A communal catalogue reveals Earth’s multiscale microbial diversity LR Thompson, JG Sanders, D McDonald, A Amir, J Ladau, KJ Locey, ... Nature 551 (7681), 457-463, 2017 | 2521 | 2017 |
Tissue-specific transcriptional regulation has diverged significantly between human and mouse DT Odom, RD Dowell, ES Jacobsen, W Gordon, TW Danford, ... Nature genetics 39 (6), 730-732, 2007 | 644 | 2007 |
The distributed annotation system RD Dowell, RM Jokerst, A Day, SR Eddy, L Stein BMC bioinformatics 2, 1-7, 2001 | 544 | 2001 |
Polyploidy can drive rapid adaptation in yeast AM Selmecki, YE Maruvka, PA Richmond, M Guillet, N Shoresh, ... Nature 519 (7543), 349-352, 2015 | 490 | 2015 |
Genotype to phenotype: a complex problem RD Dowell, O Ryan, A Jansen, D Cheung, S Agarwala, T Danford, ... Science 328 (5977), 469-469, 2010 | 480 | 2010 |
HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia MD Galbraith, MA Allen, CL Bensard, X Wang, MK Schwinn, B Qin, ... Cell 153 (6), 1327-1339, 2013 | 396 | 2013 |
Evaluation of several lightweight stochastic context-free grammars for RNA secondary structure prediction RD Dowell, SR Eddy BMC bioinformatics 5, 1-14, 2004 | 374 | 2004 |
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms MA Allen, Z Andrysik, VL Dengler, HS Mellert, A Guarnieri, JA Freeman, ... Elife 3, e02200, 2014 | 280 | 2014 |
Core transcriptional regulatory circuitry in human hepatocytes DT Odom, RD Dowell, ES Jacobsen, L Nekludova, PA Rolfe, TW Danford, ... Molecular systems biology 2 (1), 2006.0017, 2006 | 251 | 2006 |
Toggle involving cis-interfering noncoding RNAs controls variegated gene expression in yeast SL Bumgarner, RD Dowell, P Grisafi, DK Gifford, GR Fink Proceedings of the National Academy of Sciences 106 (43), 18321-18326, 2009 | 232 | 2009 |
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation S Cuartero, FD Weiss, G Dharmalingam, Y Guo, E Ing-Simmons, ... Nature immunology 19 (9), 932-941, 2018 | 207 | 2018 |
Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints RD Dowell, SR Eddy BMC bioinformatics 7, 1-18, 2006 | 172 | 2006 |
Just 2% of SARS-CoV-2− positive individuals carry 90% of the virus circulating in communities Q Yang, TK Saldi, PK Gonzales, E Lasda, CJ Decker, KL Tat, MR Fink, ... Proceedings of the National Academy of Sciences 118 (21), e2104547118, 2021 | 170 | 2021 |
Human TFIIH kinase CDK7 regulates transcription-associated chromatin modifications CC Ebmeier, B Erickson, BL Allen, MA Allen, H Kim, N Fong, JR Jacobsen, ... Cell reports 20 (5), 1173-1186, 2017 | 152 | 2017 |
Identification of mediator kinase substrates in human cells using cortistatin A and quantitative phosphoproteomics ZC Poss, CC Ebmeier, AT Odell, A Tangpeerachaikul, T Lee, HE Pelish, ... Cell reports 15 (2), 436-450, 2016 | 152 | 2016 |
Foxc1 reinforces quiescence in self-renewing hair follicle stem cells L Wang, JA Siegenthaler, RD Dowell, R Yi Science 351 (6273), 613-617, 2016 | 145 | 2016 |
Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts CJ Walker, C Crocini, D Ramirez, AR Killaars, JC Grim, BA Aguado, ... Nature biomedical engineering 5 (12), 1485-1499, 2021 | 138 | 2021 |
Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic EK Pugach, PA Richmond, JG Azofeifa, RD Dowell, LA Leinwand Journal of molecular and cellular cardiology 86, 54-61, 2015 | 133 | 2015 |
Enhancer RNA profiling predicts transcription factor activity JG Azofeifa, MA Allen, JR Hendrix, JD Rubin, RD Dowell Genome research 28 (3), 334-344, 2018 | 114 | 2018 |
High-resolution computational models of genome binding events Y Qi, A Rolfe, KD MacIsaac, GK Gerber, D Pokholok, J Zeitlinger, ... Nature biotechnology 24 (8), 963-970, 2006 | 107 | 2006 |