Translational regulations in response to endoplasmic reticulum stress in cancers M Jaud, C Philippe, D Di Bella, W Tang, S Pyronnet, H Laurell, ... Cells 9 (3), 540, 2020 | 65 | 2020 |
PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress C Philippe, A Dubrac, C Quelen, A Desquesnes, L Van Den Berghe, ... Science signaling 9 (426), ra44-ra44, 2016 | 47 | 2016 |
ER stress and unfolded protein response in leukemia: friend, foe, or both? K Féral, M Jaud, C Philippe, D Di Bella, S Pyronnet, K Rouault-Pierre, ... Biomolecules 11 (2), 199, 2021 | 46 | 2021 |
Key contribution of eIF4H-mediated translational control in tumor promotion C Vaysse, C Philippe, Y Martineau, C Quelen, C Hieblot, C Renaud, ... Oncotarget 6 (37), 39924, 2015 | 45 | 2015 |
Hypoxia and ER stress promote Staufen1 expression through an alternative translation mechanism F Bonnet-Magnaval, C Philippe, L Van Den Berghe, H Prats, C Touriol, ... Biochemical and biophysical research communications 479 (2), 365-371, 2016 | 29 | 2016 |
The PERK branch of the unfolded protein response promotes DLL4 expression by activating an alternative translation mechanism M Jaud, C Philippe, L Van Den Berghe, C Ségura, L Mazzolini, ... Cancers 11 (2), 142, 2019 | 19 | 2019 |
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death K Woodley, LS Dillingh, G Giotopoulos, P Madrigal, KM Rattigan, ... Nature Communications 14 (1), 2132, 2023 | 17 | 2023 |
The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes N Berastegui, M Ainciburu, JP Romero, P Garcia-Olloqui, ... Nature Communications 13 (1), 7619, 2022 | 15 | 2022 |
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia SA Mian, C Philippe, E Maniati, P Protopapa, T Bergot, M Piganeau, ... Science translational medicine 15 (685), eabn5135, 2023 | 12 | 2023 |
Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment H Armes, F Bewicke‐Copley, A Rio‐Machin, D Di Bella, C Philippe, ... British Journal of Haematology 199 (5), 754-764, 2022 | 8 | 2022 |
Pivotal role of the endoplasmic reticulum stress-related XBP1s/miR-22/SIRT1 axis in acute myeloid leukemia apoptosis and response to chemotherapy C Philippe, M Jaud, K Féral, A Gay, L Van Den Berghe, M Farce, ... Leukemia 38 (8), 1764-1776, 2024 | 7 | 2024 |
Transcriptional regulation of HSCs in aging and MDS reveals DDIT3 as a potential driver of transformation N Berastegui, M Ainciburu, JP Romero, A Alfonso-Pierola, C Philippe, ... bioRxiv, 2021.09. 08.459384, 2021 | 4 | 2021 |
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation V Dembitz, H Lawson, R Burt, S Natani, C Philippe, SC James, S Atkinson, ... Leukemia 38 (11), 2395-2409, 2024 | 2 | 2024 |
The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts IY Choi, JP Ling, J Zhang, E Helmenstine, W Walter, P Tsakiroglou, ... Blood Advances 8 (15), 3961-3971, 2024 | 1 | 2024 |
SCD inhibition preferentially eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy V Dembitz, H Lawson, R Burt, C Philippe, SC James, S Atkinson, J Durko, ... bioRxiv, 2023.08. 02.551656, 2023 | 1 | 2023 |
Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia V Dembitz, H Lawson, C Philippe, RJ Burt, S James, ASM Magee, ... Blood 140 (Supplement 1), 3058-3060, 2022 | 1 | 2022 |
Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia K Woodley, LS Dillingh, G Giotopoulos, P Madrigal, K Tzelepis, C Philippe, ... Blood 138, 508, 2021 | 1 | 2021 |
A Comprehensive Pipeline to Assess the Efficiency of Human Erythropoiesis In Vitro and Ex Vivo C Philippe, S Burke, K Rouault-Pierre Journal of Visualized Experiments (JoVE), e67123, 2025 | | 2025 |
Proximity Interactome analyses unveil novel regulators of IRE1α canonical signaling S Le Goupil, C Philippe, H Laprade, M Lode, R Boniface, ... bioRxiv, 2024.10. 27.620453, 2024 | | 2024 |
The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts W Dalton, I Choi, J Ling, J Zhang, E Helmenstine, W Walter, R Bergman, ... | | 2023 |