Defining the roles of TcdA and TcdB in localized gastrointestinal disease, systemic organ damage, and the host response during Clostridium difficile infections GP Carter, A Chakravorty, TA Pham Nguyen, S Mileto, F Schreiber, L Li, ... MBio 6 (3), 10.1128/mbio. 00551-15, 2015 | 292 | 2015 |
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease SJ Mileto, T Jardé, KO Childress, JL Jensen, AP Rogers, G Kerr, ... Proceedings of the National Academy of Sciences 117 (14), 8064-8073, 2020 | 94 | 2020 |
Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis J Huang, CP Kelly, K Bakirtzi, JA Villafuerte Gálvez, D Lyras, SJ Mileto, ... Nature microbiology 4 (2), 269-279, 2019 | 73 | 2019 |
Impact of enteric bacterial infections at and beyond the epithelial barrier AP Rogers, SJ Mileto, D Lyras Nature Reviews Microbiology 21 (4), 260-274, 2023 | 68 | 2023 |
Cryptosporidiosis modulates the gut microbiome and metabolism in a murine infection model AV Karpe, ML Hutton, SJ Mileto, ML James, C Evans, RM Shah, ... Metabolites 11 (6), 380, 2021 | 28 | 2021 |
Enterotoxic Clostridia: Clostridioides difficile Infections S Mileto, A Das, D Lyras Microbiology spectrum 7 (3), 10.1128/microbiolspec. gpp3-0015-2018, 2019 | 20 | 2019 |
Human plasminogen exacerbates Clostridioides difficile enteric disease and alters the spore surface MM Awad, ML Hutton, AJ Quek, WP Klare, SJ Mileto, K Mackin, D Ly, ... Gastroenterology 159 (4), 1431-1443. e6, 2020 | 13 | 2020 |
Bezlotoxumab prevents extraintestinal organ damage induced by Clostridioides difficile infection SJ Mileto, ML Hutton, SL Walton, A Das, LJ Ioannidis, D Ketagoda, ... Gut Microbes 14 (1), 2117504, 2022 | 11 | 2022 |
In silico, in vitro and in vivo analysis of putative virulence factors identified in large clostridial toxin-negative, binary toxin-producing C. difficile strains GO Androga, DR Knight, ML Hutton, SJ Mileto, ML James, C Evans, ... Anaerobe 60, 102083, 2019 | 9 | 2019 |
Antihypertensives and antibiotics: impact on intestinal dysfunction and hypertension SE Lucas, SL Walton, KM Mirabito Colafella, SJ Mileto, D Lyras, ... Hypertension 80 (7), 1393-1402, 2023 | 5 | 2023 |
Gut Microbial Perturbation and Host Response Induce Redox Pathway Upregulation along the Gut–Liver Axis during Giardiasis in C57BL/6J Mouse Model AV Karpe, ML Hutton, SJ Mileto, ML James, C Evans, AB Ghodke, ... International Journal of Molecular Sciences 24 (2), 1636, 2023 | 5 | 2023 |
Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis. Nat Microbiol 4: 269–279 J Huang, CP Kelly, K Bakirtzi, J Villafuerte, D Lyras, S Mileto, S Larcombe, ... | 5 | 2019 |
Using synthetic activity to design ultra-potent antibody cocktails H Zhao, M Dodds, M Tasch, M Gewe, A Martinez, M Hutton, K Keeney, ... | 4 | 2021 |
Using antibody synergy to engineer a high potency biologic cocktail against C. difficile H Zhao, M Tasch, M Dodds, M Gewe, A Martinez, M Hutton, K Keeney, ... bioRxiv, 2021.12. 21.473715, 2021 | 3 | 2021 |
A Clostridioides difficile endolysin modulates toxin secretion without cell lysis MM Awad, CD Suraweera, CJ Vidor, AY Ye-Lin, GC Williams, SJ Mileto, ... Communications Biology 7 (1), 1044, 2024 | | 2024 |
MLL1 directs gut-associated antibody responses to helminth and bacterial infections Y Zhang, C Chakma, A Kirn, A Zaini, R Farighi, L Xie, D Lopez-Urena, ... bioRxiv, 2024.08. 21.609083, 2024 | | 2024 |
Cryptosporidiosis modulates the gut microbiome metabolism and immune response in an infected host AV Karpe, ML Hutton, SJ Mileto, ML James, C Evans, RM Shah, ... | | 2021 |
Effect of plasmin (ogen) on: i) host ii) C difficile MM Awad, ML Hutton, AJ Quek, WP Klare, SJ Mileto, K Mackin, D Ly, ... Gastroenterology 1, 13, 2020 | | 2020 |
modulates toxin secretion without cell lysis MM Awad, CD Suraweera, CJ Vidor, AY Ye-Lin, GC Williams, SJ Mileto, ... | | |
Host responses to Clostridium difficile infection SJ MILETO Monash University, 0 | | |