SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ... Cell metabolism 15 (5), 675-690, 2012 | 1727 | 2012 |
Metformin improves healthspan and lifespan in mice A Martin-Montalvo, EM Mercken, SJ Mitchell, HH Palacios, PL Mote, ... Nature communications 4 (1), 2192, 2013 | 1536 | 2013 |
Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans J Guevara-Aguirre, P Balasubramanian, M Guevara-Aguirre, M Wei, ... Science translational medicine 3 (70), 70ra13-70ra13, 2011 | 878 | 2011 |
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy C Lee, L Raffaghello, S Brandhorst, FM Safdie, G Bianchi, ... Science translational medicine 4 (124), 124ra27-124ra27, 2012 | 865 | 2012 |
The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance C Lee, J Zeng, BG Drew, T Sallam, A Martin-Montalvo, J Wan, SJ Kim, ... Cell metabolism 21 (3), 443-454, 2015 | 668 | 2015 |
The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet SJ Mitchell, A Martin-Montalvo, EM Mercken, HH Palacios, TM Ward, ... Cell reports 6 (5), 836-843, 2014 | 452 | 2014 |
Fasting-mimicking diet reduces HO-1 to promote T cell-mediated tumor cytotoxicity S Di Biase, C Lee, S Brandhorst, B Manes, R Buono, CW Cheng, ... Cancer cell 30 (1), 136-146, 2016 | 400 | 2016 |
Therapeutic potential of mesenchymal stem cells for cancer therapy A Hmadcha, A Martin-Montalvo, BR Gauthier, B Soria, V Capilla-Gonzalez Frontiers in bioengineering and biotechnology 8, 43, 2020 | 351 | 2020 |
SRT1720 improves survival and healthspan of obese mice RK Minor, JA Baur, AP Gomes, TM Ward, A Csiszar, EM Mercken, ... Scientific reports 1 (1), 1-11, 2011 | 340 | 2011 |
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet Y Jimenez-Gomez, JA Mattison, KJ Pearson, A Martin-Montalvo, ... Cell metabolism 18 (4), 533-545, 2013 | 292 | 2013 |
SRT 2104 extends survival of male mice on a standard diet and preserves bone and muscle mass EM Mercken, SJ Mitchell, A Martin‐Montalvo, RK Minor, M Almeida, ... Aging cell 13 (5), 787-796, 2014 | 263 | 2014 |
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice AL Birkenfeld, HY Lee, F Guebre-Egziabher, TC Alves, MJ Jurczak, ... Cell metabolism 14 (2), 184-195, 2011 | 214 | 2011 |
Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence N Noren Hooten, A Martin‐Montalvo, DF Dluzen, Y Zhang, M Bernier, ... Aging cell 15 (3), 572-581, 2016 | 193 | 2016 |
Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells C Lee-Chang, M Bodogai, A Martin-Montalvo, K Wejksza, M Sanghvi, ... The Journal of Immunology 191 (8), 4141-4151, 2013 | 166 | 2013 |
NRF2, cancer and calorie restriction A Martín-Montalvo, JM Villalba, P Navas, R De Cabo Oncogene 30 (5), 505-520, 2011 | 158 | 2011 |
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein M Bernier, RK Paul, A Martin-Montalvo, M Scheibye-Knudsen, S Song, ... Journal of Biological Chemistry 286 (22), 19270-19279, 2011 | 155 | 2011 |
Thyroid hormones in diabetes, cancer, and aging BR Gauthier, A Sola‐García, MÁ Cáliz‐Molina, PI Lorenzo, ... Aging cell 19 (11), e13260, 2020 | 120 | 2020 |
Mitochondrial metabolic reprogramming induced by calorie restriction A Martin-Montalvo, R de Cabo Antioxidants & redox signaling 19 (3), 310-320, 2013 | 114 | 2013 |
Cytochrome b5 reductase and the control of lipid metabolism and healthspan A Martin-Montalvo, Y Sun, A Diaz-Ruiz, A Ali, V Gutierrez, HH Palacios, ... npj Aging and Mechanisms of Disease 2 (1), 1-12, 2016 | 84 | 2016 |
Intergenerational transmission of the positive effects of physical exercise on brain and cognition KR McGreevy, P Tezanos, I Ferreiro-Villar, A Pallé, M Moreno-Serrano, ... Proceedings of the National Academy of Sciences 116 (20), 10103-10112, 2019 | 63 | 2019 |