| Polymer–drug conjugates as nano-sized medicines F Canal, J Sanchis, MJ Vicent Current opinion in biotechnology 22 (6), 894-900, 2011 | 194 | 2011 |
| Directed evolution of an enantioselective epoxide hydrolase: uncovering the source of enantioselectivity at each evolutionary stage MT Reetz, M Bocola, LW Wang, J Sanchis, A Cronin, M Arand, J Zou, ... Journal of the American chemical society 131 (21), 7334-7343, 2009 | 173 | 2009 |
| Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates J Sanchis, L Fernández, JD Carballeira, J Drone, Y Gumulya, ... Applied microbiology and biotechnology 81, 387-397, 2008 | 156 | 2008 |
| Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel A Eldar-Boock, K Miller, J Sanchis, R Lupu, MJ Vicent, R Satchi-Fainaro Biomaterials 32 (15), 3862-3874, 2011 | 143 | 2011 |
| A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes F Cadet, N Fontaine, G Li, J Sanchis, M Ng Fuk Chong, R Pandjaitan, ... Scientific reports 8 (1), 16757, 2018 | 125 | 2018 |
| Polymer–drug conjugates for novel molecular targets J Sanchis, F Canal, R Lucas, MJ Vicent Nanomedicine 5 (6), 915-935, 2010 | 112 | 2010 |
| Constructing and analyzing the fitness landscape of an experimental evolutionary process MT Reetz, J Sanchis ChemBioChem 9 (14), 2260-2267, 2008 | 103 | 2008 |
| Cyclic peptide–polymer nanotubes as efficient and highly potent drug delivery systems for organometallic anticancer complexes SC Larnaudie, JC Brendel, I Romero-Canelón, C Sanchez-Cano, ... Biomacromolecules 19 (1), 239-247, 2018 | 99 | 2018 |
| Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis MT Reetz, D Kahakeaw, J Sanchis Molecular BioSystems 5 (2), 115-122, 2009 | 96 | 2009 |
| Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics CG Acevedo-Rocha, A Li, L D’Amore, S Hoebenreich, J Sanchis, ... Nature Communications 12 (1), 1621, 2021 | 93 | 2021 |
| Many pathways in laboratory evolution can lead to improved enzymes: how to escape from local minima Y Gumulya, J Sanchis, MT Reetz ChemBioChem 13 (7), 1060-1066, 2012 | 84 | 2012 |
| Extreme synergistic mutational effects in the directed evolution of a Baeyer–Villiger monooxygenase as catalyst for asymmetric sulfoxidation ZG Zhang, R Lonsdale, J Sanchis, MT Reetz Journal of the American Chemical Society 136 (49), 17262-17272, 2014 | 74 | 2014 |
| Triblock copolymer nanovesicles for pH-responsive targeted delivery and controlled release of siRNA to cancer cells E Gallon, T Matini, L Sasso, G Mantovani, A Arminan de Benito, J Sanchis, ... Biomacromolecules 16 (7), 1924-1937, 2015 | 63 | 2015 |
| Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm X Feng, J Sanchis, MT Reetz, H Rabitz Chemistry–A European Journal 18 (18), 5646-5654, 2012 | 63 | 2012 |
| Complex multiblock bottle-brush architectures by RAFT polymerization A Kerr, M Hartlieb, J Sanchis, T Smith, S Perrier Chemical Communications 53 (87), 11901-11904, 2017 | 61 | 2017 |
| Creation of an amino acid network of structurally coupled residues in the directed evolution of a thermostable enzyme MT Reetz, P Soni, JP Acevedo, J Sanchis Angewandte Chemie International Edition 48 (44), 8268-8272, 2009 | 61 | 2009 |
| Cyclic peptide-poly (HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution SC Larnaudie, J Sanchis, TH Nguyen, R Peltier, S Catrouillet, JC Brendel, ... Biomaterials 178, 570-582, 2018 | 54 | 2018 |
| Synthesis and characterization of variable conformation pH responsive block co-polymers for nucleic acid delivery and targeted cell entry T Matini, N Francini, A Battocchio, SG Spain, G Mantovani, MJ Vicent, ... Polymer Chemistry 5 (5), 1626-1636, 2014 | 51 | 2014 |
| Conformationally regulated fluorescent sensors. Study of the selectivity in Zn2+ versus Cd2+ sensing AM Costero, S Gil, J Sanchis, S Peransı́, V Sanz, JAG Williams Tetrahedron 60 (30), 6327-6334, 2004 | 51 | 2004 |
| Secondary self‐assembly of supramolecular nanotubes into tubisomes and their activity on cells JC Brendel, J Sanchis, S Catrouillet, E Czuba, MZ Chen, BM Long, ... Angewandte Chemie International Edition 57 (51), 16678-16682, 2018 | 44 | 2018 |