Energy stress regulates hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein M DeRan, J Yang, CH Shen, EC Peters, J Fitamant, P Chan, M Hsieh, ... Cell reports 9 (2), 495-503, 2014 | 336 | 2014 |
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP E Miller, J Yang, M DeRan, C Wu, AI Su, GMC Bonamy, J Liu, EC Peters, ... Chemistry & biology 19 (8), 955-962, 2012 | 305 | 2012 |
Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway PY Chan, X Han, B Zheng, M DeRan, J Yu, GK Jarugumilli, H Deng, ... Nature chemical biology 12 (4), 282-289, 2016 | 266 | 2016 |
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis G Eelen, C Dubois, AR Cantelmo, J Goveia, U Brüning, M DeRan, ... Nature 561 (7721), 63-69, 2018 | 202 | 2018 |
Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A M Pulvino, Y Liang, D Oleksyn, M DeRan, E Van Pelt, J Shapiro, I Sanz, ... Blood, The Journal of the American Society of Hematology 120 (8), 1668-1677, 2012 | 194 | 2012 |
Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors L He, JH Jhong, Q Chen, KY Huang, K Strittmatter, J Kreuzer, M DeRan, ... Cell reports 37 (5), 2021 | 179 | 2021 |
Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ... Cell 170 (1), 199-212. e20, 2017 | 172 | 2017 |
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma EY Chen, MT DeRan, MS Ignatius, KB Grandinetti, R Clagg, KM McCarthy, ... Proceedings of the National Academy of Sciences 111 (14), 5349-5354, 2014 | 152 | 2014 |
Lats1/2 sustain intestinal stem cells and Wnt activation through TEAD-dependent and independent transcription Q Li, Y Sun, GK Jarugumilli, S Liu, K Dang, JL Cotton, J Xiol, PY Chan, ... Cell stem cell 26 (5), 675-692. e8, 2020 | 150 | 2020 |
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity B Chen, B Zheng, M DeRan, GK Jarugumilli, J Fu, YS Brooks, X Wu Nature chemical biology 12 (9), 686-693, 2016 | 110 | 2016 |
2-Bromopalmitate analogues as activity-based probes to explore palmitoyl acyltransferases B Zheng, M DeRan, X Li, X Liao, M Fukata, X Wu Journal of the American Chemical Society 135 (19), 7082-7085, 2013 | 106 | 2013 |
Transcriptional Activation of Histone Genes Requires NPAT-Dependent Recruitment of TRRAP-Tip60 Complex to Histone Promoters during the G1/S Phase … M DeRan, M Pulvino, E Greene, C Su, J Zhao Molecular and cellular biology 28 (1), 435-447, 2008 | 64 | 2008 |
YAP-dependent proliferation by a small molecule targeting annexin A2 SZ Shalhout, PY Yang, EM Grzelak, K Nutsch, S Shao, C Zambaldo, ... Nature Chemical Biology 17 (7), 767-775, 2021 | 43 | 2021 |
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic AD Westerling-Bui, EM Fast, TW Soare, S Venkatachalan, M DeRan, ... Science Advances 8 (27), eabj5633, 2022 | 18 | 2022 |
Chemical Probe to Identify the Cellular Targets of the Reactive Lipid Metabolite 2-trans-Hexadecenal GK Jarugumilli, JR Choi, PY Chan, M Yu, Y Sun, B Chen, J Niu, M DeRan, ... ACS chemical biology 13 (5), 1130-1136, 2018 | 17 | 2018 |
A translational kidney organoid system bolsters human relevance of clinical development candidate A Westerling-Bui, TW Soare, S Venkatachalan, M DeRan, EM Fast, ... bioRxiv, 2019.12. 30.891440, 2019 | 4 | 2019 |
Assessing G1-to-S-Phase Progression After Genotoxic Stress M DeRan, M Pulvino, J Zhao Cell Cycle Checkpoints: Methods and Protocols, 221-230, 2011 | 4 | 2011 |
When small molecules are like real estate: it’s all about location, location, location M DeRan, BK Wagner Cell chemical biology 25 (10), 1169-1170, 2018 | 2 | 2018 |
Colocalization of ovarian cancer-associated biomarkers in tumors, cancer cells and extracellular vesicles AD Couvillon, ES Winn-Deen, S Thornton, S Liu, M DeRan, M Pacula, ... Cancer Research 84 (6_Supplement), 1066-1066, 2024 | 1 | 2024 |
SO038 A TRANSLATIONAL KIDNEY ORGANOID SYSTEM BOLSTERS HUMAN RELEVANCE OF CLINICAL DEVELOPMENT CANDIDATE A Westerling-Bui, T Soare, S Venkatachalan, M DeRan, E Fast, A Fanelli, ... Nephrology Dialysis Transplantation 35 (Supplement_3), gfaa139. SO038, 2020 | | 2020 |