Cellular senescence drives age-dependent hepatic steatosis M Ogrodnik, S Miwa, T Tchkonia, D Tiniakos, CL Wilson, A Lahat, CP Day, ... Nature communications 8 (1), 15691, 2017 | 911 | 2017 |
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 829 | 2014 |
Mitochondria are required for pro‐ageing features of the senescent phenotype C Correia‐Melo, FDM Marques, R Anderson, G Hewitt, R Hewitt, J Cole, ... The EMBO journal 35 (7), 724-742, 2016 | 715 | 2016 |
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis AM Elsharkawy, F Oakley, DA Mann Apoptosis 10, 927-939, 2005 | 634 | 2005 |
Clinical evidence for the regression of liver fibrosis EL Ellis, DA Mann Journal of hepatology 56 (5), 1171-1180, 2012 | 532 | 2012 |
Nuclear factor‐κB and the hepatic inflammation‐fibrosis‐cancer axis AM Elsharkawy, DA Mann Hepatology 46 (2), 590-597, 2007 | 504 | 2007 |
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats MC Wright, R Issa, DE Smart, N Trim, GI Murray, JN Primrose, MJP Arthur, ... Gastroenterology 121 (3), 685-698, 2001 | 458 | 2001 |
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis J Mann, DCK Chu, A Maxwell, F Oakley, NL Zhu, H Tsukamoto, DA Mann Gastroenterology 138 (2), 705-714. e4, 2010 | 451 | 2010 |
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis F Oakley, M Meso, JP Iredale, K Green, CJ Marek, X Zhou, MJ May, ... Gastroenterology 128 (1), 108-120, 2005 | 380 | 2005 |
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer M Malehmir, D Pfister, S Gallage, M Szydlowska, D Inverso, E Kotsiliti, ... Nature medicine 25 (4), 641-655, 2019 | 360 | 2019 |
Multigenerational epigenetic adaptation of the hepatic wound-healing response M Zeybel, T Hardy, YK Wong, JC Mathers, CR Fox, A Gackowska, ... Nature medicine 18 (9), 1369-1377, 2012 | 319 | 2012 |
Transcriptional regulation of hepatic stellate cell activation DA Mann, DE Smart Gut 50 (6), 891-896, 2002 | 302 | 2002 |
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis J Mann, F Oakley, F Akiboye, A Elsharkawy, AW Thorne, DA Mann Cell Death & Differentiation 14 (2), 275-285, 2007 | 301 | 2007 |
A molecular rheostat: Co-operative rev binding to stem I of the Rev-response element modulates human immunodeficiency virus type-1 late gene expression DA Mann, I Mikaélian, RW Zemmel, SM Green, AD Lowe, T Kimura, ... Journal of molecular biology 241 (2), 193-207, 1994 | 262 | 1994 |
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease MR Ebrahimkhani, F Oakley, LB Murphy, J Mann, A Moles, MJ Perugorria, ... Nature medicine 17 (12), 1668-1673, 2011 | 241 | 2011 |
A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis RG Ruddell, F Oakley, Z Hussain, I Yeung, LJ Bryan-Lluka, GA Ramm, ... The American journal of pathology 169 (3), 861-876, 2006 | 241 | 2006 |
Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs P Doherty, LH Rowett, SE Moore, DA Mann, FS Walsh Neuron 6 (2), 247-258, 1991 | 237 | 1991 |
Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease T Hardy, M Zeybel, CP Day, C Dipper, S Masson, S McPherson, ... Gut 66 (7), 1321-1328, 2017 | 224 | 2017 |
Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 622 (7983), 627-636, 2023 | 217 | 2023 |
Tissue inhibitors of metalloproteinases, hepatic stellate cells and liver fibrosis MJP Arthur, DA Mann, JP Iredale Journal of gastroenterology and hepatology 13 (S1), S33-S38, 1998 | 216 | 1998 |