Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms L Arranz, A Sánchez-Aguilera, D Martín-Pérez, J Isern, X Langa, ... Nature 512 (7512), 78-81, 2014 | 496 | 2014 |
The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function J Isern, A García-García, AM Martín, L Arranz, D Martín-Pérez, C Torroja, ... Elife 3, e03696, 2014 | 312 | 2014 |
The embryonic origins of erythropoiesis in mammals MH Baron, J Isern, ST Fraser Blood, The Journal of the American Society of Hematology 119 (21), 4828-4837, 2012 | 246 | 2012 |
Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression ST Fraser, J Isern, MH Baron Blood 109 (1), 343-352, 2007 | 186 | 2007 |
Self-renewing human bone marrow mesenspheres promote hematopoietic stem cell expansion J Isern, B Martín-Antonio, R Ghazanfari, AM Martín, JA Lopez, R Del Toro, ... Cell reports 3 (5), 1714-1724, 2013 | 170 | 2013 |
Cell transcriptomic atlas of the non-human primate Macaca fascicularis L Han, X Wei, C Liu, G Volpe, Z Zhuang, X Zou, Z Wang, T Pan, Y Yuan, ... Nature 604 (7907), 723-731, 2022 | 139 | 2022 |
Low/negative expression of PDGFR-α identifies the candidate primary mesenchymal stromal cells in adult human bone marrow H Li, R Ghazanfari, D Zacharaki, N Ditzel, J Isern, M Ekblom, ... Stem cell reports 3 (6), 965-974, 2014 | 130 | 2014 |
Estrogen signaling selectively induces apoptosis of hematopoietic progenitors and myeloid neoplasms without harming steady-state hematopoiesis A Sánchez-Aguilera, L Arranz, D Martín-Pérez, A García-García, ... Cell stem cell 15 (6), 791-804, 2014 | 126 | 2014 |
Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy X Hong, J Isern, S Campanario, E Perdiguero, I Ramírez-Pardo, ... Cell Stem Cell 29 (9), 1298-1314. e10, 2022 | 122 | 2022 |
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality S Alvarez, M Díaz, J Flach, S Rodriguez-Acebes, AJ López-Contreras, ... Nature communications 6 (1), 8548, 2015 | 118 | 2015 |
The fetal liver is a niche for maturation of primitive erythroid cells J Isern, ST Fraser, Z He, MH Baron Proceedings of the National Academy of Sciences 105 (18), 6662-6667, 2008 | 118 | 2008 |
Clonal analysis identifies hemogenic endothelium as the source of the blood-endothelial common lineage in the mouse embryo L Padrón-Barthe, S Temiño, C Villa del Campo, L Carramolino, J Isern, ... Blood, The Journal of the American Society of Hematology 124 (16), 2523-2532, 2014 | 102 | 2014 |
Role of fucosyltransferases in the association between apomucin and Lewis antigen expression in normal and malignant gastric epithelium A Lopez-Ferrer, C De Bolos, C Barranco, M Garrido, J Isern, I Carlstedt, ... Gut 47 (3), 349-356, 2000 | 99 | 2000 |
Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes A García-García, C Korn, M García-Fernández, O Domingues, J Villadiego, ... Blood, The Journal of the American Society of Hematology 133 (3), 224-236, 2019 | 94 | 2019 |
Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo J Isern, Z He, ST Fraser, S Nowotschin, A Ferrer-Vaquer, R Moore, ... Blood, The Journal of the American Society of Hematology 117 (18), 4924-4934, 2011 | 89 | 2011 |
BMP4 signaling directs primitive endoderm-derived XEN cells to an extraembryonic visceral endoderm identity J Artus, P Douvaras, A Piliszek, J Isern, MH Baron, AK Hadjantonakis Developmental biology 361 (2), 245-262, 2012 | 85 | 2012 |
Tg(Afp‐GFP) expression marks primitive and definitive endoderm lineages during mouse development GS Kwon, ST Fraser, GS Eakin, M Mangano, J Isern, KE Sahr, ... Developmental dynamics: an official publication of the American Association …, 2006 | 85 | 2006 |
Stem cell interactions in a bone marrow niche J Isern, S Méndez-Ferrer Current osteoporosis reports 9, 210-218, 2011 | 79 | 2011 |
Translational control by DHX36 binding to 5′ UTR G-quadruplex is essential for muscle stem-cell regenerative functions X Chen, J Yuan, G Xue, S Campanario, D Wang, W Wang, X Mou, ... Nature Communications 12 (1), 5043, 2021 | 57 | 2021 |
Dose-dependent regulation of primitive erythroid maturation and identity by the transcription factor Eklf J Isern, ST Fraser, Z He, H Zhang, MH Baron Blood, The Journal of the American Society of Hematology 116 (19), 3972-3980, 2010 | 45 | 2010 |