| Kinetically guided radical-based synthesis of C(sp3)−C(sp3) linkages on DNA J Wang, H Lundberg, S Asai, P Martín-Acosta, JS Chen, S Brown, ... Proceedings of the National Academy of Sciences 115 (28), E6404-E6410, 2018 | 151 | 2018 |
| Employing Photoredox Catalysis for DNA‐Encoded Chemistry: Decarboxylative Alkylation of α‐Amino Acids DK Kölmel, RP Loach, T Knauber, ME Flanagan ChemMedChem 13 (20), 2159-2165, 2018 | 104 | 2018 |
| Olefin cross-metathesis as a tool in natural product degradation. The stereochemistry of (+)-falcarindiol AS Ratnayake, T Hemscheidt Organic Letters 4 (26), 4667-4669, 2002 | 98 | 2002 |
| Nomofungin: a new microfilament disrupting agent. AS Ratnayake, WY Yoshida, SL Mooberry, TK Hemscheidt The Journal of Organic Chemistry 66 (26), 8717-8721, 2001 | 91 | 2001 |
| Theopapuamide, a Cyclic Depsipeptide from a Papua New Guinea Lithistid Sponge Theonella swinhoei AS Ratnayake, TS Bugni, X Feng, MK Harper, JJ Skalicky, KA Mohammed, ... Journal of natural products 69 (11), 1582-1586, 2006 | 90 | 2006 |
| On-DNA decarboxylative arylation: merging photoredox with nickel catalysis in water DK Kölmel, J Meng, MH Tsai, J Que, RP Loach, T Knauber, J Wan, ... ACS Combinatorial Science 21 (8), 588-597, 2019 | 88 | 2019 |
| Optimization of tubulysin antibody–drug conjugates: a case study in addressing ADC metabolism LN Tumey, CA Leverett, B Vetelino, F Li, B Rago, X Han, F Loganzo, ... ACS Medicinal Chemistry Letters 7 (11), 977-982, 2016 | 84 | 2016 |
| The structure of microcarpalide, a microfilament disrupting agent from an endophytic fungus AS Ratnayake, WY Yoshida, SL Mooberry, T Hemscheidt Organic Letters 3 (22), 3479-3481, 2001 | 83 | 2001 |
| Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues H He, AS Ratnayake, JE Janso, M He, HY Yang, F Loganzo, B Shor, ... Journal of natural products 77 (8), 1864-1870, 2014 | 75 | 2014 |
| Spliceostatin hemiketal biosynthesis in Burkholderia spp. is catalyzed by an iron/α-ketoglutarate–dependent dioxygenase AS Eustáquio, JE Janso, AS Ratnayake, CJ O’Donnell, FE Koehn Proceedings of the National Academy of Sciences 111 (33), E3376-E3385, 2014 | 75 | 2014 |
| Ultra-high-throughput acoustic droplet ejection-open port interface-mass spectrometry for parallel medicinal chemistry KJ DiRico, W Hua, C Liu, JW Tucker, AS Ratnayake, ME Flanagan, ... ACS Medicinal Chemistry Letters 11 (6), 1101-1110, 2020 | 66 | 2020 |
| Merging C (sp 3)–H activation with DNA-encoding Z Fan, S Zhao, T Liu, PX Shen, ZN Cui, Z Zhuang, Q Shao, JS Chen, ... Chemical Science 11 (45), 12282-12288, 2020 | 66 | 2020 |
| Up-regulation of CYP26A1 in Adenomatous Polyposis Coli–deficient vertebrates via a WNT-dependent mechanism: Implications for intestinal cell differentiation and colon tumor … DN Shelton, IT Sandoval, A Eisinger, S Chidester, A Ratnayake, ... Cancer Research 66 (15), 7571-7577, 2006 | 64 | 2006 |
| Photocatalytic [2+ 2] cycloaddition in DNA-encoded chemistry DK Kölmel, AS Ratnayake, ME Flanagan, MH Tsai, C Duan, C Song Organic letters 22 (8), 2908-2913, 2020 | 61 | 2020 |
| Aurantosides G, H, and I: Three New Tetramic Acid Glycosides from a Papua New Guinea Theonella swinhoei AS Ratnayake, RA Davis, MK Harper, CA Veltri, CD Andjelic, LR Barrows, ... Journal of natural products 68 (1), 104-107, 2005 | 49 | 2005 |
| A solution phase platform to characterize chemical reaction compatibility with DNA-encoded chemical library synthesis AS Ratnayake, ME Flanagan, TL Foley, JD Smith, JG Johnson, ... ACS combinatorial science 21 (10), 650-655, 2019 | 47 | 2019 |
| Photoredox cross-electrophile coupling in DNA-encoded chemistry DK Kölmel, AS Ratnayake, ME Flanagan Biochemical and Biophysical Research Communications 533 (2), 201-208, 2020 | 44 | 2020 |
| Selecting approaches for hit identification and increasing options by building the efficient discovery of actionable chemical matter from DNA-encoded libraries TL Foley, W Burchett, Q Chen, ME Flanagan, B Kapinos, X Li, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (2), 263-280, 2021 | 38 | 2021 |
| Nomofungin: A New Microfilament Disrupting Agent. AS Ratnayake, WY Yoshida, SL Mooberry, TK Hemscheidt The Journal of Organic Chemistry 68 (4), 1640-1640, 2003 | 38 | 2003 |
| Evaluating Indole-Related Derivatives as Precursors in the Directed Biosynthesis of Diazepinomicin Analogues§ AS Ratnayake, JE Janso, X Feng, G Schlingmann, I Goljer, GT Carter Journal of natural products 72 (3), 496-499, 2009 | 25 | 2009 |