Mycobacterium tuberculosis WhiB3 Maintains Redox Homeostasis by Regulating Virulence Lipid Anabolism to Modulate Macrophage Response A Singh, DK Crossman, D Mai, L Guidry, MI Voskuil, MB Renfrow, ... PLoS pathogens 5 (8), e1000545, 2009 | 344 | 2009 |
Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 M Naghavi, SE Vollset, KS Ikuta, LR Swetschinski, AP Gray, EE Wool, ... The Lancet 404 (10459), 1199-1226, 2024 | 259 | 2024 |
Mycobacterium tuberculosis WhiB3 responds to O2 and nitric oxide via its [4Fe-4S] cluster and is essential for nutrient starvation survival A Singh, L Guidry, KV Narasimhulu, D Mai, J Trombley, KE Redding, ... Proceedings of the National Academy of Sciences 104 (28), 11562-11567, 2007 | 232 | 2007 |
Reengineering Redox Sensitive GFP to Measure Mycothiol Redox Potential of Mycobacterium tuberculosis during Infection A Bhaskar, M Chawla, M Mehta, P Parikh, P Chandra, D Bhave, D Kumar, ... PLoS pathogens 10 (1), e1003902, 2014 | 219 | 2014 |
Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs R Singh, V Rao, H Shakila, R Gupta, A Khera, N Dhar, A Singh, A Koul, ... Molecular microbiology 50 (3), 751-762, 2003 | 199 | 2003 |
Dissecting virulence pathways of Mycobacterium tuberculosis through protein–protein association A Singh, D Mai, A Kumar, AJC Steyn Proceedings of the National Academy of Sciences 103 (30), 11346-11351, 2006 | 195 | 2006 |
Mycobacterium tuberculosis inhibits RAB7 recruitment to selectively modulate autophagy flux in macrophages P Chandra, S Ghanwat, SK Matta, SS Yadav, M Mehta, Z Siddiqui, ... Scientific reports 5 (1), 1-10, 2015 | 137 | 2015 |
Requirement of the mymA Operon for Appropriate Cell Wall Ultrastructure and Persistence of Mycobacterium tuberculosis in the Spleens of Guinea Pigs A Singh, R Gupta, RA Vishwakarma, PR Narayanan, CN Paramasivan, ... Journal of bacteriology 187 (12), 4173-4186, 2005 | 127 | 2005 |
Role of Mycobacterium tuberculosis Ser/Thr Kinase PknF: Implications in Glucose Transport and Cell Division P Deol, R Vohra, AK Saini, A Singh, H Chandra, P Chopra, TK Das, ... Journal of bacteriology 187 (10), 3415-3420, 2005 | 119 | 2005 |
Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo M Chawla, P Parikh, A Saxena, MH Munshi, M Mehta, D Mai, ... Molecular microbiology 85 (6), 1148-1165, 2012 | 116 | 2012 |
Hydrogen sulfide in physiology and pathogenesis of bacteria and viruses VK Pal, P Bandyopadhyay, A Singh IUBMB life 70 (5), 393-410, 2018 | 114 | 2018 |
“On demand” redox buffering by H 2 S contributes to antibiotic resistance revealed by a bacteria-specific H 2 S donor P Shukla, VS Khodade, M SharathChandra, P Chauhan, S Mishra, ... Chemical science 8 (7), 4967-4972, 2017 | 114 | 2017 |
mymA operon of Mycobacterium tuberculosis: its regulation and importance in the cell envelope A Singh, S Jain, S Gupta, T Das, AK Tyagi FEMS Microbiology Letters 227 (1), 53-63, 2003 | 112 | 2003 |
Mycobacterium tuberculosis WhiB3 responds to vacuolar pH-induced changes in mycothiol redox potential to modulate phagosomal maturation and virulence M Mehta, RS Rajmani, A Singh Journal of Biological Chemistry 291 (6), 2888-2903, 2016 | 107 | 2016 |
Protein kinase G confers survival advantage to Mycobacterium tuberculosis during latency-like conditions MZ Khan, A Bhaskar, S Upadhyay, P Kumari, RS Rajmani, P Jain, ... Journal of Biological Chemistry 292 (39), 16093-16108, 2017 | 102 | 2017 |
Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis R Mishra, S Kohli, N Malhotra, P Bandyopadhyay, M Mehta, MH Munshi, ... Science translational medicine 11 (518), eaaw6635, 2019 | 98 | 2019 |
Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh Free Radical Biology and Medicine 84, 344-354, 2015 | 91 | 2015 |
Reductive stress in microbes: implications for understanding Mycobacterium tuberculosis disease and persistence A Farhana, L Guidry, A Srivastava, A Singh, MK Hondalus, AJC Steyn Advances in microbial physiology 57, 43-117, 2010 | 67 | 2010 |
Measuring glutathione redox potential of HIV-1-infected macrophages A Bhaskar, MH Munshi, SZ Khan, S Fatima, R Arya, S Jameel, A Singh Journal of Biological Chemistry 290 (2), 1020-1038, 2015 | 64 | 2015 |
Efficacy of β-lactam/β-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis S Mishra, P Shukla, A Bhaskar, K Anand, P Baloni, RK Jha, A Mohan, ... Elife 6, e25624, 2017 | 62 | 2017 |