The association between sterilizing activity and drug distribution into tuberculosis lesions B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ... Nature medicine 21 (10), 1223-1227, 2015 | 507 | 2015 |
Inflammatory signaling in human tuberculosis granulomas is spatially organized MJ Marakalala, RM Raju, K Sharma, YJ Zhang, EA Eugenin, B Prideaux, ... Nature medicine 22 (5), 531-538, 2016 | 329 | 2016 |
Mass spectrometry imaging for drug distribution studies B Prideaux, M Stoeckli Journal of proteomics 75 (16), 4999-5013, 2012 | 329 | 2012 |
High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions B Prideaux, V Dartois, D Staab, DM Weiner, A Goh, LE Via, CE Barry III, ... Analytical chemistry 83 (6), 2112-2118, 2011 | 292 | 2011 |
Autoradiography, MALDI-MS, and SIMS-MS imaging in pharmaceutical discovery and development EG Solon, A Schweitzer, M Stoeckli, B Prideaux The AAPS journal 12, 11-26, 2010 | 286 | 2010 |
Fatty acid synthesis is required for breast cancer brain metastasis GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... Nature cancer 2 (4), 414-428, 2021 | 237 | 2021 |
Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice SM Irwin, B Prideaux, ER Lyon, MD Zimmerman, EJ Brooks, CA Schrupp, ... ACS infectious diseases 2 (4), 251-267, 2016 | 149 | 2016 |
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development T Beites, K O’Brien, D Tiwari, CA Engelhart, S Walters, J Andrews, ... Nature communications 10 (1), 4970, 2019 | 117 | 2019 |
Statin adjunctive therapy shortens the duration of TB treatment in mice NK Dutta, N Bruiners, ML Pinn, MD Zimmerman, B Prideaux, V Dartois, ... Journal of Antimicrobial Chemotherapy 71 (6), 1570-1577, 2016 | 116 | 2016 |
Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific V Guerrini, B Prideaux, L Blanc, N Bruiners, R Arrigucci, S Singh, ... PLoS pathogens 14 (8), e1007223, 2018 | 104 | 2018 |
Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model Y Zhao, B Prideaux, Y Nagasaki, MH Lee, PY Chen, L Blanc, H Ho, ... Antimicrobial agents and chemotherapy 61 (10), 10.1128/aac. 01009-17, 2017 | 96 | 2017 |
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives LE Via, R Savic, DM Weiner, MD Zimmerman, B Prideaux, SM Irwin, ... ACS infectious diseases 1 (5), 203-214, 2015 | 88 | 2015 |
Tumor drug penetration measurements could be the neglected piece of the personalized cancer treatment puzzle IH Bartelink, EF Jones, SK Shahidi‐Latham, PRE Lee, Y Zheng, P Vicini, ... Clinical Pharmacology & Therapeutics 106 (1), 148-163, 2019 | 84 | 2019 |
Visualization of mycobacterial biomarkers and tuberculosis drugs in infected tissue by MALDI-MS imaging L Blanc, A Lenaerts, V Dartois, B Prideaux Analytical Chemistry 90 (10), 6275-6282, 2018 | 83 | 2018 |
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00924-17, 2017 | 83 | 2017 |
Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling B Prideaux, MS ElNaggar, M Zimmerman, JM Wiseman, X Li, V Dartois International journal of mass spectrometry 377, 699-708, 2015 | 80 | 2015 |
Tunneling nanotubes, TNT, communicate glioblastoma with surrounding non-tumor astrocytes to adapt them to hypoxic and metabolic tumor conditions S Valdebenito, S Malik, R Luu, O Loudig, M Mitchell, G Okafo, K Bhat, ... Scientific reports 11 (1), 14556, 2021 | 72 | 2021 |
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach E Pienaar, J Sarathy, B Prideaux, J Dietzold, V Dartois, DE Kirschner, ... PLoS computational biology 13 (8), e1005650, 2017 | 68 | 2017 |
Mass spectrometry imaging to detect lipid biomarkers and disease signatures in cancer M Holzlechner, E Eugenin, B Prideaux Cancer reports 2 (6), e1229, 2019 | 66 | 2019 |
Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations J Sarathy, L Blanc, N Alvarez-Cabrera, P O’brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 63 (5), 10.1128/aac. 02516-18, 2019 | 64 | 2019 |