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Michael DeRan
Michael DeRan
Broad Institute
Verified email at broadinstitute.org
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Cited by
Year
Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein
M DeRan, J Yang, CH Shen, EC Peters, J Fitamant, P Chan, M Hsieh, ...
Cell reports 9 (2), 495-503, 2014
3362014
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP
E Miller, J Yang, M DeRan, C Wu, AI Su, GMC Bonamy, J Liu, EC Peters, ...
Chemistry & biology 19 (8), 955-962, 2012
3052012
Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway
PY Chan, X Han, B Zheng, M DeRan, J Yu, GK Jarugumilli, H Deng, ...
Nature chemical biology 12 (4), 282-289, 2016
2662016
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis
G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ...
Nature 561 (7721), 63-69, 2018
2022018
Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A
M Pulvino, Y Liang, D Oleksyn, M DeRan, E Van Pelt, J Shapiro, I Sanz, ...
Blood, The Journal of the American Society of Hematology 120 (8), 1668-1677, 2012
1942012
Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors
L He, JH Jhong, Q Chen, KY Huang, K Strittmatter, J Kreuzer, M DeRan, ...
Cell reports 37 (5), 2021
1792021
Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms
V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ...
Cell 170 (1), 199-212. e20, 2017
1722017
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma
EY Chen, MT DeRan, MS Ignatius, KB Grandinetti, R Clagg, KM McCarthy, ...
Proceedings of the National Academy of Sciences 111 (14), 5349-5354, 2014
1522014
Lats1/2 sustain intestinal stem cells and Wnt activation through TEAD-dependent and independent transcription
Q Li, Y Sun, GK Jarugumilli, S Liu, K Dang, JL Cotton, J Xiol, PY Chan, ...
Cell stem cell 26 (5), 675-692. e8, 2020
1502020
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity
B Chen, B Zheng, M DeRan, GK Jarugumilli, J Fu, YS Brooks, X Wu
Nature chemical biology 12 (9), 686-693, 2016
1102016
2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases
B Zheng, M DeRan, X Li, X Liao, M Fukata, X Wu
Journal of the American Chemical Society 135 (19), 7082-7085, 2013
1062013
Transcriptional Activation of Histone Genes Requires NPAT-Dependent Recruitment of TRRAP-Tip60 Complex to Histone Promoters during the G1/S Phase …
M DeRan, M Pulvino, E Greene, C Su, J Zhao
Molecular and cellular biology 28 (1), 435-447, 2008
642008
YAP-dependent proliferation by a small molecule targeting annexin A2
SZ Shalhout, PY Yang, EM Grzelak, K Nutsch, S Shao, C Zambaldo, ...
Nature Chemical Biology 17 (7), 767-775, 2021
432021
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic
AD Westerling-Bui, EM Fast, TW Soare, S Venkatachalan, M DeRan, ...
Science Advances 8 (27), eabj5633, 2022
182022
Chemical Probe to Identify the Cellular Targets of the Reactive Lipid Metabolite 2-trans-Hexadecenal
GK Jarugumilli, JR Choi, PY Chan, M Yu, Y Sun, B Chen, J Niu, M DeRan, ...
ACS chemical biology 13 (5), 1130-1136, 2018
172018
A translational kidney organoid system bolsters human relevance of clinical development candidate
A Westerling-Bui, TW Soare, S Venkatachalan, M DeRan, EM Fast, ...
bioRxiv, 2019.12. 30.891440, 2019
42019
Assessing G1-to-S-Phase Progression After Genotoxic Stress
M DeRan, M Pulvino, J Zhao
Cell Cycle Checkpoints: Methods and Protocols, 221-230, 2011
42011
When small molecules are like real estate: it’s all about location, location, location
M DeRan, BK Wagner
Cell chemical biology 25 (10), 1169-1170, 2018
22018
Colocalization of ovarian cancer-associated biomarkers in tumors, cancer cells and extracellular vesicles
AD Couvillon, ES Winn-Deen, S Thornton, S Liu, M DeRan, M Pacula, ...
Cancer Research 84 (6_Supplement), 1066-1066, 2024
12024
SO038 A TRANSLATIONAL KIDNEY ORGANOID SYSTEM BOLSTERS HUMAN RELEVANCE OF CLINICAL DEVELOPMENT CANDIDATE
A Westerling-Bui, T Soare, S Venkatachalan, M DeRan, E Fast, A Fanelli, ...
Nephrology Dialysis Transplantation 35 (Supplement_3), gfaa139. SO038, 2020
2020
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