Coactivator condensation at super-enhancers links phase separation and gene control BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... Science 361 (6400), eaar3958, 2018 | 2167 | 2018 |
Transcription factors activate genes through the phase-separation capacity of their activation domains A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ... Cell 175 (7), 1842-1855. e16, 2018 | 1574 | 2018 |
Partitioning of cancer therapeutics in nuclear condensates IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Science 368 (6497), 1386-1392, 2020 | 394 | 2020 |
Enhancer features that drive formation of transcriptional condensates K Shrinivas, BR Sabari, EL Coffey, IA Klein, A Boija, AV Zamudio, ... Molecular cell 75 (3), 549-561. e7, 2019 | 381 | 2019 |
Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular cell 76 (5), 753-766. e6, 2019 | 242 | 2019 |
MeCP2 links heterochromatin condensates and neurodevelopmental disease CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ... Nature 586 (7829), 440-444, 2020 | 179 | 2020 |
Antisense lncRNA transcription mediates DNA demethylation to drive stochastic protocadherin α promoter choice D Canzio, CL Nwakeze, A Horta, SM Rajkumar, EL Coffey, EE Duffy, ... Cell 177 (3), 639-653. e15, 2019 | 149 | 2019 |
Widespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination MG Hasham, NM Donghia, E Coffey, J Maynard, KJ Snow, J Ames, ... Nature immunology 11 (9), 820-826, 2010 | 120 | 2010 |
Coactivator condensation at super-enhancers links phase separation and gene control. Science BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... | 12 | 2018 |
Methods and assays for modulating gene transcription by modulating condensates RA Young, PA Sharp, AK Chakraborty, A Dall'Agnese, K Shrinivas, ... US Patent App. 17/040,967, 2022 | 3 | 2022 |
Biomolecular Condensates in Transcriptional Regulation EL Coffey Massachusetts Institute of Technology, 2021 | 2 | 2021 |
Antisense lncRNA transcription drives stochastic Protocadherin α promoter choice D Canzio, CL Nwakeze, A Horta, SM Rajkumar, EL Coffey, EE Duffy, ... bioRxiv, 360206, 2018 | 2 | 2018 |
Abstract GS3-10: Partitioning of cancer therapeutics in nuclear condensates I Klein, A Boija, L Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Cancer Research 81 (4_Supplement), GS3-10-GS3-10, 2021 | | 2021 |
Risks to mitigation potential of forests AM Sugden Science 368 (6497), 1324-1326, 2020 | | 2020 |
Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes A Zamudio Montes de Oca, A Dall’Agnese, JE Henninger, JC Manteiga, ... Elsevier BV, 2019 | | 2019 |
Phase separation in transcriptional control of super-enhancer regulated genes. AV Zamudio, BR Sabari, A Dall'Agnese, A Boija, IA Klein, EL Coffey, ... MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |
7q36 and genome stability: investigating Xrcc2. E Coffey | | 2009 |
Phase Separation Concentrates Transcription Proteins at Superenhancers BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas | | |