| Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer M Malehmir, D Pfister, S Gallage, M Szydlowska, D Inverso, E Kotsiliti, ... Nature medicine 25 (4), 641-655, 2019 | 370 | 2019 |
| Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner A Lagnado, J Leslie, MH Ruchaud‐Sparagano, S Victorelli, P Hirsova, ... The EMBO journal 40 (9), e106048, 2021 | 167 | 2021 |
| Neutrophils as potential therapeutic targets in hepatocellular carcinoma D Geh, J Leslie, R Rumney, HL Reeves, TG Bird, DA Mann Nature Reviews Gastroenterology & Hepatology 19 (4), 257-273, 2022 | 150 | 2022 |
| CXCR2 inhibition enables NASH-HCC immunotherapy J Leslie, JBG Mackey, T Jamieson, E Ramon-Gil, TM Drake, F Fercoq, ... Gut 71 (10), 2093-2106, 2022 | 130 | 2022 |
| Lipid remodeling in hepatocyte proliferation and hepatocellular carcinoma Z Hall, D Chiarugi, E Charidemou, J Leslie, E Scott, L Pellegrinet, ... Hepatology 73 (3), 1028-1044, 2021 | 122 | 2021 |
| Immunomodulatory effects of lenvatinib plus anti–programmed cell death protein 1 in mice and rationale for patient enrichment in hepatocellular carcinoma L Torrens, C Montironi, M Puigvehí, A Mesropian, J Leslie, PK Haber, ... Hepatology 74 (5), 2652-2669, 2021 | 118 | 2021 |
| Age-associated mitochondrial DNA mutations cause metabolic remodeling that contributes to accelerated intestinal tumorigenesis ALM Smith, JC Whitehall, C Bradshaw, D Gay, F Robertson, AP Blain, ... Nature cancer 1 (10), 976-989, 2020 | 108 | 2020 |
| A bioreactor technology for modeling fibrosis in human and rodent precision‐cut liver slices HL Paish, LH Reed, H Brown, MC Bryan, O Govaere, J Leslie, BS Barksby, ... Hepatology 70 (4), 1377-1391, 2019 | 105 | 2019 |
| Ammonia scavenging prevents progression of fibrosis in experimental nonalcoholic fatty liver disease F De Chiara, KL Thomsen, A Habtesion, H Jones, N Davies, ... Hepatology 71 (3), 874-892, 2020 | 95 | 2020 |
| A proof-of-concept for epigenetic therapy of tissue fibrosis: inhibition of liver fibrosis progression by 3-deazaneplanocin A M Zeybel, S Luli, L Sabater, T Hardy, F Oakley, J Leslie, A Page, ... Molecular Therapy 25 (1), 218-231, 2017 | 82 | 2017 |
| FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis J Leslie, BJM Millar, A del Carpio Pons, RA Burgoyne, JD Frost, ... JCI insight 5 (4), e125937, 2020 | 76 | 2020 |
| Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease C Fox, P Cocchiaro, F Oakley, R Howarth, K Callaghan, J Leslie, S Luli, ... Scientific Reports 6 (1), 20101, 2016 | 74 | 2016 |
| c-Rel and its many roles in cancer: an old story with new twists JE Hunter, J Leslie, ND Perkins British journal of cancer 114 (1), 1-6, 2016 | 66 | 2016 |
| Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease CL Wilson, LB Murphy, J Leslie, S Kendrick, J French, CR Fox, ... Journal of hepatology 63 (6), 1421-1428, 2015 | 63 | 2015 |
| Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis M Vacca, J Leslie, S Virtue, BYH Lam, O Govaere, D Tiniakos, S Snow, ... Nature metabolism 2 (6), 514-531, 2020 | 51 | 2020 |
| The exercise IL-6 enigma in cancer ST Orange, J Leslie, M Ross, DA Mann, H Wackerhage Trends in Endocrinology & Metabolism 34 (11), 749-763, 2023 | 39 | 2023 |
| A mammalian target of rapamycin‐perilipin 3 (mTORC1‐Plin3) pathway is essential to activate lipophagy and protects against hepatosteatosis M Garcia‐Macia, A Santos‐Ledo, J Leslie, HL Paish, AL Collins, RS Scott, ... Hepatology 74 (6), 3441-3459, 2021 | 39 | 2021 |
| A RelA (p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer A Moles, JA Butterworth, A Sanchez, JE Hunter, J Leslie, H Sellier, ... Oncogene 35 (35), 4623-4632, 2016 | 38 | 2016 |
| Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression V Azzu, M Vacca, I Kamzolas, Z Hall, J Leslie, S Carobbio, S Virtue, ... Molecular metabolism 48, 101210, 2021 | 37 | 2021 |
| c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis J Leslie, MG Macia, S Luli, JC Worrell, WJ Reilly, HL Paish, A Knox, ... Nature metabolism 2 (11), 1350-1367, 2020 | 36 | 2020 |
