| ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation J Monypenny, H Milewicz, F Flores-Borja, G Weitsman, A Cheung, ... Cell Reports 24 (3), 630-641, 2018 | 132 | 2018 |
| RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers S Irshad, F Flores-Borja, K Lawler, J Monypenny, R Evans, V Male, ... Cancer Research 77 (5), 1083-1096, 2017 | 129 | 2017 |
| MicroRNA‐196a promotes an oncogenic effect in head and neck cancer cells by suppressing annexin A1 and enhancing radioresistance YE Suh, N Raulf, J Gäken, K Lawler, TG Urbano, J Bullenkamp, S Gobeil, ... International Journal of Cancer 137 (5), 1021-1034, 2015 | 109 | 2015 |
| A transcriptomic signature of the hypothalamic response to fasting and BDNF deficiency in Prader-Willi syndrome E Bochukova, K Lawler, S Croizier, JM Keogh, N Patel, G Strohbehn, ... Cell Reports 22 (13), 3401-3408, 2018 | 101 | 2018 |
| Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis Y Yang, AA van der Klaauw, L Zhu, TM Cacciottolo, Y He, LKJ Stadler, ... Nature Communications 10 (1), 1718, 2019 | 67 | 2019 |
| How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology GO Fruhwirth, LP Fernandes, G Weitsman, G Patel, M Kelleher, K Lawler, ... Chemphyschem 12 (3), 442-461, 2011 | 64 | 2011 |
| Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer R Evans, F Flores-Borja, S Nassiri, E Miranda, K Lawler, A Grigoriadis, ... Cell Reports 27 (7), 1967-1978. e4, 2019 | 52 | 2019 |
| The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility T Kiuchi, E Ortiz-Zapater, J Monypenny, DR Matthews, LK Nguyen, ... Science signaling 7 (339), ra78-ra78, 2014 | 44 | 2014 |
| HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status G Weitsman, PR Barber, LK Nguyen, K Lawler, G Patel, N Woodman, ... Oncotarget 7 (32), 51012-51026, 2016 | 39 | 2016 |
| The use of molecular imaging combined with genomic techniques to understand the heterogeneity in cancer metastasis R Chowdhury, B Ganeshan, S Irshad, K Lawler, M Eisenblätter, ... The British journal of radiology 87 (1037), 20140065, 2014 | 36 | 2014 |
| Contributions of transcription and mRNA decay to gene expression dynamics of fission yeast in response to oxidative stress S Marguerat, K Lawler, A Brazma, J Bähler RNA biology 11 (6), 702-714, 2014 | 35 | 2014 |
| Leptin-mediated changes in the human metabolome K Lawler, I Huang-Doran, T Sonoyama, TH Collet, JM Keogh, E Henning, ... JCEM, https://doi.org/10.1210/clinem/dgaa251, 2020 | 32 | 2020 |
| DART: Denoising Algorithm based on Relevance network Topology improves molecular pathway activity inference Y Jiao, K Lawler, GS Patel, A Purushotham, AF Jones, A Grigoriadis, ... BMC bioinformatics 12 (1), 403, 2011 | 32 | 2011 |
| Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior Y He, B Brouwers, H Liu, H Liu, K Lawler, E Mendes de Oliveira, DK Lee, ... Nature Medicine 28 (12), 2537-2546, 2022 | 30 | 2022 |
| Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma Y Suh, K Lawler, R Henley-Smith, L Pike, R Leek, S Barrington, EW Odell, ... British Journal of Cancer 116 (8), 1057-1064, 2017 | 25 | 2017 |
| Memory effects in biochemical networks as the natural counterpart of extrinsic noise KJ Rubin, K Lawler, P Sollich, T Ng Journal of theoretical biology 357, 245-267, 2014 | 24 | 2014 |
| Genomic clustering and co-regulation of transcriptional networks in the pathogenic fungus Fusarium graminearum K Lawler, K Hammond-Kosack, A Brazma, RMR Coulson BMC systems biology 7 (1), 52, 2013 | 23 | 2013 |
| Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans JM Vicencio, R Evans, R Green, Z An, J Deng, C Treacy, R Mustapha, ... Cell Death & Disease 13 (3), 1-14, 2022 | 21 | 2022 |
| The challenges of integrating molecular imaging into the optimization of cancer therapy GS Patel, T Kiuchi, K Lawler, E Ofo, GO Fruhwirth, M Kelleher, E Shamil, ... Integrative Biology 3 (6), 603-631, 2011 | 21 | 2011 |
| Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila N Agrawal, K Lawler, CM Davidson, JM Keogh, R Legg, INTERVAL, ... PLoS Biology 19 (11), e3001255, 2021 | 19 | 2021 |
