| A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release C Alcaino, KR Knutson, AJ Treichel, G Yildiz, PR Strege, DR Linden, JH Li, ... Proceedings of the National Academy of Sciences 115 (32), E7632-E7641, 2018 | 240 | 2018 |
| Mechanical stretch increases expression of CXCL1 in liver sinusoidal endothelial cells to recruit neutrophils, generate sinusoidal microthombi, and promote portal hypertension MB Hilscher, T Sehrawat, JP Arab, Z Zeng, J Gao, M Liu, E Kostallari, ... Gastroenterology 157 (1), 193-209. e9, 2019 | 195 | 2019 |
| Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces DA Simonetto, H Yang, M Yin, TM de Assuncao, JH Kwon, M Hilscher, ... Hepatology 61 (2), 648-659, 2015 | 193 | 2015 |
| Mechanosensitivity of Nav1.5, a voltage‐sensitive sodium channel A Beyder, JL Rae, C Bernard, PR Strege, F Sachs, G Farrugia The Journal of physiology 588 (24), 4969-4985, 2010 | 186 | 2010 |
| Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces F Wang, K Knutson, C Alcaino, DR Linden, SJ Gibbons, P Kashyap, ... The Journal of physiology 595 (1), 79-91, 2017 | 182 | 2017 |
| Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing V Butin-Israeli, TM Bui, HL Wiesolek, L Mascarenhas, JJ Lee, LC Mehl, ... The Journal of clinical investigation 129 (2), 712-726, 2019 | 180 | 2019 |
| Loss-of-function of the voltage-gated sodium channel NaV1. 5 (channelopathies) in patients with irritable bowel syndrome A Beyder, A Mazzone, PR Strege, DJ Tester, YA Saito, CE Bernard, ... Gastroenterology 146 (7), 1659-1668, 2014 | 175 | 2014 |
| Altered expression of Ano1 variants in human diabetic gastroparesis A Mazzone, CE Bernard, PR Strege, A Beyder, LJV Galietta, PJ Pasricha, ... Journal of Biological Chemistry 286 (15), 13393-13403, 2011 | 118 | 2011 |
| Mechanosensory signaling in enterochromaffin cells and 5-HT release: potential implications for gut inflammation A Linan-Rico, F Ochoa-Cortes, A Beyder, S Soghomonyan, ... Frontiers in neuroscience 10, 564, 2016 | 113 | 2016 |
| Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT3 receptor expression via acetate production Y Bhattarai, BA Schmidt, DR Linden, ED Larson, M Grover, A Beyder, ... American journal of physiology-Gastrointestinal and liver physiology 313 (1 …, 2017 | 110 | 2017 |
| Targeting ion channels for the treatment of gastrointestinal motility disorders A Beyder, G Farrugia Therapeutic advances in gastroenterology 5 (1), 5-21, 2012 | 98 | 2012 |
| The bioelectrical basis and validity of gastrointestinal extracellular slow wave recordings TR Angeli, P Du, N Paskaranandavadivel, PWM Janssen, A Beyder, ... The Journal of physiology 591 (18), 4567-4579, 2013 | 92 | 2013 |
| Mechanosensitive piezo channels in the gastrointestinal tract C Alcaino, G Farrugia, A Beyder Current topics in membranes 79, 219-244, 2017 | 86 | 2017 |
| Gut feelings: mechanosensing in the gastrointestinal tract A Mercado-Perez, A Beyder Nature Reviews Gastroenterology & Hepatology 19 (5), 283-296, 2022 | 77 | 2022 |
| Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4 C Alcaino, K Knutson, PA Gottlieb, G Farrugia, A Beyder Channels 11 (3), 245-253, 2017 | 76 | 2017 |
| Ranolazine Decreases Mechanosensitivity of the Voltage-Gated Sodium Ion Channel NaV1.5: A Novel Mechanism of Drug Action A Beyder, PR Strege, S Reyes, CE Bernard, A Terzic, J Makielski, ... Circulation 125 (22), 2698-2706, 2012 | 75 | 2012 |
| Lack of serotonin 5‐HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo VS Tharayil, MM Wouters, JE Stanich, JL Roeder, S Lei, A Beyder, ... Neurogastroenterology & Motility 22 (4), 462-e110, 2010 | 73 | 2010 |
| Biophysically based modeling of the interstitial cells of Cajal: current status and future perspectives R Lees-Green, P Du, G O’Grady, A Beyder, G Farrugia, AJ Pullan Frontiers in physiology 2, 29, 2011 | 68 | 2011 |
| Atomic force microscopy analysis of cell volume regulation C Spagnoli, A Beyder, S Besch, F Sachs Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 78 (3 …, 2008 | 68 | 2008 |
| Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased NaV1.5 current and mechanosensitivity PR Strege, A Mazzone, CE Bernard, L Neshatian, SJ Gibbons, YA Saito, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 314 (4 …, 2018 | 58 | 2018 |
Constanza AlcainoUniversity of CambridgeVerified email at medschl.cam.ac.uk
