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Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations Y Wang, J Guo, G Ni, J Yang, P Visscher, L Yengo Nature Communications 11, 2020 | 314 | 2020 |
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ... Cell Genomics 2 (10), 2022 | 283 | 2022 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 183 | 2021 |
Challenges and opportunities for developing more generalizable polygenic risk scores Y Wang, K Tsuo, M Kanai, BM Neale, AR Martin Annual review of biomedical data science 5 (1), 293-320, 2022 | 118 | 2022 |
Principles and methods for transferring polygenic risk scores across global populations L Kachuri, N Chatterjee, J Hirbo, DJ Schaid, I Martin, IJ Kullo, EE Kenny, ... Nature Reviews Genetics 25 (1), 8-25, 2024 | 100 | 2024 |
Genetic polymorphisms and mutation rates of 27 Y-chromosomal STRs in a Han population from Guangdong Province, Southern China Y Wang, Y Zhang, C Zhang, R Li, Y Yang, X Ou, D Tong, H Sun Forensic Science International: Genetics 21, 5-9, 2016 | 99 | 2016 |
Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases Y Yang, H Musco, S Simpson-Yap, Z Zhu, Y Wang, X Lin, J Zhang, ... Nature communications 12 (1), 5641, 2021 | 89 | 2021 |
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts Y Wang, S Namba, E Lopera, S Kerminen, K Tsuo, K Läll, M Kanai, ... Cell Genomics 3 (1), 2023 | 82 | 2023 |
Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity K Tsuo, W Zhou, Y Wang, M Kanai, S Namba, R Gupta, L Majara, ... Cell genomics 2 (12), 2022 | 71 | 2022 |
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution M Kanai, R Elzur, W Zhou, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, ... Cell genomics 2 (12), 2022 | 65 | 2022 |
Low and differential polygenic score generalizability among African populations due largely to genetic diversity L Majara, A Kalungi, N Koen, K Tsuo, Y Wang, R Gupta, LL Nkambule, ... Human Genetics and Genomics Advances 4 (2), 2023 | 54* | 2023 |
Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries Z Zheng, S Liu, J Sidorenko, Y Wang, T Lin, L Yengo, P Turley, A Ani, ... Nature Genetics, 1-11, 2024 | 42 | 2024 |
Quantifying genetic heterogeneity between continental populations for human height and body mass index J Guo, A Bakshi, Y Wang, L Jiang, L Yengo, ME Goddard, PM Visscher, ... Scientific reports 11 (1), 5240, 2021 | 42 | 2021 |
Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics JJ Partanen, P Häppölä, W Zhou, AA Lehisto, M Ainola, E Sutinen, ... Cell genomics 2 (10), 2022 | 39 | 2022 |
Haplotype analysis of the polymorphic 40 Y-STR markers in Chinese populations X Ou, Y Wang, C Liu, D Yang, C Zhang, S Deng, H Sun Forensic Science International: Genetics 19, 255-262, 2015 | 38 | 2015 |
Swa object detection H Zhang, Y Wang, F Dayoub, N Sünderhauf arXiv preprint arXiv:2012.12645, 2020 | 37 | 2020 |
Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects KJ Karczewski, R Gupta, M Kanai, W Lu, K Tsuo, Y Wang, RK Walters, ... MedRxiv, 2024.03. 13.24303864, 2024 | 33 | 2024 |
Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases B Truong, LE Hull, Y Ruan, QQ Huang, W Hornsby, H Martin, ... Cell Genomics 4 (4), 2024 | 29 | 2024 |
Best practices for multi-ancestry, meta-analytic transcriptome-wide association studies: lessons from the Global Biobank Meta-analysis Initiative A Bhattacharya, JB Hirbo, D Zhou, W Zhou, J Zheng, M Kanai, B Pasaniuc, ... Cell genomics 2 (10), 2022 | 29 | 2022 |