A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice C Escribano-Díaz, A Orthwein, A Fradet-Turcotte, M Xing, JTF Young, ... Molecular cell 49 (5), 872-883, 2013 | 1077 | 2013 |
A genetic map of the response to DNA damage in human cells M Olivieri, T Cho, A Álvarez-Quilón, K Li, MJ Schellenberg, ... Cell 182 (2), 481-496. e21, 2020 | 460 | 2020 |
RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability D Xu, R Guo, A Sobeck, CZ Bachrati, J Yang, T Enomoto, GW Brown, ... Genes & development 22 (20), 2843-2855, 2008 | 224 | 2008 |
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway M Xing, M Yang, W Huo, F Feng, L Wei, W Jiang, S Ning, Z Yan, W Li, ... Nature communications 6 (1), 6233, 2015 | 188 | 2015 |
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation D Xu, W Shen, R Guo, Y Xue, W Peng, J Sima, J Yang, A Sharov, ... Nature neuroscience 16 (9), 1238-1247, 2013 | 173 | 2013 |
Rif1 provides a new DNA‐binding interface for the Bloom syndrome complex to maintain normal replication D Xu, P Muniandy, E Leo, J Yin, S Thangavel, X Shen, M Ii, K Agama, ... The EMBO journal 29 (18), 3140-3155, 2010 | 108 | 2010 |
An OB-fold complex controls the repair pathways for DNA double-strand breaks S Gao, S Feng, S Ning, J Liu, H Zhao, Y Xu, J Shang, K Li, Q Li, R Guo, ... Nature communications 9 (1), 3925, 2018 | 90 | 2018 |
53BP1 and BRCA1 control pathway choice for stalled replication restart Y Xu, S Ning, Z Wei, R Xu, X Xu, M Xing, R Guo, D Xu Elife 6, e30523, 2017 | 82 | 2017 |
Ewing tumor-associated antigen 1 interacts with replication protein A to promote restart of stalled replication forks S Feng, Y Zhao, Y Xu, S Ning, W Huo, M Hou, G Gao, J Ji, R Guo, D Xu Journal of Biological Chemistry 291 (42), 21956-21962, 2016 | 80 | 2016 |
Repair pathway choice for double-strand breaks Y Xu, D Xu Essays in Biochemistry 64 (5), 765-777, 2020 | 72 | 2020 |
RNA topoisomerase is prevalent in all domains of life and associates with polyribosomes in animals M Ahmad, Y Xue, SK Lee, JL Martindale, W Shen, W Li, S Zou, ... Nucleic acids research 44 (13), 6335-6349, 2016 | 72 | 2016 |
Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction M Ahmad, W Shen, W Li, Y Xue, S Zou, D Xu, W Wang Nucleic acids research 45 (5), 2704-2713, 2017 | 70 | 2017 |
Non-homologous end joining: advances and frontiers K Yang, R Guo, D Xu Acta Biochimica et Biophysica Sinica 48 (7), 632-640, 2016 | 70 | 2016 |
Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks C Ling, J Huang, Z Yan, Y Li, M Ohzeki, M Ishiai, D Xu, M Takata, ... Cell discovery 2 (1), 1-18, 2016 | 67 | 2016 |
Remodeling of interstrand crosslink proximal replisomes is dependent on ATR, FANCM, and FANCD2 J Huang, J Zhang, MA Bellani, D Pokharel, J Gichimu, RC James, H Gali, ... Cell reports 27 (6), 1794-1808. e5, 2019 | 63 | 2019 |
The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis W Li, X Bai, J Li, Y Zhao, J Liu, H Zhao, L Liu, M Ding, Q Wang, FY Shi, ... Nature cell biology 21 (10), 1273-1285, 2019 | 56 | 2019 |
Type IA topoisomerases can be “magicians” for both DNA and RNA in all domains of life M Ahmad, D Xu, W Wang RNA biology 14 (7), 854-864, 2017 | 45 | 2017 |
Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome KA Hoadley, D Xu, Y Xue, KA Satyshur, W Wang, JL Keck Structure 18 (9), 1149-1158, 2010 | 45 | 2010 |
Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation R Xu, Y Xu, W Huo, Z Lv, J Yuan, S Ning, Q Wang, M Hou, G Gao, J Ji, ... Proceedings of the National Academy of Sciences 115 (43), E10079-E10088, 2018 | 33 | 2018 |
SMC 5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability F Rossi, A Helbling‐Leclerc, R Kawasumi, NK Jegadesan, X Xu, ... EMBO reports 21 (2), e48222, 2020 | 30 | 2020 |