| Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3595 | 2017 |
| Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia M Kulis, S Heath, M Bibikova, AC Queirós, A Navarro, G Clot, ... Nature genetics 44 (11), 1236-1242, 2012 | 692 | 2012 |
| Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 606 | 2017 |
| Self-organization and symmetry breaking in intestinal organoid development D Serra, U Mayr, A Boni, I Lukonin, M Rempfler, L Challet Meylan, ... Nature 569 (7754), 66-72, 2019 | 510 | 2019 |
| Cell types of the human retina and its organoids at single-cell resolution CS Cowan, M Renner, M De Gennaro, B Gross-Scherf, D Goldblum, ... Cell 182 (6), 1623-1640. e34, 2020 | 506 | 2020 |
| The spliceosome: the ultimate RNA chaperone and sculptor P Papasaikas, J Valcárcel Trends in biochemical sciences 41 (1), 33-45, 2016 | 296 | 2016 |
| Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia PG Ferreira, P Jares, D Rico, G Gómez-López, A Martínez-Trillos, ... Genome research 24 (2), 212-226, 2014 | 260 | 2014 |
| Functional Splicing Network Reveals Extensive Regulatory Potential of the Core Spliceosomal Machinery P Papasaikas, JR Tejedor, L Vigevani, J Valcárcel Molecular cell 57 (1), 7-22, 2015 | 193 | 2015 |
| Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 184 | 2017 |
| UNR/CSDE1 drives a post-transcriptional program to promote melanoma invasion and metastasis L Wurth, P Papasaikas, D Olmeda, N Bley, GT Calvo, S Guerrero, ... Cancer cell 30 (5), 694-707, 2016 | 173 | 2016 |
| Genome-wide identification of Fas/CD95 alternative splicing regulators reveals links with iron homeostasis JR Tejedor, P Papasaikas, J Valcárcel Molecular cell 57 (1), 23-38, 2015 | 99 | 2015 |
| A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models NG Sgourakis, PG Bagos, PK Papasaikas, SJ Hamodrakas BMC bioinformatics 6, 1-12, 2005 | 74 | 2005 |
| Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis F Yang, J Wang, BL Pierce, LS Chen, F Aguet, KG Ardlie, BB Cummings, ... Genome research 27 (11), 1859-1871, 2017 | 71 | 2017 |
| Local genetic effects on gene expression across 44 human tissues F Aguet, AA Brown, SE Castel, JR Davis, P Mohammadi, AV Segre, ... BioRxiv, 074450, 2016 | 65 | 2016 |
| PRED-GPCR: GPCR recognition and family classification server PK Papasaikas, PG Bagos, ZI Litou, VJ Promponas, SJ Hamodrakas Nucleic acids research 32 (suppl_2), W380-W382, 2004 | 63 | 2004 |
| A novel method for GPCR recognition and family classification from sequence alone using signatures derived from profile hidden Markov models PK Papasaikas, PG Bagos, ZI Litou, SJ Hamodrakas SAR and QSAR in Environmental Research 14 (5-6), 413-420, 2003 | 48 | 2003 |
| Relationship between nucleosome positioning and progesterone-induced alternative splicing in breast cancer cells C Iannone, A Pohl, P Papasaikas, D Soronellas, GP Vicent, M Beato, ... Rna 21 (3), 360-374, 2015 | 44 | 2015 |
| Impaired spermatogenesis, muscle, and erythrocyte function in U12 intron splicing-defective Zrsr1 mutant mice K Horiuchi, S Perez-Cerezales, P Papasaikas, P Ramos-Ibeas, ... Cell reports 23 (1), 143-155, 2018 | 43 | 2018 |
| The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 T Welte, AC Tuck, P Papasaikas, SH Carl, M Flemr, P Knuckles, ... Genes & development 33 (17-18), 1221-1235, 2019 | 40 | 2019 |
| Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns S Keiper, P Papasaikas, CL Will, J Valcárcel, C Girard, R Lührmann Nature communications 10 (1), 3639, 2019 | 33 | 2019 |
Juan ValcarcelICREA Research Professor, Center for Genomic RegulationVerified email at crg.eu