Development of resazurin microtiter assay for drug sensibility testing of Trypanosoma cruzi epimastigotes M Rolón, C Vega, JA Escario, A Gómez-Barrio Parasitology research 99, 103-107, 2006 | 203 | 2006 |
In vitro screening of American plant extracts on Trypanosoma cruzi and Trichomonas vaginalis S Muelas-Serrano, JJ Nogal, RA Martınez-Dıaz, JA Escario, ... Journal of Ethnopharmacology 71 (1-2), 101-107, 2000 | 151 | 2000 |
Novel Antiprotozoal Products: Imidazole and Benzimidazole N‐Oxide Derivatives and Related Compounds G Aguirre, M Boiani, H Cerecetto, A Gerpe, M González, YF Sainz, ... Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2004 | 106 | 2004 |
A new pharmacological screening assay with Trypanosoma cruzi epimastigotes expressing β-galactosidase C Vega, M Rolón, AR Martínez-Fernández, JA Escario, A Gómez-Barrio Parasitology Research 95, 296-298, 2005 | 98 | 2005 |
Selective activity of polyene macrolides produced by genetically modified Streptomyces on Trypanosoma cruzi M Rolón, EM Seco, C Vega, JJ Nogal, JA Escario, A Gómez-Barrio, ... International Journal of Antimicrobial Agents 28 (2), 104-109, 2006 | 91 | 2006 |
A linear discrimination analysis based virtual screening of trichomonacidal lead-like compounds: outcomes of in silico studies supported by experimental results A Meneses-Marcel, Y Marrero-Ponce, Y Machado-Tugores, ... Bioorganic & medicinal chemistry letters 15 (17), 3838-3843, 2005 | 89 | 2005 |
Predicting antitrichomonal activity: a computational screening using atom-based bilinear indices and experimental proofs Y Marrero-Ponce, A Meneses-Marcel, JA Castillo-Garit, ... Bioorganic & medicinal chemistry 14 (19), 6502-6524, 2006 | 80 | 2006 |
Biological characterization of Trypanosoma cruzi strains RA Martínez-Díaz, JA Escario, JJ Nogal-Ruiz, A Gómez-Barrio Memórias do Instituto Oswaldo Cruz 96, 53-59, 2001 | 72 | 2001 |
A novel non-stochastic quadratic fingerprints-based approach for the ‘in silico’discovery of new antitrypanosomal compounds A Montero-Torres, MC Vega, Y Marrero-Ponce, M Rolón, A Gómez-Barrio, ... Bioorganic & medicinal chemistry 13 (22), 6264-6275, 2005 | 67 | 2005 |
Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1, 2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug MC Vega, M Rolón, A Montero-Torres, C Fonseca-Berzal, JA Escario, ... European journal of medicinal chemistry 58, 214-227, 2012 | 64 | 2012 |
A computer-based approach to the rational discovery of new trichomonacidal drugs by atom-type linear indices Y Marrero-Ponce, Y Machado-Tugores, DM Pereira, JA Escario, ... Current Drug Discovery Technologies 2 (4), 245-265, 2005 | 56 | 2005 |
Biological characterization of a beta-galactosidase expressing clone of Trypanosoma cruzi CL strain A Le-Senne, S Muelas-Serrano, C Fernández-Portillo, JA Escario, ... Memórias do Instituto Oswaldo Cruz 97, 1101-1105, 2002 | 54 | 2002 |
Synthesis, structure and anti-fungal activity of 3-(2′-nitrovinyl) indoles L Canoira, JG Rodriguez, JB Subirats, JA Escario, I Jimenez, ... European journal of medicinal chemistry 24 (1), 39-42, 1989 | 52 | 1989 |
Saponinas esteroidales de la planta Agave brittoniana (Agavaceae) con actividad contra el parásito Trichomona vaginalis J Orestes Guerra, A Meneses, AM Simonet, FA Macías, C Nogueiras, ... Revista de Biología Tropical 56 (4), 1645-1652, 2008 | 51 | 2008 |
Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase C Fonseca-Berzal, DRM Arenas, ARR Bohórquez, JA Escario, ... Bioorganic & medicinal chemistry letters 23 (17), 4851-4856, 2013 | 50 | 2013 |
New ligand-based approach for the discovery of antitrypanosomal compounds MC Vega, A Montero-Torres, Y Marrero-Ponce, M Rolón, A Gómez-Barrio, ... Bioorganic & medicinal chemistry letters 16 (7), 1898-1904, 2006 | 50 | 2006 |
Development of novel benznidazole formulations: physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease R Palmeiro-Roldán, C Fonseca-Berzal, A Gómez-Barrio, VJ Arán, ... International journal of pharmaceutics 472 (1-2), 110-117, 2014 | 49 | 2014 |
Bond-based linear indices in QSAR: computational discovery of novel anti-trichomonal compounds Y Marrero-Ponce, A Meneses-Marcel, OM Rivera-Borroto, ... Journal of Computer-Aided Molecular Design 22, 523-540, 2008 | 47 | 2008 |
Novel solid dispersions of benznidazole: preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system C Fonseca-Berzal, R Palmeiro-Roldan, JA Escario, S Torrado, VJ Aran, ... Experimental parasitology 149, 84-91, 2015 | 43 | 2015 |
Biological variability in clinical isolates of Trichomonas vaginalis A Gómez-Barrio, JJ Nogal-Ruiz, D Montero-Pereira, E Rodríguez-Gallego, ... Memórias do Instituto Oswaldo Cruz 97, 893-896, 2002 | 41 | 2002 |