Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity Z Adhireksan, GE Davey, P Campomanes, M Groessl, CM Clavel, H Yu, ... Nature communications 5 (1), 3462, 2014 | 331 | 2014 |
A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core B Wu, MS Ong, M Groessl, Z Adhireksan, CG Hartinger, PJ Dyson, ... Chemistry–A European Journal 13 (17), 3562-3566, 2011 | 195 | 2011 |
Novel metal (II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents SM Meier, M Hanif, Z Adhireksan, V Pichler, M Novak, E Jirkovsky, ... Chemical Science 4 (4), 1837-1846, 2013 | 146 | 2013 |
Allosteric cross-talk in chromatin can mediate drug-drug synergy Z Adhireksan, G Palermo, T Riedel, Z Ma, R Muhammad, U Rothlisberger, ... Nature communications 8 (1), 14860, 2017 | 72 | 2017 |
Near-atomic resolution structures of interdigitated nucleosome fibres Z Adhireksan, D Sharma, PL Lee, CA Davey Nature communications 11 (1), 4747, 2020 | 47 | 2020 |
Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation GE Davey, Z Adhireksan, Z Ma, T Riedel, D Sharma, S Padavattan, ... Nature communications 8 (1), 1575, 2017 | 41 | 2017 |
An Organometallic Compound which Exhibits a DNA Topology‐Dependent One‐Stranded Intercalation Mode Z Ma, G Palermo, Z Adhireksan, BS Murray, T Von Erlach, PJ Dyson, ... Angewandte Chemie 128 (26), 7567-7570, 2016 | 19 | 2016 |
Functionalization of Ruthenium(II)(η6‐p‐cymene)(3‐hydroxy‐2‐pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies M Hanif, SM Meier, Z Adhireksan, H Henke, S Martic, S Movassaghi, ... ChemPlusChem 82 (6), 841-847, 2017 | 16 | 2017 |
Crosslinking allosteric sites on the nucleosome LK Batchelor, L De Falco, T von Erlach, D Sharma, Z Adhireksan, ... Angewandte Chemie 131 (44), 15807-15811, 2019 | 10 | 2019 |
Engineering nucleosomes for generating diverse chromatin assemblies Z Adhireksan, D Sharma, PL Lee, Q Bao, S Padavattan, WK Shum, ... Nucleic Acids Research 49 (9), e52-e52, 2021 | 8 | 2021 |
An organometallic compound displays a unique one-stranded intercalation mode that is DNA topology-dependent Z Ma, G Palermo, Z Adhireksan, BS Murray, T Von Erlach, PJ Dyson, ... Angew Chem Int Ed 128, 7441-7444, 2016 | 6 | 2016 |
Back Cover: Functionalization of Ruthenium(II)(η6‐p‐cymene)(3‐hydroxy‐2‐pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies … M Hanif, SM Meier, Z Adhireksan, H Henke, S Martic, S Movassaghi, ... ChemPlusChem 82 (6), 2017 | | 2017 |
Exploring the therapeutic landscape of chromatin via integrative computational modeling: An allosteric regulation from transition metal agents G Palermo, Z Adhireksan, T Riedel, Z Ma, R Muhammad, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Molecular simulations disclose a novel mode of one-stranded intercalation in nucleosomes that is DNA topology dependent G Palermo, Z Ma, Z Adhireksan, BS Murray, T von Erlach, PJ Dyson, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Characterizing the nucleosome site selectivity, adduct structures and impact on chromatin for a variety of metal-based anticancer compounds and structural studies of nucleosome … Z Adhireksan | | 2016 |
Targeting Epigenetic Vulnerabilities of Cancer Cells by Exploiting Chromatin Structure and Chemistry Z Adhireksan, GE Davey, Z Ma, G Palermo, T Riedel, BS Murray, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 72, S204-S205, 2016 | | 2016 |
X-ray Crystallographic Analysis of the Chromatosome S Padavattan, Z Adhireksan, Q Bao, CA Davey ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 72, S213-S213, 2016 | | 2016 |
X-Ray Crystal Structure of a Chromatosome CA Davey, Z Adhireksan, Q Bao, S Padavattan ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 72, S53-S53, 2016 | | 2016 |
Organometallic anticancer agents S Moon, S Wiezorek, K Tong, CH Lin, SM Meier, M Hanif, S Jamieson, ... Journal of Biological Inorganic Chemistry 19, S730-S730, 2014 | | 2014 |
Organometallic Anticancer Agents: Bioactive Ligand Systems as Key Elements Determining the Biological Properties C Hartinger, S Meier, A Kurzwernhart, M Babak, W Kandioller, E Balsano, ... JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 19, S189-S189, 2014 | | 2014 |