Human bone marrow organoids for disease modeling, discovery, and validation of therapeutic targets in hematologic malignancies AO Khan, A Rodriguez-Romera, JS Reyat, AA Olijnik, M Colombo, ... Cancer Discovery 13 (2), 364-385, 2023 | 87 | 2023 |
Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface KA Khan, AJ Naylor, A Khan, PJ Noy, M Mambretti, P Lodhia, J Athwal, ... Oncogene 36 (44), 6097-6108, 2017 | 81 | 2017 |
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2 PLR Nicolson, SH Nock, J Hinds, L Garcia-Quintanilla, CW Smith, ... Haematologica 106 (1), 208, 2020 | 67 | 2020 |
Protein Corona Modulates Uptake and Toxicity of Nanoceria via Clathrin-Mediated Endocytosis J Mazzolini, RJM Weber, HS Chen, A Khan, E Guggenheim, RK Shaw, ... The Biological Bulletin 231 (1), 40-60, 2016 | 66 | 2016 |
Topological data analysis quantifies biological nano-structure from single molecule localization microscopy JA Pike, AO Khan, C Pallini, SG Thomas, M Mund, J Ries, NS Poulter, ... Bioinformatics 36 (5), 1614-1621, 2020 | 64 | 2020 |
Neutrophil extracellular traps and inflammasomes cooperatively promote venous thrombosis in mice J Campos, T Ponomaryov, A De Prendergast, K Whitworth, CW Smith, ... Blood Advances 5 (9), 2319-2324, 2021 | 56 | 2021 |
CRISPR-Cas9 mediated labelling allows for single molecule imaging and resolution AO Khan, VA Simms, JA Pike, SG Thomas, NV Morgan Scientific reports 7 (1), 8450, 2017 | 54 | 2017 |
Comparison of confocal and super-resolution reflectance imaging of metal oxide nanoparticles EJ Guggenheim, A Khan, J Pike, L Chang, I Lynch, JZ Rappoport PloS one 11 (10), e0159980, 2016 | 53 | 2016 |
Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines I Hansjosten, J Rapp, L Reiner, R Vatter, S Fritsch-Decker, R Peravali, ... Archives of toxicology 92, 633-649, 2018 | 51 | 2018 |
S100A8/A9 drives the formation of procoagulant platelets through GPIbα M Colicchia, WC Schrottmaier, G Perrella, JS Reyat, J Begum, A Slater, ... Blood, The Journal of the American Society of Hematology 140 (24), 2626-2643, 2022 | 49 | 2022 |
TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice CW Smith, Z Raslan, L Parfitt, AO Khan, P Patel, YA Senis, A Mazharian Blood advances 2 (16), 2072-2078, 2018 | 49 | 2018 |
Preferential uptake of SARS-CoV-2 by pericytes potentiates vascular damage and permeability in an organoid model of the microvasculature AO Khan, JS Reyat, H Hill, JH Bourne, M Colicchia, ML Newby, JD Allen, ... Cardiovascular research 118 (15), 3085-3096, 2022 | 31 | 2022 |
An adaptable analysis workflow for characterization of platelet spreading and morphology JA Pike, VA Simms, CW Smith, NV Morgan, AO Khan, NS Poulter, ... Platelets 32 (1), 54-58, 2021 | 31 | 2021 |
Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in AO Khan, CW White, JA Pike, J Yule, A Slater, SJ Hill, NS Poulter, ... Scientific reports 9 (1), 14219, 2019 | 28 | 2019 |
Post-translational polymodification of b1-tubulin regulates motor protein localization in platelet production and function AO Khan, A Slater, A Maclachlan, PLR Nicolson, JA Pike, JS Reyat, ... Haematologica 107 (1), 243, 2020 | 27 | 2020 |
High-throughput platelet spreading analysis: a tool for the diagnosis of platelet-based bleeding disorders. AO Khan, A Maclachlan, GC Lowe, PLR Nicolson, RA Ghaithi, ... haematologica 105 (3), e124, 2020 | 24 | 2020 |
Adverse outcome in COVID-19 is associated with an aggravating hypo-responsive platelet phenotype WC Schrottmaier, A Pirabe, D Pereyra, S Heber, H Hackl, ... Frontiers in cardiovascular medicine 8, 795624, 2021 | 23 | 2021 |
Surface Chemistry-Dependent Evolution of the Nanomaterial Corona on TiO2 Nanomaterials Following Uptake and Sub-Cellular Localization JZRIL Abdullah O. Khan, Alessandro Di Maio, Emily J. Guggenheim, Andrew J ... Nanomaterials 10 (3), 401, 2020 | 23 | 2020 |
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation O Krysko, JH Bourne, E Kondakova, EA Galova, K Whitworth, ML Newby, ... Frontiers in immunology 13, 968981, 2022 | 22 | 2022 |
Role of the novel endoribonuclease SLFN14 and its disease-causing mutations in ribosomal degradation SJ Fletcher, VP Pisareva, AO Khan, A Tcherepanov, NV Morgan, ... RNA 24 (7), 939-949, 2018 | 22 | 2018 |