Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio I Kuperstein, K Broersen, I Benilova, J Rozenski, W Jonckheere, ... The EMBO journal 29 (19), 3408-3420, 2010 | 664 | 2010 |
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity P Van Damme, E Bogaert, M Dewil, N Hersmus, D Kiraly, W Scheveneels, ... Proceedings of the National Academy of Sciences 104 (37), 14825-14830, 2007 | 282 | 2007 |
GluR2 deficiency accelerates motor neuron degeneration in a mouse model of amyotrophic lateral sclerosis P Van Damme, D Braeken, G Callewaert, W Robberecht, ... Journal of Neuropathology & Experimental Neurology 64 (7), 605-612, 2005 | 155 | 2005 |
Single-cell recording and stimulation with a 16k micro-nail electrode array integrated on a 0.18 μm CMOS chip R Huys, D Braeken, D Jans, A Stassen, N Collaert, J Wouters, J Loo, ... Lab on a Chip 12 (7), 1274-1280, 2012 | 112 | 2012 |
A multimodal CMOS MEA for high-throughput intracellular action potential measurements and impedance spectroscopy in drug-screening applications CM Lopez, HS Chun, S Wang, L Berti, J Putzeys, C Van Den Bulcke, ... IEEE Journal of Solid-State Circuits 53 (11), 3076-3086, 2018 | 107 | 2018 |
And then there was light: perspectives of optogenetics for deep brain stimulation and neuromodulation J Delbeke, L Hoffman, K Mols, D Braeken, D Prodanov Frontiers in neuroscience 11, 663, 2017 | 102 | 2017 |
Substrate topography determines neuronal polarization and growth in vitro L Micholt, A Gärtner, D Prodanov, D Braeken, CG Dotti, C Bartic PloS one 8 (6), e66170, 2013 | 98 | 2013 |
A multichannel integrated circuit for electrical recording of neural activity, with independent channel programmability CM Lopez, D Prodanov, D Braeken, I Gligorijevic, W Eberle, C Bartic, ... IEEE transactions on biomedical circuits and systems 6 (2), 101-110, 2012 | 87 | 2012 |
High-density electrical recording and impedance imaging with a multi-modal CMOS multi-electrode array chip B Miccoli, CM Lopez, E Goikoetxea, J Putzeys, M Sekeri, O Krylychkina, ... Frontiers in neuroscience 13, 641, 2019 | 83 | 2019 |
Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons AA Ungureanu, I Benilova, O Krylychkina, D Braeken, B De Strooper, ... Scientific reports 6 (1), 25841, 2016 | 74 | 2016 |
Building blocks for a European Organ-on-Chip roadmap M Mastrangeli, S Millet, C Mummery, P Loskill, D Braeken, W Eberle, ... ALTEX-Alternatives to animal experimentation 36 (3), 481-492, 2019 | 65 | 2019 |
Superimposed topographic and chemical cues synergistically guide neurite outgrowth A Kundu, L Micholt, S Friedrich, DR Rand, C Bartic, D Braeken, ... Lab on a Chip 13 (15), 3070-3081, 2013 | 62 | 2013 |
Pixel super-resolution for lens-free holographic microscopy using deep learning neural networks Z Luo, A Yurt, R Stahl, A Lambrechts, V Reumers, D Braeken, L Lagae Optics express 27 (10), 13581-13595, 2019 | 61 | 2019 |
Brain-on-a-chip devices for drug screening and disease modeling applications B Miccoli, D Braeken, YCE Li Current pharmaceutical design 24 (45), 5419-5436, 2018 | 61 | 2018 |
A micropatterned multielectrode shell for 3D spatiotemporal recording from live cells J Cools, Q Jin, E Yoon, D Alba Burbano, Z Luo, D Cuypers, G Callewaert, ... Advanced Science 5 (4), 1700731, 2018 | 58 | 2018 |
An integrated multi-electrode-optrode array for in vitro optogenetics M Welkenhuysen, L Hoffman, Z Luo, A De Proft, C Van den Haute, ... Scientific reports 6 (1), 1-10, 2016 | 57 | 2016 |
Low loss CMOS-compatible PECVD silicon nitride waveguides and grating couplers for blue light optogenetic applications L Hoffman, A Subramanian, P Helin, B Du Bois, R Baets, P Van Dorpe, ... IEEE Photonics Journal 8 (5), 1-11, 2016 | 45 | 2016 |
Open-cell recording of action potentials using active electrode arrays D Braeken, D Jans, R Huys, A Stassen, N Collaert, L Hoffman, W Eberle, ... Lab on a Chip 12 (21), 4397-4402, 2012 | 45 | 2012 |
Proximal and distal modulation of neural activity by spatially confined optogenetic activation with an integrated high-density optoelectrode S Libbrecht, L Hoffman, M Welkenhuysen, C Van den Haute, ... Journal of Neurophysiology 120 (1), 149-161, 2018 | 41 | 2018 |
Single-cell transfection technologies for cell therapies and gene editing B Duckert, S Vinkx, D Braeken, M Fauvart Journal of Controlled Release 330, 963-975, 2021 | 37 | 2021 |