, BA Belt, ... The Journal of Immunology 185 (7), 4063-4071, 2010 | 171 | 2010 |
| Myeloid-derived suppressor cells: general characteristics and relevance to clinical management of pancreatic cancer P Goedegebuure, J B Mitchem, M R Porembka, M CB Tan, B A Belt, ... Current cancer drug targets 11 (6), 734-751, 2011 | 127 | 2011 |
| A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma A Wang-Gillam, S Plambeck-Suess, P Goedegebuure, PO Simon, ... Investigational new drugs 31, 707-713, 2013 | 114 | 2013 |
| The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine JR Hornick, J Xu, S Vangveravong, Z Tu, JB Mitchem, D Spitzer, ... Molecular cancer 9, 1-11, 2010 | 99 | 2010 |
| Tumor-cell–macrophage fusion cells as liquid biomarkers and tumor enhancers in cancer Y Manjunath, D Porciani, JB Mitchem, KN Suvilesh, DM Avella, ET Kimchi, ... International journal of molecular sciences 21 (5), 1872, 2020 | 81 | 2020 |
| Impact of neoadjuvant chemotherapy on rate of tissue expander/implant loss and progression to successful breast reconstruction following mastectomy J Mitchem, D Herrmann, JA Margenthaler, RL Aft The American journal of surgery 196 (4), 519-522, 2008 | 78 | 2008 |
| A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater: management and outcomes JR Hornick, FM Johnston, PO Simon, M Younkin, M Chamberlin, ... Surgery 150 (2), 169-176, 2011 | 64 | 2011 |
| Circulating giant tumor-macrophage fusion cells are independent prognosticators in patients with NSCLC Y Manjunath, JB Mitchem, KN Suvilesh, DM Avella, ET Kimchi, ... Journal of Thoracic Oncology 15 (9), 1460-1471, 2020 | 58 | 2020 |
| FOLFOX chemotherapy ameliorates CD8 T lymphocyte exhaustion and enhances checkpoint blockade efficacy in colorectal cancer Y Guan, SG Kraus, MJ Quaney, MA Daniels, JB Mitchem, E Teixeiro Frontiers in oncology 10, 586, 2020 | 55 | 2020 |
| Pattern of lymph node involvement and prognosis in pancreatic adenocarcinoma: direct lymph node invasion has similar survival to node-negative disease RK Pai, AH Beck, J Mitchem, DC Linehan, DT Chang, JA Norton, RK Pai The American journal of surgical pathology 35 (2), 228-234, 2011 | 55 | 2011 |
| A study of zoledronic acid as neo-adjuvant, perioperative therapy in patients with resectable pancreatic ductal adenocarcinoma DE Sanford, MR Porembka, RZ Panni, JB Mitchem, BA Belt, ... Journal of cancer therapy 4 (3), 797, 2013 | 34 | 2013 |
| Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses KN Suvilesh, YI Nussbaum, V Radhakrishnan, Y Manjunath, DM Avella, ... Molecular Cancer 21 (1), 73, 2022 | 32 | 2022 |
| Explainable artificial intelligence in high-throughput drug repositioning for subgroup stratifications with interventionable potential Z Al-Taie, D Liu, JB Mitchem, C Papageorgiou, JT Kaifi, WC Warren, ... Journal of Biomedical Informatics 118, 103792, 2021 | 25 | 2021 |
| Evaluation of a tumor-targeting, near-infrared fluorescent peptide for early detection and endoscopic resection of polyps in a rat model of colorectal cancer JE Jones, SB Busi, JB Mitchem, JM Amos-Landgraf, MR Lewis Molecular imaging 17, 1536012118790065, 2018 | 23 | 2018 |
| Battle over CCL2 for control of the metastatic niche: neutrophils versus monocytes JB Mitchem, DG DeNardo Breast Cancer Research 14, 1-3, 2012 | 22 | 2012 |
David C. LinehanProfessor of Surgery, University of RochesterVerified email at urmc.rochester.edu
