| A single-cell atlas of human and mouse white adipose tissue MP Emont, C Jacobs, AL Essene, D Pant, D Tenen, G Colleluori, ... Nature 603 (7903), 926-933, 2022 | 482 | 2022 |
| Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity HC Roh, LTY Tsai, M Shao, D Tenen, Y Shen, M Kumari, A Lyubetskaya, ... Cell metabolism 27 (5), 1121-1137. e5, 2018 | 239 | 2018 |
| Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through Growth Differentiation Factor 3 JA Hall, D Ramachandran, HC Roh, JR DiSpirito, T Belchior, PJH Zushin, ... Cell Metabolism 32 (4), 665-675. e6, 2020 | 84 | 2020 |
| IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis S Yan, M Kumari, H Xiao, C Jacobs, S Kochumon, M Jedrychowski, ... The Journal of Clinical Investigation, 2021 | 62 | 2021 |
| Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells J Li, E Li, RS Czepielewski, J Chi, X Guo, YH Han, D Wang, L Wang, B Hu, ... Cell metabolism 33 (7), 1449-1465. e6, 2021 | 57 | 2021 |
| Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling HC Roh, M Kumari, S Taleb, D Tenen, C Jacobs, A Lyubetskaya, LTY Tsai, ... Molecular metabolism 42, 101086, 2020 | 40 | 2020 |
| Mesothelial cells are not a source of adipocytes in mice GP Westcott, MP Emont, J Li, C Jacobs, L Tsai, ED Rosen Cell reports 36 (2), 2021 | 33 | 2021 |
| NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor A Mendoza, I Astapova, H Shimizu, MR Gallop, L Al-Sowaimel, ... Proceedings of the National Academy of Sciences 114 (40), E8458-E8467, 2017 | 27 | 2017 |
| Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP A Mendoza, C Tang, J Choi, M Acuña, M Logan, AG Martin, ... Science signaling 14 (709), eabh3839, 2021 | 26 | 2021 |
| Targeted analysis of glycomics liquid chromatography/mass spectrometry data JM Dreyfuss, C Jacobs, Y Gindin, G Benson, GO Staples, J Zaia Analytical and bioanalytical chemistry 399 (2), 727-735, 2011 | 23 | 2011 |
| Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming CD Holman, AP Sakers, RP Calhoun, L Cheng, EC Fein, C Jacobs, L Tsai, ... Elife 12, RP87756, 2024 | 17 | 2024 |
| Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies S Chandani, C Jacobs, EL Loechler Journal of nucleic acids 2010, 2010 | 16 | 2010 |
| Upon accounting for the impact of isoenzyme loss, gene deletion costs anticorrelate with their evolutionary rates C Jacobs, L Lambourne, Y Xia, D Segrè PloS one 12 (1), e0170164, 2017 | 15 | 2017 |
| A spatially-resolved transcriptional atlas of the murine dorsal pons at single-cell resolution S Nardone, R De Luca, A Zito, N Klymko, D Nicoloutsopoulos, O Amsalem, ... Nature Communications 15 (1), 1966, 2024 | 13 | 2024 |
| Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor EJ Ciampa, P Flahardy, H Srinivasan, C Jacobs, L Tsai, SA Karumanchi, ... Elife 12, RP85597, 2023 | 11 | 2023 |
| Organization principles in genetic interaction networks C Jacobs, D Segre Evolutionary systems biology, 53-78, 2012 | 9 | 2012 |
| A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients Y Pita-Juarez, D Karagkouni, N Kalavros, JC Melms, S Niezen, ... BioRxiv, 2022 | 7 | 2022 |
| Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels S Yan, A Santoro, MJ Niphakis, AM Pinto, CL Jacobs, R Ahmad, ... Nature Communications 15 (1), 4605, 2024 | 4 | 2024 |
| AgRP neuron cis-regulatory analysis across hunger states reveals that IRF3 mediates leptin’s acute effects FD Heyward, N Liu, C Jacobs, NLS Machado, R Ivison, A Uner, ... Nature Communications 15 (1), 4646, 2024 | 3 | 2024 |
Anna LyubetskayaMetaphore BioVerified email at metaphorebio.com