REDD1 enhances protein phosphatase 2A–mediated dephosphorylation of Akt to repress mTORC1 signaling MD Dennis, CS Coleman, A Berg, LS Jefferson, SR Kimball Science signaling 7 (335), ra68-ra68, 2014 | 168 | 2014 |
Role of p70S6K1-mediated phosphorylation of eIF4B and PDCD4 proteins in the regulation of protein synthesis MD Dennis, LS Jefferson, SR Kimball Journal of Biological Chemistry 287 (51), 42890-42899, 2012 | 158 | 2012 |
The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb AR Kelleher, SR Kimball, MD Dennis, RJ Schilder, LS Jefferson American Journal of Physiology-Endocrinology And Metabolism 304 (2), E229-E236, 2013 | 129 | 2013 |
Mechanisms involved in the coordinate regulation of mTORC1 by insulin and amino acids MD Dennis, JI Baum, SR Kimball, LS Jefferson Journal of Biological Chemistry 286 (10), 8287-8296, 2011 | 127 | 2011 |
Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation SR Kimball, BS Gordon, JE Moyer, MD Dennis, LS Jefferson Cellular signalling 28 (8), 896-906, 2016 | 108 | 2016 |
Phosphorylation by CK2 enhances the rapid light-induced degradation of phytochrome interacting factor 1 in Arabidopsis Q Bu, L Zhu, MD Dennis, L Yu, SX Lu, MD Person, EM Tobin, ... Journal of Biological Chemistry 286 (14), 12066-12074, 2011 | 108 | 2011 |
Regulated in DNA damage and development 1 (REDD1) promotes cell survival during serum deprivation by sustaining repression of signaling through the mechanistic target of … MD Dennis, NK McGhee, LS Jefferson, SR Kimball Cellular signalling 25 (12), 2709-2716, 2013 | 102 | 2013 |
Phosphorylation of plant translation initiation factors by CK2 enhances the in vitro interaction of multifactor complex components MD Dennis, MD Person, KS Browning Journal of Biological Chemistry 284 (31), 20615-20628, 2009 | 84 | 2009 |
Evidence for variation in the optimal translation initiation complex: plant eIF4B, eIF4F, and eIF (iso) 4F differentially promote translation of mRNAs LK Mayberry, ML Allen, MD Dennis, KS Browning Plant physiology 150 (4), 1844-1854, 2009 | 79 | 2009 |
Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents MD Dennis, SR Kimball, PE Fort, LS Jefferson Journal of Biological Chemistry 290 (6), 3865-3874, 2015 | 66 | 2015 |
Differential phosphorylation of plant translation initiation factors by Arabidopsis thaliana CK2 holoenzymes MD Dennis, KS Browning Journal of Biological Chemistry 284 (31), 20602-20614, 2009 | 65 | 2009 |
The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation WP Miller, S Sunilkumar, JF Giordano, AL Toro, AJ Barber, MD Dennis Journal of Biological Chemistry 295 (21), 7350-7361, 2020 | 62 | 2020 |
RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells BS Gordon, AA Kazi, CS Coleman, MD Dennis, V Chau, LS Jefferson, ... Cellular signalling 26 (3), 461-467, 2014 | 62 | 2014 |
ATF4-mediated upregulation of REDD1 and Sestrin2 suppresses mTORC1 activity during prolonged leucine deprivation D Xu, W Dai, L Kutzler, HA Lacko, LS Jefferson, MD Dennis, SR Kimball The Journal of nutrition 150 (5), 1022-1030, 2020 | 52 | 2020 |
mTORC1 and JNK coordinate phosphorylation of the p70S6K1 autoinhibitory domain in skeletal muscle following functional overloading TD Martin, MD Dennis, BS Gordon, SR Kimball, LS Jefferson American Journal of Physiology-Endocrinology and Metabolism 306 (12), E1397 …, 2014 | 51 | 2014 |
Expression and purification of recombinant wheat translation initiation factors eIF1, eIF1A, eIF4A, eIF4B, eIF4F, eIF (iso) 4F, and eIF5 LK Mayberry, MD Dennis, ML Allen, KR Nitka, PA Murphy, L Campbell, ... Methods in enzymology 430, 397-408, 2007 | 50 | 2007 |
Deletion of the Akt/mTORC1 repressor REDD1 prevents visual dysfunction in a rodent model of type 1 diabetes WP Miller, C Yang, ML Mihailescu, JA Moore, W Dai, AJ Barber, ... Diabetes 67 (1), 110-119, 2018 | 49 | 2018 |
REDD1 activates a ROS-generating feedback loop in the retina of diabetic mice WP Miller, AL Toro, AJ Barber, MD Dennis Investigative ophthalmology & visual science 60 (6), 2369-2379, 2019 | 44 | 2019 |
Hyperglycemia mediates a shift from cap-dependent to cap-independent translation via a 4E-BP1–dependent mechanism MD Dennis, JS Shenberger, BA Stanley, SR Kimball, LS Jefferson Diabetes 62 (7), 2204-2214, 2013 | 44 | 2013 |
Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor MD Dennis, SR Kimball, LS Jefferson Journal of Biological Chemistry 288 (1), 10-19, 2013 | 39 | 2013 |