| Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice P Liu, SQ Liang, C Zheng, E Mintzer, YG Zhao, K Ponnienselvan, A Mir, ... Nature communications 12 (1), 2121, 2021 | 242 | 2021 |
| Combinatorial design of nanoparticles for pulmonary mRNA delivery and genome editing B Li, RS Manan, SQ Liang, A Gordon, A Jiang, A Varley, G Gao, R Langer, ... Nature biotechnology 41 (10), 1410-1415, 2023 | 140 | 2023 |
| New Horizons in KRAS-Mutant Lung Cancer: Dawn After Darkness H Yang, SQ Liang, RA Schmid, RW Peng Frontiers in oncology 9, 953, 2019 | 140 | 2019 |
| A split prime editor with untethered reverse transcriptase and circular RNA template B Liu, X Dong, H Cheng, C Zheng, Z Chen, TC Rodríguez, SQ Liang, ... Nature Biotechnology 40 (9), 1388-1393, 2022 | 125 | 2022 |
| Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins J Lee, H Mou, R Ibraheim, SQ Liang, P Liu, W Xue, EJ Sontheimer Rna 25 (11), 1421-1431, 2019 | 99 | 2019 |
| Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer SQ Liang, TM Marti, P Dorn, L Froment, SRR Hall, S Berezowska, ... Cell death & disease 6 (7), e1824-e1824, 2015 | 89 | 2015 |
| A flexible split prime editor using truncated reverse transcriptase improves dual-AAV delivery in mouse liver C Zheng, SQ Liang, B Liu, P Liu, SY Kwan, SA Wolfe, W Xue Molecular Therapy 30 (3), 1343-1351, 2022 | 87 | 2022 |
| HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer H Yang, SQ Liang, D Xu, Z Yang, TM Marti, Y Gao, GJ Kocher, H Zhao, ... Oncogenesis 8 (9), 45, 2019 | 54 | 2019 |
| mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer SQ Liang, ED Bührer, S Berezowska, TM Marti, D Xu, L Froment, H Yang, ... Oncogene 38 (5), 622-636, 2019 | 52 | 2019 |
| Genome-wide detection of CRISPR editing in vivo using GUIDE-tag SQ Liang, P Liu, JL Smith, E Mintzer, S Maitland, X Dong, Q Yang, J Lee, ... Nature communications 13 (1), 437, 2022 | 42 | 2022 |
| Endoplasmic reticulum stress signaling as a therapeutic target in malignant pleural mesothelioma D Xu, H Yang, Z Yang, S Berezowska, Y Gao, SQ Liang, TM Marti, ... Cancers 11 (10), 1502, 2019 | 36 | 2019 |
| CRISPR screening identifies WEE1 as a combination target for standard chemotherapy in malignant pleural mesothelioma D Xu, SQ Liang, H Yang, R Bruggmann, S Berezowska, Z Yang, TM Marti, ... Molecular cancer therapeutics 19 (2), 661-672, 2020 | 35 | 2020 |
| Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma D Xu, SQ Liang, H Yang, U Lüthi, C Riether, S Berezowska, TM Marti, ... British journal of cancer 119 (1), 65-75, 2018 | 35 | 2018 |
| Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag SQ Liang, P Liu, K Ponnienselvan, S Suresh, Z Chen, C Kramme, ... Nature Methods 20 (6), 898-907, 2023 | 34 | 2023 |
| AAV5 delivery of CRISPR-Cas9 supports effective genome editing in mouse lung airway SQ Liang, CJ Walkey, AE Martinez, Q Su, ME Dickinson, D Wang, ... Molecular Therapy 30 (1), 238-243, 2022 | 34 | 2022 |
| Immune response of turbot (Scophthalmus maximus L.) to a broad spectrum vaccine candidate, recombinant glyceraldehyde-3-phosphate dehydrogenase of Edwardsiella tarda S Liang, H Wu, B Liu, J Xiao, Q Wang, Y Zhang Veterinary immunology and immunopathology 150 (3-4), 198-205, 2012 | 34 | 2012 |
| Secreted glyceraldehyde‐3‐phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture X Li, H Wu, M Zhang, S Liang, J Xiao, Q Wang, Q Liu, Y Zhang Letters in applied microbiology 54 (1), 1-9, 2012 | 32 | 2012 |
| Analysis of unexpected small cell lung cancer following surgery as the primary treatment H Yang, J Xu, F Yao, S Liang, H Zhao Journal of cancer research and clinical oncology 144, 2441-2447, 2018 | 22 | 2018 |
| YAP1 withdrawal in hepatoblastoma drives therapeutic differentiation of tumor cells to functional hepatocyte‐like cells JL Smith, TC Rodríguez, H Mou, SY Kwan, H Pratt, XO Zhang, Y Cao, ... Hepatology 73 (3), 1011-1027, 2021 | 20 | 2021 |
| CRISPR-mediated kinome editing prioritizes a synergistic combination therapy for FGFR1-amplified lung cancer Z Yang, SQ Liang, H Yang, D Xu, R Bruggmann, Y Gao, H Deng, ... Cancer research 81 (11), 3121-3133, 2021 | 18 | 2021 |
Ren-Wang PengUniversity Hospital Bern, University of BernVerified email at insel.ch
