Fungal microbiota dysbiosis in IBD H Sokol, V Leducq, H Aschard, HP Pham, S Jegou, C Landman, D Cohen, ... Gut 66 (6), 1039-1048, 2017 | 1285 | 2017 |
Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 844 | 2021 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 540 | 2021 |
Effect of 17q21 variants and smoking exposure in early-onset asthma E Bouzigon, E Corda, H Aschard, MH Dizier, A Boland, J Bousquet, ... New England journal of medicine 359 (19), 1985-1994, 2008 | 515 | 2008 |
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels X Jiang, PF O’Reilly, H Aschard, YH Hsu, JB Richards, J Dupuis, ... Nature communications 9 (1), 260, 2018 | 437 | 2018 |
Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr F Privé, H Aschard, A Ziyatdinov, MGB Blum Bioinformatics 34 (16), 2781-2787, 2018 | 322 | 2018 |
Adjusting for heritable covariates can bias effect estimates in genome-wide association studies H Aschard, BJ Vilhjálmsson, AD Joshi, AL Price, P Kraft The American Journal of Human Genetics 96 (2), 329-339, 2015 | 322 | 2015 |
Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma JNC Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, ... Nature genetics 48 (2), 189-194, 2016 | 281 | 2016 |
Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort F Privé, H Aschard, S Carmi, L Folkersen, C Hoggart, PF O’Reilly, ... The American Journal of Human Genetics 109 (1), 12-23, 2022 | 257 | 2022 |
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges B Piasecka, D Duffy, A Urrutia, H Quach, E Patin, C Posseme, J Bergstedt, ... Proceedings of the National Academy of Sciences 115 (3), E488-E497, 2018 | 226 | 2018 |
Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies H Aschard, BJ Vilhjálmsson, N Greliche, PE Morange, DA Trégouët, ... The American Journal of Human Genetics 94 (5), 662-676, 2014 | 209 | 2014 |
Current challenges and new opportunities for gene-environment interaction studies of complex diseases K McAllister, LE Mechanic, C Amos, H Aschard, IA Blair, N Chatterjee, ... American journal of epidemiology 186 (7), 753-761, 2017 | 201 | 2017 |
A Comprehensive Analysis of In Vitro and In Vivo Genetic Fitness of Pseudomonas aeruginosa Using High-Throughput Sequencing of Transposon Libraries D Skurnik, D Roux, H Aschard, V Cattoir, D Yoder-Himes, S Lory, GB Pier PLoS pathogens 9 (9), e1003582, 2013 | 193 | 2013 |
Making the most of clumping and thresholding for polygenic scores F Privé, BJ Vilhjálmsson, H Aschard, MGB Blum The American journal of human genetics 105 (6), 1213-1221, 2019 | 189 | 2019 |
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ... Nature genetics 52 (1), 56-73, 2020 | 184 | 2020 |
Challenges and opportunities in genome-wide environmental interaction (GWEI) studies H Aschard, S Lutz, B Maus, EJ Duell, TE Fingerlin, N Chatterjee, P Kraft, ... Human genetics 131, 1591-1613, 2012 | 178 | 2012 |
Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function DB Hancock, MS Artigas, SA Gharib, A Henry, A Manichaikul, ... PLoS genetics 8 (12), e1003098, 2012 | 174 | 2012 |
Fitness cost of antibiotic susceptibility during bacterial infection D Roux, O Danilchanka, T Guillard, V Cattoir, H Aschard, Y Fu, ... Science translational medicine 7 (297), 297ra114-297ra114, 2015 | 168 | 2015 |
A large-scale multi-ancestry genome-wide study accounting for smoking behavior identifies multiple significant loci for blood pressure YJ Sung, TW Winkler, L de Las Fuentes, AR Bentley, MR Brown, AT Kraja, ... The American Journal of Human Genetics 102 (3), 375-400, 2018 | 166 | 2018 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 164 | 2022 |