Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells KKY Cheng, KSL Lam, Y Wang, Y Huang, D Carling, D Wu, C Wong, A Xu Diabetes 56 (5), 1387-1394, 2007 | 417 | 2007 |
Vascular effects of adiponectin: molecular mechanisms and potential therapeutic intervention W Zhu, KKY Cheng, PM Vanhoutte, KSL Lam, A Xu Clinical Science 114 (5), 361-374, 2008 | 385 | 2008 |
Cross‐talk between adipose tissue and vasculature: role of adiponectin FYL Li, KKY Cheng, KSL Lam, PM Vanhoutte, A Xu Acta physiologica 203 (1), 167-180, 2011 | 193 | 2011 |
Chronic adiponectin deficiency leads to Alzheimer’s disease-like cognitive impairments and pathologies through AMPK inactivation and cerebral insulin resistance in aged mice RCL Ng, OY Cheng, M Jian, JSC Kwan, PWL Ho, KKY Cheng, ... Molecular neurodegeneration 11, 1-16, 2016 | 170 | 2016 |
Adiponectin is protective against oxidative stress induced cytotoxicity in amyloid-beta neurotoxicity KH Chan, KSL Lam, OY Cheng, JSC Kwan, PWL Ho, KKY Cheng, ... PloS one 7 (12), e52354, 2012 | 168 | 2012 |
APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice KKY Cheng, MA Iglesias, KSL Lam, Y Wang, G Sweeney, W Zhu, ... Cell Metabolism 9 (5), 417-427, 2009 | 161 | 2009 |
Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway J Chang, Y Li, Y Huang, KSL Lam, RLC Hoo, WT Wong, KKY Cheng, ... Diabetes 59 (11), 2949-2959, 2010 | 151 | 2010 |
Signaling mechanisms underlying the insulin-sensitizing effects of adiponectin KKY Cheng, KSL Lam, B Wang, A Xu Best practice & research Clinical endocrinology & metabolism 28 (1), 3-13, 2014 | 145 | 2014 |
Suppression of the Raf/MEK/ERK signaling cascade and inhibition of angiogenesis by the carboxyl terminus of angiopoietin-like protein 4 YH Yang, Y Wang, KSL Lam, MH Yau, KKY Cheng, J Zhang, W Zhu, ... Arteriosclerosis, thrombosis, and vascular biology 28 (5), 835-840, 2008 | 137 | 2008 |
The role of adipose tissue senescence in obesity-and ageing-related metabolic disorders Z Liu, KKL Wu, X Jiang, A Xu, KKY Cheng Clinical science 134 (2), 315-330, 2020 | 132 | 2020 |
Polymorphisms of the gene encoding adiponectin and glycaemic outcome of Chinese subjects with impaired glucose tolerance: a 5-year follow-up study AWK Tso, PC Sham, NMS Wat, A Xu, BMY Cheung, R Rong, CHY Fong, ... Diabetologia 49, 1806-1815, 2006 | 96 | 2006 |
The novel perspectives of adipokines on brain health TH Lee, KK Cheng, RL Hoo, PM Siu, S Yau International journal of molecular sciences 20 (22), 5638, 2019 | 93 | 2019 |
PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance M Cao, Z Mao, C Kam, N Xiao, X Cao, C Shen, KKY Cheng, A Xu, KM Lee, ... PLoS biology 11 (4), e1001541, 2013 | 90 | 2013 |
APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice KKY Cheng, KSL Lam, D Wu, Y Wang, G Sweeney, RLC Hoo, J Zhang, ... Proceedings of the National Academy of Sciences 109 (23), 8919-8924, 2012 | 88 | 2012 |
SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding H Jang, GY Lee, CP Selby, G Lee, YG Jeon, JH Lee, KKY Cheng, ... Nature communications 7 (1), 12180, 2016 | 87 | 2016 |
Sarcopenia and mortality in cancer: A meta-analysis PCM Au, HL Li, GKY Lee, GHY Li, M Chan, BMY Cheung, ICK Wong, ... Osteoporosis and sarcopenia 7, S28-S33, 2021 | 85 | 2021 |
Hypothalamic AMPK as a mediator of hormonal regulation of energy balance B Wang, KKY Cheng International Journal of Molecular Sciences 19 (11), 3552, 2018 | 84 | 2018 |
APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice Y Wang, KKY Cheng, KSL Lam, D Wu, Y Wang, Y Huang, PM Vanhoutte, ... Diabetes 60 (11), 3044-3054, 2011 | 84 | 2011 |
Safety and antitumor activity of GD2-Specific 4SCAR-T cells in patients with glioblastoma Z Liu, J Zhou, X Yang, Y Liu, C Zou, W Lv, C Chen, KK Cheng, T Chen, ... Molecular cancer 22 (1), 3, 2023 | 77 | 2023 |
NLRP3 inflammasome activation in adipose tissues and its implications on metabolic diseases KKL Wu, SWM Cheung, KKY Cheng International Journal of Molecular Sciences 21 (11), 4184, 2020 | 70 | 2020 |